Main Conference: May 28-31, 2007, Shanghai, China
Venue: Everbright Convention & Exhibition International Hotel (ECEIH), Shanghai, China
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| May 28, 2007, Monday |
Part One: Frontier Technology and Plenary Keynote Lectures
Session 1: Opening Ceremony and Plenary Keynote Lectures
(Place: Grand Ballroom, Floor 2, ECEIH)
| 08:20-08:40 |
Group Photos (Place: The Gate of ECEIH) |
| 09:00-09:05 |
Opening Remark |
| Host: Dr. Jianren Gu, Academician of CAE, Director of Shanghai Cancer Institute, China |
| 09:05-09:45 |
VIP Addresses |
| |
Dr. Bharat M. Chowrira, Vice President, Sirna Therapeutics Executive Director, Worldwide Licensing & External Research, Merck & Co, Inc , USA |
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Dr. Vaibhav Narayan, Manager of Discovery Informatics at Headquarters in Indianapolis, Lilly Systems Biology, Pte Ltd, USA |
| Keynote Forum: Frontier Technologies in Drug Discovery |
Chair: Dr. Guofan Hong, Professor of Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), China
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| 09:50-10:15 |
Title: Two Important Discoveries
Dr. Xinyuan Liu, Professor, member of CAS, China
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| 10:15-10:40 |
Title: A Chemists View of Innovation from Silicon Valley
Dr. Hans-Joachim Boehm, President and Head of Reseach Site, Roche Palo Alto, USA
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| 10:40-11:05 |
Title: The Challenges and Opportunities of the Current Global Health Care and Pharma Market
Dr. Bharat M.Chowrira, Vice President, Sirna Therapeutics Executive Director, Worldwide Licensing & External Research, Merck & Co, Inc , USA
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| 11:05-11:30 |
Title: Conceptual Concerns on Cancer Biology
Dr. Jianren Gu, Academician of CAE, Director of Shanghai Cancer Institute, Shanghai, China
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Part Two: Cutting-Edge and Enable Technologies for
Novel Drug of Discovery
Session 2: System Biology in Advanced Drug Discovery
(Place: Guang Da No. 8, Floor 2, ECEIH)
Session Chair: Dr. May Dongmei Wang, Georgia Cancer Coalition Distinguished Cancer Scholar, Director of Bioinformatics and Biocomputing Core in Emory-Georgia Tech Center of Cancer Nanotechnology Excellence (CCNE); Assistant Professor, Winship Cancer Institute, Georgia Institute of Technology and Emory University, USA
Co-Chair: Dr. Mark A. Tanouye, Professor, Department of Molecular and Cell Biology, University of California, Berkeley, USA
13:30-13:50 Title: Anti-epileptic Effects of Topoisomerase I inhibitors in a Drosophila Model of Epilepsy
Dr. Mark A. Tanouye, Professor, Department of Molecular and Cell Biology, University of California, Berkeley, USA
13:50-14:10 Title: Targeting Hedgehog Signaling Using Novel Small Molecule Inhibitors in Pancreatic Cancer and Brain Tumors
Dr. Wei Chen, Assistant Professor, Department of Medicine, Duke University Medical Center, USA
14:10-14:30 Title: Membrane Transporters 每 Roles In Drug Discovery
Dr. Guofeng You, Associate Professor, Department of Pharmaceutics, Rutgers University, NJ, USA
14:30-14:50 Title: Understanding Molecular Networks Underlying Effective Therapies in Human Malignancies from a Systems Point of View
Dr. Ji Zhang, Principal Investigator of Applied Genomics Lab, Institute of Health Sciences,
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University of medicine, China
14:50-15:10 Title: Drug-Target Identifications: (1) Affinity Purification of Proteins by Specific Ligand Immobilized on Resins, (2) T7 Phage Display Cloning of Drug-targeting Molecules
Dr. Fumio Sugawara, Professor of Chemical Biology, Genome and Drug Research Center, Department of Applied Biological Science, Tokyo University of Science, Japan
15:10-15:25 Coffee Break
15:25-15:45 Title: Novel Technology For Comprehensive Analyses of Oxidative Stress Biomarkers
Dr. Bo Zhang, Dept. of Cardiology, Fukuoka University, Japan
15:45-16:05 Title: Targeting Angiogenesis for Drug Discovery
Dr. Zhican Qu, Senior Scientist, Southern Research Institute, USA
16:05-16:25 Title: Natural Plant Products as Telomerase Inhibitors: Implications for Cancer Therapy
Dr. M. Prakash Hande, Associate Professor, Department of Physiology, Yong Loo Lin School of Medicine National University of Singapore, Singapore
16:25-16:45 Title: Systems Biology Approach to Construct a Dynamic Model of the Androgen Regulated Network During Prostate Cancer Progression
Dr. Biaoyang Lin, Professor, Zhejiang-California Nanoscience Institute, China
16:45-17:05 Title: NanoDrive: A Systems Biology Modeling and Visualization Tool for Nano-Particle Drug Study
Dr. May Dongmei Wang, Georgia Cancer Coalition Distinguished Cancer Scholar, Director of Bioinformatics and Biocomputing Core in Emory-Georgia Tech Center of Cancer Nanotechnology Excellence (CCNE); Assistant Professor, Winship Cancer Institute, Georgia Institute of Technology and Emory University, USA
17:05-17:25 Panel Discussion
Session 3: Roles of Functional Genomics and Proteomics in Drug Discovery
(Place: Guang Da No. 11, Floor 2, ECEIH)
Session Chair: Dr. Ling Yuan, Department of Plant and Soil Sciences. University of Kentucky, Lexington, U.S.A
Co-Chair:
Prof. Rohana Yusof, University Malaya, Malaysia
13:30-13:50 Title: Advanced Post Genomics Approaches for Discovery of Novel Therapies: Lessons from Tuberculosis to Influenza infections
Dr. Yossef Av-Gay, Associate Professor, University of British Columbia, Division of Infectious Diseases, Canada
13:50-14:10 Title: Roles of Highly Specific States of Genetic Expression in Functional and Drug Discovery
Dr. Hassan Fathallah-Shaykh, Associate Professor, Rush University Medical Center, Department of Neurological Sciences, USA
14:10-14:30 Title: Engineering Transcription Factors for Regulation of Secondary Metabolite Biosynthesis.
Dr. Ling Yuan, Department of Plant and Soil Sciences, University of Kentucky, Lexington, U.S.A
14:30-14:50 Title: The Possibility of Personalized Oncology Using ESP Combined With Next Generation Sequencing Technology
Dr. Colin Collins, Professor, UCSF Cancer Center, USA
14:50-15:05 Coffee Break
15:05-15:25 Title: SNP/Multi-Gene Express tech. and pharmacogenomics
Dr. Liang Xu, Beckman Coulter Inc, China
15:25-15:45 Title: Using Next Generation Technology for Genome Sequencing
Dr. Daixing Zhou, Illumina, Inc. Hayward, USA
15:45-16:05 Title: Genomics, Proteomics, Metabolomics to System Biology in Drug Discovery
Prof. Rohana Yusof, University Malaya, Malaysia
16:05-16:25 Title: Using Proteomics and Plumbagin to Explore New Targets for Anti-bacteria
Dr. Wan-Jr Syu, Dean, School of Life Sciences & Professor of Microbiology and Immunology, National Yang-Ming University,Taipei, Taiwan, China
16:25-16:45 Title: Towards Evolutionary Chronology of Natural Protein Ligands
Dr. Edward N. Trifonov, Head, Genome Diversity Center, Institute of Evolution, University of Haifa, Israel
16:45-17:05 Panel Discussion
Session 4: Small Interfering RNA (siRNA) / RNAi / miRNA
(Place: Guang Da No. 9, Floor 2, ECEIH)
Session Chair: Dr. Wei-Ping Min, Associate Professor, University of Western Ontario; President and CTO, ToleroTech Inc, Canada
Co-Chair: Dr. Levon M. Khachigian, Professor, President, Centre for Vascular Research, University of New South Wales, Sydney, Australia
13:30-14:00 Title: Anti-viral Myocarditis siRNAs Delivered Specifically to Target Cells by Packaging RNA Nanofibres
Dr. Decheng Yang, Professor, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
14:00-14:30 Title: Therapeutic Possibilities of Catalytic DNA
Dr. Levon M. Khachigian, Centre for Vascular Research, The University of New South Wales, Australia
14:30-15:00 Title: Genes Identification and Targets for Drug Discovery Using Bioinformatics
Professor Yi-Ping Phoebe Chen, Director of Bioinformatics Group, School of Engineering and Information Technology, Faculty of Science and Technology, Deakin University, Australia
15:00-15:15 Coffee Break
15:15-15:45 Title: RNAi-based Immune Therapy and Vaccine Development
Dr. Wei-Ping Min, Associate Professor, University of Western Ontario; President and CTO, ToleroTech Inc, Canada
15:45-16:15 Title: A New Method for Knockdown in Targeting Brain Region: RNAi with Local Electroporation
Dr. Yukio Akaneya, Division of Neurophysiology, Department of Neuroscience, Osaka University Graduate School of Medicine, Japan
16:15-16:45 Title: Using siRNA to Uncover Novel Ocogenic Signaling Pathway
Dr. Chi-Ying F. Huang, Associate Investigator in Institute of Cancer Research (National Health Research Institutes), Taiwan, China
16:45-17:30 Panel Discussion
Session 5: Stem Cell Therapy and Regenerative Medicine
(Place: Guang Da No. 7, Floor 2, ECEIH)
Session Chair: Mr. Bruce Cohen, CEO of Cellerant Therapeutics, USA
Co-Chair: Dr. Xiaoyan Jiang, Research Scientist, Terry Fox Laboratory, The BC Cancer Research Centre, Canada; Assistant Professor, University of British Columbia; Adjunct Professor, Shanghai Jiaotong University, China
13:30-13:55 Title: Challenges in Targeting Cancer Stem Cells: Lessons from Leukemia
Dr. Xiaoyan Jiang, Research Scientist, Terry Fox Laboratory, The BC Cancer Research Centre, Canada; Assistant Professor, University of British Columbia; Adjunct Professor, Shanghai Jiaotong University, China
13:55-14:20 Title: Anti-inflammatory effect of Mesenchymal Stem Cells: Novel Concept for Future Therapies
Dr. Mauricio Rojas, Assistant Professor of Department of Medicine; Associate Director CTRLung, Scholar McKelvey Lung Transplant Center, Emory University, Atlanta, USA
14:20-14:45 Title: Stem Cell Therapy: Developing a Successful Business Model
Mr. Bruce Cohen, CEO of Cellerant Therapeutics, USA
14:45-15:10 Title: Histone Deacetylases: Key Regulators to Determine the Efficiency of Reprogramming after Somatic-cell Nuclear Transfer
Dr. Satoshi Kishigami, Research Scientist of Center for Developmental Biology, Riken, Assistant Professor of Kinki University, Japan
15:10-15:25
Coffee Break
15:25-15:50 Title: Rescue of Human Dystrophin after Transplantation of Exon Skipping每Engineered Dmd Stem Cells in a Dystrophic Animal Model
Dr. Yvan Torrente, Assistant Professor of Neurology, University of Milan, Italy
15:50-16:15 Title: Stem Cell Regulation By Rho Gtpases
Dr. Yi Gu, Principal Scientist, Innovation Center, China, AstraZeneca Global R&D
16:15-16:40 Title: Insights Into Autotransplantation: The Unexpected Discovery Of Specific Induction Systems In Bone Marrow Stromal Cells
Dr. Mari Dezawa, Associate Professor, Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Japan
16:40-17:05 Title: Stem Cell Therapy for Cardiac Regeneration: Framework for the Future Optimization
Dr. Jozef Bartunek, Cardiovcascular Center, OLV Aalst, Belgium
17:05-17:30 Panel Discussion
18:00-20:00 Welcome Banquet
(Place: Grand Ballroom Front Hall, Floor 2, ECEIH)
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|
| May 29, 2007, Tuesday |
Part Three: Current Progress in Searching Anti-Major
Disease New Drugs
Session 6: Drug Discovery Case Studies of Major Diseases (Cardiovascular, Diabetes, Alzheimer Disease, AIDS)
(Place: Guang Da No. 7, Floor 2, ECEIH)
Session Chair: Dr. Gary Grover, Director, Product Safety Laboratories, Eurofins Scientific, USA
Co-Chair: Dr. Jingwen Liu, senior scientist Palo Alto VA Health Care Systems
08:30-08:50 Title: Human Monoclonal Antibodies against Viruses and Cancer
Dr. Xiaodong Xiao, Staff Scientist, Nanobiology Program, NCI, NIH, USA
08:50-09:10 Title: An Advance on the Obesity and Diabetes
Dr. Gary Grover, Director, Product Safety Laboratories, Eurofins Scientific, USA
09:10-09:30 Title: Upregulation of Long-chain Acyl-CoA Synthetases: A Novel Cellular Mechanism for Triglyceride Reduction
Dr. Jingwen Liu, Senior Scientist Palo Alto VA Health Care Systems, USA
09:30-09:50 Title: Boosting Antituberculosis Activity of Ethionamide
Dr. Vincent Villeret, Research Director, University de Lille 2-Institut de Biologie et Institut Pasteur de Lille, France
09:50-10:10 Title: Discovery and Function of a Super Interferon
Dr. Xinyuan Liu, Professor, member of CAS, China
10:10-10:25 Coffee Break
10:25-10:45 Title: Investigating Neurodegenerative Diseases with Molecular Simulation
Dr. Paolo Carloni, International School for Advanced Studies, Italy
10:45-11:05 Title: Discovery of Small Cell-permeable Molecules that Inhibit Histone Acetyl Transferase (HAT) Enzyme
Dr. Roberto Di Santo, Associated Professor in Medicinal Chemistry, University of Rome, Italy
11:05-11:25 Title: A Sensitive and Practical HPLC Method for Simultaneous D- and L-Serine Analysis in Cerebrospinal Fluid and Its Application to Pain and CNS Diseases
Dr. Shinro Tachibana, Senior Research Fellow, Department of Anaesthesia, National University Hospital Of Singapore, Singapore
11:25-11:45 Title: Discovery of Minozac: a Disease-Modifying drug candidate for Alzheimer's disease
Dr. Wenhui Hu, Currently Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, China
11:45-12:05 Title: Metallothioneins (MTs), Anti-aging and Alzheimers Disease (AD)
Dr. Binggen Ru, Professor, Group of Protein Structure and Function, College of Life Science, Peking University, Beijing, China
Session 7: Advances in the Pathology and Pharmacology of Major Diseases Drug Discovery
(Place: Guang Da No. 9, Floor 2, ECEIH)
Session Chair: Dr. Manuela Rodriquez, Visiting Scientist, Broad Institute of Harvard and MIT, USA
Co-Chair: Dr. Moshe Szyf, Professor Department of Pharmacology and Therapeutics McGill University Canada
08:30-08:50 Title: New Findings of Neuro-Oncological Drug Discovery
Dr. Francis Ali-Osman, Margaret Harris and David Silverman Distinguished Professor of Neuro-Oncology Research, Department of Surgery, Duke University School of Medicine, USA
08:50-09:10 Title: Identification of a Pathway Selective Lxr Modulator through Structure-Guided Ligand Design
Dr. Mohamed Boudjelal, Investigator, BRAD, GlaxoSmithKline, UK
09:10-09:30 Title: DNA Demethylation and Cancer Metastasis: Therapeutic Implications
Dr. Moshe Szyf, Professor Department of Pharmacology and Therapeutics McGill University Canada
09:30-09:50 Title: Non-invasive Fluorescent Imaging for Profiling Developmental Neurotoxicity in Transgenic Mice
Dr. Zhuo Lang, Principal Scientist, Institute of Bioengineering and Nanotechnology, Singapore
09:50-10:10 Title: Chemistry and Biology of Chromatin Remodeling Agents
Dr. Manuela Rodriquez, Visiting Scientist, Broad Institute of Harvard and MIT, USA
10:10-10:25 Coffee Break
10:25-10:45 Title: Pandemic Preparedness, Influenza Transmission And Prevention: Gaseous Nitric Oxide As A First Line Antimicrobial Treatment Against Highly Pathogenic Influenza Infection
Dr. Chris Miller, Pulmonox Medical Inc., Canada
10:45-11:05 Title: Known Targets and Chemotypes with New and Unexpected Therapeutic Potential
Dr. Jochen Antel, Solvay Pharmaceuticals Research Laboratories, Germany
11:05-11:25 Title: Therapeutic Promise Of C-Jun N-Terminal Kinase (Jnk) Inhibitors
Dr. Marie A. Bogoyevitch, Biochemistry and Molecular Biology, University of Western Australia, Australia
11:25-11:45 Title: Ligand-directed Targeting and Molecular Genetic Imaging in Diseases with an Angiogenesis Component
Dr. Wadih Arap, Stringer Professor of Medicine and Cancer Biology, USA
Dr. Renata Pasqualini, Professor of Medicine and Cancer Biology, University of Texas M.D. Anderson Cancer Center, USA
11:45-12:05 Title: Combinatorial Effects of Doxorubicin and STI571 on Growth, Differentiation and Apoptosis of CML Cell Line K562
Dr. Malgorzata Czyz, Head of Department of Molecular Biology of Cancer, Medical University of Lodz, Poland
Session 8: Optimize the Development and Review Processes for New Cancer Drugs (Part I)
(Place: Guang Da No. 8, Floor 2, ECEIH)
Session Chair: Dr. Gary T Wang, Associate Research Fellow, Cancer Research, Abbott Laboratories, USA
Co-Chair: Dr. Blanka Rihova, Director, The Institute of Microbiology, Academy of Sciences, The Czech Republic
08:30-08:50 Title: Anti-cancer Drug Discovery
Dr. Gary T Wang, Associate Research Fellow, Cancer Research, Abbott Laboratories, USA
08:50-09:10 Title: Immunomodulating Polymer-based Nanotherapeutics with Cytostatic Activity
Dr. Blanka Rihova, Director, the Institute of Microbiology, Academy of Sciences, The Czech Republic
09:10-09:30 Title: Antagonists of IAPs for Anticancer Therapy: A Structure-based Drug Discovery Approach to a Protein-protein Interaction Target
Dr. Zhuoliang (Julian) Chen, Senior Research Investigator, Novartis Institutes for BioMedical Research, Inc., Global Discovery Chemistry, USA
09:30-09:50 Title: Efficient Anticancer Drugs Have Promiscous Mechanisms of Action
Dr. Stig Linder, Professor of Experimental Oncology, Cancer center Karolinska, Department of Oncology-Pathology, Karolinska Institute, Sweden
09:50-10:05 Coffee Break
10:05-10:25 Title: Developing Novel Drug Molecules That Target Epigenetic Enzymes
Dr. Yujun George Zheng, Department of Chemistry, Georgia State University, USA
10:25-10:45 Title: New Drug Target I. T-type Ca2+ Channels
Dr. Ming Li, Associate Professor of Pharmacology & Physiology, Physiology, Tulane University Health Sciences Center, USA
10:45-11:05 Title: Tumor Cell-Specific Nuclear Targeting
Dr. David A. Jans, Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Australia
11:05-11:25 Title: Aurora Kinases and Their Inhibitors: More than One Target and One Drug
Dr. J邦rgen Moll, Director Cell Biology Department of Nerviano Medical Sciences Srl., Italy
11:25-11:45 Title: Inhibition of the Extracelluar Matrix of the Tumor Microenvironment as a Novel Strategy for Cancer Treatment, Effect of Halofuginone
Dr. Mark Pines, Senior Scientist, Institute of Animal Sciences, Agricultural Research Organization, Israel
Session 9: Vaccines and Inflammatory Disease Drug Discovery and Development
(Place: Guang Da No. 11, Floor 2, ECEIH)
Session Chair: Dr. Jonathan P. Wong, Molecular Biology Group, Defence R&D Canada 每 Suffield, Alberta, Canada
Co-Chair: Dr. Andy Teng, Associate Profesor, Director, Lab of Molecular Microbial Immunity
Eastman Dental Center, and Deptartment of Microbiology and Immunology School of Medicine and Dentsitry, University of Rochester Medical Center Rochester, New York, USA
08:30-08:55 Title: Vaccine Immunity 每 a Global Interest
Dr. Kent Van Kampen, Vaxin lnc, Birmingham, USA
08:55-09:20 Title: Therapeutic Human ScFv-antibody for Treating Aggregatibacter Actinomycetemcomitans-mediated Mucosal Infection
Dr. Andy Teng, Associate Profesor, Director, Lab of Molecular Microbial Immunity
Eastman Dental Center, and Deptartment of Microbiology and Immunology School of Medicine and Dentsitry, University of Rochester Medical Center Rochester, New York, USA
09:20-09:45 Title: Development of Novel Influenza Virosome Based Synthetic Malaria Vaccines
Dr. Claudia Daubenberger, Deptartment of Medical Parasitology and Infection Biology, Swiss Tropical Institute (STI)
09:45-10:05 Title: Non-replicating Adenovirus-vectored Bird flu Vaccine
Dr. De-chu c. Tang, Vaxin lnc, Birmingham, USA
10:05-10:20 Coffee Break
10:20-10:45 Title: Development of Novel Nucleic Acid-based Antiviral Agents against Seasonal and Avian Influenza Viruses
Dr. Jonathan P. Wong, Molecular Biology Group, Defence R&D Canada 每 Suffield, Alberta, Canada
10:45-11:10 Title: Fibrinogen As a Signaling Molecule and a Therapeutic Target in Multiple Sclerosis
Dr. Katerina Akassoglou, Assistant Professor, Department of Pharmacology, School of Medicine, University of California, San Diego, USA
11:10-11:35 Title: Targeting Innate Immune Response Receptors and Ligands to Fight Sepsis
Dr. Roman Jerala, Professor, Laboratory for Molecular Modeling and NMR Spectroscopy, National Institute of Chemistry, Ljubljana, Slovenia
12:00-13:00 Luncheon
Part Four: Novel Tools and IT Platform for Drug Discovery
Session 10: New Biomarkers and High Throughput Screening Technology for Finding Hits, Leads and Preclinical Drug Candidates
(Place: Guang Da No. 11, Floor 2, ECEIH)
Session Chair: Dr. Xueheng Cheng, Sr. Group Leader, Biological Screening, Abbott Laboratories, USA
Co-Chair: Dr. Darius M. Dziuda, Assistant Professor, Data Mining and Statistics, Department of Mathematical Sciences, Central Connecticut State University, USA
13:30-13:55 Title: An Efficient BAF/3-based Compound Profiling System for Kinase Inhibitor Identification and Development
Dr. Xiang-ju Gu, Group leader, Kinase Screening, Genomics Institute of the Novartis Research Foundation, USA
13:55-14:20 Title: Evaluation of Approved Pharmaceutical Substances with a 汕-Lactamase-Expressing Amastigote-Based Throughput Assay for Novel Therapies of Leishmaniasis
Dr. Suping Jiang, Chief, Department of Biology, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, USA
14:20-14:45 Title: Drugs Effects and Drug Targets: Inhibition of Disulfide Reducing Enzymes and Antiproliferative Effects by Neuroleptics, Antimycotics, Antibiotics and other Drugs on Human Pathogenic Amoebas
Dr. R. N. Ondarza, Professor of Biochemistry, Faculty of Medicine, UNAM, Mexico, D.F. and Researcher on Medical Sciences, Center of Research on Infectious Diseases, INSP, Cuernavaca, Morelos, Mexico
14:45-15:10 Title: Development of High Throughput And High Content Tools To Identify Novel Biomarkers And Drug Targets Related To The Assembly, Fusion And Elimination Of Lipid Droplets
Dr. Gerd Schmitz, Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Germany
15:10-15:25 Coffee Break
15:25-15:50 Title: TRPV1 as a Target for Next Generation Analgesics
Dr. Louis S. Premkumar, Department of Pharmacology, Southern Illinois University School of Medicine Springfield, USA
15:50-16:15 Title: Drug Discovery and Development in Molecular Imaging
Dr. Yanming Wang, Departments of Chemistry and Radiology, Case Center for Imaging Research, Case Western Reserve University, USA
16:15-16:40 Title: Multivariate Biomarkers and The Informative Set of Genes
Dr. Darius M. Dziuda, Assistant Professor, Data Mining and Statistics, Department of Mathematical Sciences, Central Connecticut State University, USA
16:40-17:05 Title: Affinity Selection/mass Spectrometry, an Ultraefficient Affinity Screening Method and an Enabling Tool for Drug Discovery in the Post-genomics Era
Dr. Xueheng Cheng, Sr. Group Leader, Biological Screening, Abbott Laboratories, USA
17:05-17:30 Panel Discussion
Session 11: Enhancing Medicinal Chemistry Productivity and SAR Studies for Better Drugs
(Place: Guang Da No. 9, Floor 2, ECEIH)
Session Chair: Dr. Zhijian Lu, Department of Basic Chemistry, Merck Research Laboratories, Merck & Co., Inc., USA
Co-Chair: Dr. Ruo Xu, Principle scientist, Schering-Plough Corporation, USA
13:30-13:55 Title: Discovery of Potent and Selective 5-HT1F Receptor Agonists for the Treatment of Acute Migraine
Dr. Deyi Zhang, Principal Research Scientist, Eli Lilly and Company, Indianapolis, USA
13:55-14:20 Title: Second Generation Protease Inhibitors against Resistant HIV-1 Viral Variants
Dr. Zhijian Lu, Department of Basic Chemistry, Merck Research Laboratories, Merck & Co., Inc., USA
14:20-14:45 Title: Yeast Hormone Bioassays: The Only Way to Measure Specific Hormone Activity. A New Yeast Androgen Biosensor, Enabling To Check Findings of QSAR Model Approaches
Dr. Toine F.H. Bovee, Institute of Food Safety, Wageningen University and Research Center, Wageningen, the Netherlands
14:45-15:10 Title: Development of Plant Polyphenols as Potential Sensitizers for Cancer Chemotherapy
Dr. Kai Zhang, Dept of Experimental Surgery, Singapore General Hospital, Singapore
15:10-15:25 Coffee Break
15:25-15:50 Title: Structure-based Discovery of Novel Antibacterials
Dr. Tom Solmajer, Professor of Medicinal Chemistry National Institute of Chemistry and Lek Pharmaceuticals d.d, Slovenia
15:50-16:15 Title: Bicyclic [4.1.0] Heptanes as Phenyl Replacements for Melanin Concentrating Hormone (MCH) Receptor Antagonists
Dr. Ruo Xu, Principle scientist, Schering-Plough Corporation, USA
16:15-16:40 Title: White-biocatalysis for Drug Synthesis
Dr. Cristina Silva Pereira, Professor, IBET, Portugal
16:40-17:05 Panel Discussion
Session 12: IT/Informatics Solution for Integrated Drug Discovery
(Place: Guang Da No. 7, Floor 2, ECEIH)
Session Chair: Dr. Peter Meek, Department of Chemistry & Biochem, University of the Sciences Philadelphia, USA
Co-Chair: Dr. Yi-Ping Phoebe Chen, Associate Professor (Reader), Director of Bioinformatics Group, School of Engineering and Information Technology, Faculty of Science and Technology, Deakin University, Australia
13:30-13:55 Title: Molecular Design of a morphomatstatin-like using Molecular Dynamics Simulations : from the native sequence to a new bioactive mimetic peptidic drug
Dr. Alain JP Alix, Laboratory of Biomolecular Spectroscopy and Structure, Faculty of Natural and Exact Sciences, Federative Research Institute "Biomolecules", University of Reims Champagne-Ardenne, France
13:55-14:20 Title: To Bind, or not to Bind that is the Question: Strategies for Drug
Classification and Design
Dr. Ernst-Walter Knapp, Free University of Berlin, Department of Biology, Chemistry, Pharmacy, Institute of Chemistry, Macromolecular Modeling and Simulation of Biomolecular Systems, Germany
14:20-14:45 Title: Shape Signatures: Computer Aided Drug Design from a Non-specialist Viewpoint
Dr. Peter Meek, Department of Chemistry & Biochem, University of the Sciences Philadelphia,
USA
14:45-15:10 Title: Modeling Protein-Ligand Interactions
Prof. Noorsaadah Abd Rahman, Universiti Malaya, Malaysia
15:10-15:25 Coffee Break
15:25-15:50 Title: De Novo Molecular Design: A Powerful Strategy for the Discovery of New Potential Antimalarials
Dr. Colin W.G. Fishwick, Reader in Organic Chemistry, University of Leeds, School of Chemistry, UK
15:50-16:15 Title: Integrative Informatics at Eli Lilly and Company: Applications Aacross the Drug Discovery and Development Pipeline
Dr. Vaibhav Narayan, Manager of Discovery Informatics at Headquarters in
Indianapolis, Lilly Systems Biology, Pte Ltd, USA
16:15-16:40 Title: Statistical Prediction of Protein-chemical Interactions Based on Chemical Structure and Mass Spectrometry Data
Dr. Yasubumi Sakakibara, Professor, Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Japan
16:40-17:05 Title: Integrated Approach for Structure-based Virtual Screening
Dr. Sukjoon Yoon, Assistant Professor, Department of Biological Sciences, Research Center for Women's Diseases, Sookmyung Women's University, Korea
17:05-17:30 Panel Discussion
Session 13: Solutions to Novel Drug Delivery System
(Place: Guang Da No. 8, Floor 2, ECEIH)
Session Chair: Dr. Ram I. Mahato, Associate Professor, Protein/Nucleic Acid Delivery and Targeting Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, USA
Co-Chair: Dr. Z. Ryan Tian, Assistant Professor, University of Arkansas, USA
13:30-13:55 Title: Biomimetic Interfaces for Drug Discovery or Layer by Layer Techniques for Drug Delivery
Dr. Ilsoon Lee, Assistant Professor, Department of Chemical Engineering & Materials Science, Michigan State University, USA
13:55-14:20 Title: Site-specific Delivery and Targeting of Oligonucleotides and siRNA for Treating Hepatitis and Liver Fibrosis
Dr. Ram I. Mahato, Associate Professor, Protein/Nucleic Acid Delivery and Targeting, Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, USA
14:20-14:45 Title: Preparation and Application of Drug Delivery Using Hollow Fiber Technology
Dr. Limin Zhu, Institute of Biological Sciences & Biotechnology, Donghua University, Songjiang University City, China
14:45-15:00 Coffee Break
15:00-15:25 Title: Application of Recombinant Albumin to Drug Delivery System
Dr. Masaki Otagiri, Professor of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Japan
15:25-15:50 Title: Developing Nanobiomaterials and Nanorobots for Therapeutic and Regenerative Nanomedicines
Dr. Z. Ryan Tian, Assistant Professor, University of Arkansas, USA
15:50-16:15 Title: Nanomedicine in Drug Discovery and Drug Delivery
Dr. Chiming Wei, Professor, Johns Hopkins University School of Medicine, President, American Academy of Nanomedicine, USA
17:40-18:30 Recruitment Talk (Lilly Singapore Center for Drug Discovery)
(Place: Guang Da No. 8, Floor 2, ECEIH)
18:30-19:30 Reception Banquet ( Sponsored by Lilly Singapore Center for Drug Discovery )
(Place: Guang Da No. 1, Floor 2, ECEIH)
|
| May 30, 2007,
Wednesday |
Session 14: Exploring Chemistry Strength and Natural Products by High Population of Talents
(Place: Guang Da No. 11, Floor 2, ECEIH)
Session Chair: Dr. Vanderlan da Silva Bolzani, Professor of Institute of Chemistry, Sao Paulo State University, Vice-President of the Brazilian Chemical Society, Brazil
Co-Chair: Dr. K. K. Bhutani, Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), India
08:30-08:50 Title: Brief Introduction of World Traditional Medicine Patent Database
Dr. Yanhuai Liu, President, Beijing East Linden Science & Technology Co., Ltd., China
08:50-09:10 Title: Curcumin Inhibition of mTOR Signaling
Dr. Shile Huang, Assistant Professor, Louisiana State University Health Sciences Center, USA
09:10-09:30 Title: Development And Discovery Of Natural Products - Rationalising Indian Traditional Medicines
Dr. K. K. Bhutani, Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), India
09:30-09:50 Title: Effects of Extracts of Artemisia diffusa against Plasmodium berghei, as a New Antimalarial Agent
Dr. Abdolhossein Rustaiyan, Department of Chemistry, Science and Research Campus, I.A.University, Iran
09:50-10:05 Coffee Break
10:05-10:25 Title: Current Developments on Drug Discovery From Brazilian Biodiversity
Dr. Vanderlan da Silva Bolzani, Professor of Institute of Chemistry, Sao Paulo State University, Vice-President of the Brazilian Chemical Society, Brazil
10:25-10:45 Title: New Drug Discovery〞by TCM Database
Mr. Hua Su, Director of Informatics Department, Shanghai Innovative Research Center of Traditional Chinese Medicine, China
10:45-11:05 Title: New Opportunties for Drug Discovery for Tropical Diseases
Dr. Solomon Nwaka, Manager, Genomics and Discovery Research, TDR, World Health Organization (WHO), Switzerland
11:05-11:25 Title: Development of Antimalarials from Medicinal Brazilian Plants Extracts and Synthetic Molecules with Emphasis on Artemisinin Combinations
Dr. Antoniana Ursine Krettli, Professor, Centro de Pesquisas Ren谷 Rachou, Brazil
11:25-11:45 Title: Biologically and Physiologically Active Marine Natural Products
Dr. K. Nakamura & Dr. D. Uemura, Department of Chemistry, Graduate School of Science, Nagoya University, Japan
12:00-13:00 Luncheon
Session 15: Optimize the Development and Review Processes for New Cancer Drugs (Part II)
(Place: Guang Da No. 11, Floor 2, ECEIH)
Session Chair: Dr. Colin Collins, Professor, UCSF Cancer Center, USA
Co-Chair: Dr. Jun-Ping Liu, Professor of Monash University, Australia
13:30-13:50 Title: Targeting Gene-Virotherapy of Cancer
Dr. Xinyuan Liu, Professor, member of CAS, China
13:50-14:10 Title: A Novel Small Molecule Inhibits Tumor Growth by Targeting Telomerase Activity
Dr. Jun-Ping Liu, Professor of Monash University, Australia
14:10-14:30 Title: A New Paradigm in New Drug Development from CMC Preclinical Study to Clinic Evaluation: The Emerging Roles of China in Global Drug Development
Dr. Yu L. Huang, CTO, Bio-Cancer Treatment International Limited, China
14:30-14:50 Title: New Insights into Anticancer Therapeutic
Dr. Robert J. Hickey, Associate Professor, Indiana University, USA
14:50-15:05 Coffee Break
15:05-15:25 Title: RhoC and Metastasis in Liver Cancer
Dr. Mary Waye, Professor, Department of Biochemistry, The Chinese University of Hong Kong, China
15:25-15:45 Title: Targeting Acid Ceramidase: A New Strategy To Enhance Combination Therapy of Cancer
Dr. James S. Norris, Professor and Chairman, Department of Microbiology & Immunology at the Medical University of South Carolina, USA
15:45-16:05 Title: Targeting Delivery of Cytokines to Tumor Neovasculature
Dr. Angelo Corti, Professor of Biochemistry, Department of Oncology, San Raffaele Scientific Institute, Italy
16:05-16:25 Title: Molecular Mechanism of RecQ Helicases Function in Human Cancers and Premature Aging Syndromes
Dr. Jin-Shan Hu, associate professor, Department of Basic Medical Sciences, COMP, Western University of Health Sciences, USA
Part Five: Overseas Chinese Scholar Entrepreneurship Forum
Part I : Opportunities and Challenges of Seeking Venture Capitals in Biotechnological and Pharmaceutical Sectors in China
(Place: Guang Da No. 7, Floor 2, ECEIH)
Session Chair: Mr. Fan Zhang, Founding partner of Sequoia Capital China, China
Co-Chair: Dr. Dongxu Qiu, Managing Director of HUYA China, China
08:30-08:55
Mr. Kevin Xie, Partner, China Renaissance Partners, China
08:55-09:20 Dr. Greg B. Scott, President and Founder of ChinaBio Accelerator and
President and Co-founder of Life Science Angels, USA
09:20-09:45 Title: Patent Related Issues for Products Imported Into the United States
Dr. Susan Fentress, Butler, Snow, O'Mara Stevens & Cannada, PLLC, USA
09:45-10:10 Dr. Dongxu Qiu, Managing Director of HUYA China, China
10:10-10:25 Coffee Break
10:25-10:50 Mr. Tianpin Wu, President, HK Wonderful International Investment Group, China
10:50-11:15 Title: Evaluation of Invention: How to Assess the Quality of A Patent
Dr. Jacqueline Lui, Managing Director, Eagle IP Limited, Hongkong, China
11:15-11:40 Title: Qiming Venture Partners' opinion to the investment opportunity in the biomedical field of China
Mr. William Hu, Qiming Venture Partners, China
12:00-13:00 Luncheon
Part II : Case Studies of Overseas Chinese Scholar Entrepreneurship
(Place: Guang Da No. 7, Floor 2, ECEIH)
13:30-13:35 Opening Remark
13:35-14:00 Introduction to the innovation policies for the overseas Chinese of Shanghai
Mr. Weimao Huang, Director of International Exchange & Cooperation Department, Shanghai Municipal Bureau of Foreign Experts, China
14:00-15:00 Introduction to the Preferential Policies of Innovation Enacted by the Government
Speakers:
Delegate of Shanghai Zhangjiang Overseas Chinese Students Pioneer Park, China
Delegate of Shanghai XinMin New Hi-Tech & Returned Students Science Undertaking Zone, China
Delegate of Suzhou SciTech Pioneering Park, China
Delegate of
Wuxi Scientific and Technical Pioneering Park, China
15:00-15:20 Project Recommendation
Dr. Wei-Ping Min, Associate Professor, University of Western Ontario; President and CTO, ToleroTech Inc, Canada
15:20-16:00 Innovation Experience Exchange on Innovation
Speakers:
Dr. Peizuo Zhang, CEO of Shanghai GenePharma Co., Ltd, China
Dr. Guojin Zhao, President and CEO of Shanghai Jiemei Genomics, Inc., China
16:00-16:30 Overseas Chinese ask questions about how to start up business after returning and the discussion among each innovation park
16:30-17:30 Free Communication
18:00-19:00 Supper
Part Six: Business Forum
Training Workshop : Find Strategic Alliance to Meet Regulatory requirement through CRO (Part I )
Session Chair: Dr. Gunter H. Ruetter, the President of the Monitoring Force Group, Germany
18:30-19:10 Title: Build up a speciality CRO team in China
Dr. Peter Liu, Medical Director, Excel PharmaStudies Inc.
19:10-20:10 Title: The Management of Global Clinical Trials (Part I)
Dr. Gunter H. Ruetter, the President of the Monitoring Force Group, Germany
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| May 31, 2007, Thursday |
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Training Workshop : Find Strategic Alliance to Meet Regulatory requirement through CRO (Part II )
Session Chair: Dr. Gunter H. Ruetter, the President of the Monitoring Force Group, USA
09:00-10:30 Title: The Changing Role of Contract Research Organizations (CROs) in the Management of Global Clinical Trials
Christine Healy-Rendel,
Business Development Manager, Monitoring Force USA, Inc.
10:30-11:30 Title: The Management of Global Clinical Trials (Part Two)
Dr. Gunter H. Ruetter, the President of the Monitoring Force Group, USA
12:00-13:00 Luncheon
13:30-15:00 Title: Assessing CRO Role and Opportunities in a Growing Economy
Dr. Sergei Drapkin, Chief Executive Officer, the Monitoring Force Group, Russia
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