Session Chair:

Keynote Speech
Title: Artificial Cells Containing Stem Cells for Regenerative Medicine
Dr. Thomas Ming Swi Chang, Director, Artificial Cells & Organs Research Centre, McGill
University, Canada

Title: Transdifferentiation of Bone Marrow Stromal Cells into Neuronal Cells and Its Application for Regenerative Medicine
Dr. Masaaki Kitada, Associate Professor, Department of Stem Cell Biology and Histology, Tohoku Univeristy Graduate School of Medicine, Japan

Title: The Discovery and Development of Botanic Drug Ph-3 Based on Regenerative Medicine: From Discovery to Clinical Trial
Dr. Rong-Tsun Wu, Professor & Director, Research Center for Drug Discovery, Institute of
Biopharmaceutical Science, National Yang-Ming University, Taiwan

Session Chair:

Co-Chair:

Keynote Speech
Title: Finding Novel Cancer Drugs that Address Unmet Medical Needs
Dr. Michael R. Briggs,Senior Director and Head of Cell & Molecular Biology, Vertex Pharmaceuticals, Inc., USA

Title: P25/CDK5 Inhibitors for AD Therapeutics
Dr. Ilho Ha, Director, BioScience Center Hanwha Chemical R & D Institute Hanwha Chemical Co., Korea

Title:Arsenic Trioxide - Teaching an Old Drug New Tricks
Dr. Meir Wetzler, Chief, Division of Leukemia, Department of Medicine, University of New York at Buffalo, USA

Title: β Peptide, A Potential New Anti-metastasis Peptide: Expression and Anti-metastasis Ability
Dr. Yinkun Liu, Deputy Director, Liver Cancer Institute of Fudan University, China

Title: Wisdom: Grid Computing Enabled Identification of Active Molecules Against Targets Implicated in Malaria
Dr. Ana Lucia Da Costa, CNRS, Clermont-Ferrand, France

Title: The Mosquito Sodium Channel: Adaptive Changes of Amino Acid and Codon Biases in the Evolution of Pyrethroid Resistance
Dr. Nannan Liu, Associate Professor, Department of Entomology and Plant Pathology, Auburn University, Auburn, USA

Title: Novel Technologies for Expediting Drug Discovery Research
Dr. Keming Song, R&D Manager, Sigma-Aldrich Corporation, USA

Title: KH902, A Potentially Better Therapy for Neovascular Age-Related Macular Degeneration
Dr. Dechao Michael Yu, CEO, Kanghong Biotech Co. Ltd., China

Session Chair:

Keynote Speech
Title: Use of Cannabinoids as Novel Anti-inflammatory Drugs through Potential Targeting of CB2 Receptors
Dr. Prakash Nagarkatti,Associate Dean for Basic Sciences, University of South Carolina School of Medicine, USA

Title: Cytokine Profile of T Cells in Pregnancy
Dr. Marie-Pierre Piccinni, Professor, University of Florence, Italy

Title: Cholera Toxin B Subunit-based Fusion Proteins: An Approach to Design New Adjuvanted Vaccines
Dr. Ana Paula de Mattos Areas, Natural and Human Sciences Center, Federal University of ABC, Brazil

Session Chair:

Co-Chair:

Title: Efficient Selection of Monoclonal Antibodies to Rabies Virus Using Ribosome Display Technology
Dr. Xiao-Ling Zhao, Associate Professor, Institute of Health and Enviramental Medicine, China

Title: IIdentification of AK-1 for Protection against Radiation Damage and Ak-2 & Ak-8 for Protection against a Broad-spectrum Viral Infection
Dr. Grace Wong, Founder, President & CSO, ActoKine Therapeutics, USA

Title: Generic Vaccines against Threat Pathogens
Dr. Jian Song, Staff Scientist, Los Alamos National Laboratory, USA

Title: Designs and Efficacies of Broad-spectrum and Virus-specific Approaches Using Uucleic Acid-based Aagents against Influenza A Viruses
Dr. Jonathan P. Wong, Research Scientist, Chemical & Biological Defence Section, Defence R & D Canada - Suffield (DRDC Suffield), Canada

Session Chair:

Co-Chair:

Dr. M Asif Chaudry,University Department of Surgery Royal Free & University College London, UK

Keynote Speech
Title: Tumor-Selective Anticancer Drugs from Amphiphilic Organophosphazenes
Dr. Youn Soo Sohn, Distinguished Professor, Department of Chemistry, Division of Nano Science, Ewha Womans University, Korea

Title: Multiple Target Tyrosine Kinase Inhibitors
Dr. Tang Peng Cho, Chief Scientific Officer, Shanghai Hengrui Pharmaceuticals, China

Title: Targeting the Cannabinoid System as a Novel Therapeutic Modality to Treat Cancers of the Immune System
Dr. Mitzi Nagarkatti, Deputy Director of Cancer, University of South Carolina, USA

Title: Fragment Based Drug Discovery Using Rational Design
Dr. Harren Jhoti, Chief Executive Officer & Founder, Astex Therapeutics, Cambridge, UK

Title: A Human Tumor Genome Project: From Sequence to Structure, Function and Possibly Drug Targets
Dr. Laszlo Homolya, Senior Scientist, Research Group for Membrane Biology, Semmelweis
University, Hungarian Academy of Sciences, Hungary

Title: Targeting Multidrug Resistant Cancer
Dr. Gergely Szakacs, Professor, Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, Budapest, Hungary

Title: Target Therapy in Cancer
Dr. Valentina Tzekova, Professor, University Hospital "Queen Joanna", Bulgaria

Title: Identification of Cyano Indenopyrazine Derivatives as a Novel Series of Potent Ubiquitin-Specific Protease Inhibitors
Dr. Frédéric Colland, Director, Biological Research, Hybrigenics Pharma, France

Title: Phage Display: A Magic Tool for Cancer Biology
Dr. Zonghai Li, Associate Professor, State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai, China

Session Chair:

Co-Chair:

Title: Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases): What Can Be Learned by Studies on Cu(II)-peptide Complexes
Dr. Gianni Valensin, Professor, Director of the NMR Centre of the University of Siena, Italy

Title: Opioid Antagonist Treatment and Alcohol Consumption: Role of Dose, Gender and
Pharmacologic Strategy
Dr. Jorge Juárez, Professor, Universidad de Guadalajara, México

Title: TCA Cycle May Play an Important Role for Protection Against Epileptic Seizures
Dr. Hiro-aki Yamamoto, Associate Professor, University of Tsukuba, Japan

Title: Innovation in Neuroscience：The Useful Tools for Drug Discovery
Dr. Yi Wang, Training Manager and Field Application Scientist, Millipore Corp, China

Title: Neurovascular Dysfunction in Dementia: Cholinesterase Inhibitors
Dr. Sabina Janciauskiene, Associate Professor, Department of Clinical Sciences, Lund University, Sweden

Session Chair:

Co-Chair:

Title: 3D Cellular Models for Hepatotoxicity
Dr. Hanry Yu, Associate Professor, National University of Singapore, Singapore

Title: Cyclic Arg-Gly-Asp Peptide-Labeled Liposomes Fpr Targeting Drug Therapy of Hepatic Fibrosis in Rats
Dr. Jiyao Wang, Professor & Chair, GI & Hepatology, Shanghai Medical College, Fudan University, China

Title: Replicative HBV Transgenic Mice and Its Use in Drug Evaluation
Mr. Xue-Rui Yi, The Liver Center of PLA, The 458 Hospital in Guangzhou, Guangzhou, China

Session Chair:

Keynote Speech
Title: De-risk Adverse Drug Reaction Potential in Drug Discovery and Development
Dr. Tian J Yang, Research Leader, Roche Pharmaceuticals, USA

Title: Clays and Their Beneficial Effects upon Skin
Dr. Carmen del Hoyo Martínez, Professor, University of Salamanca, Spain

Title: Pharmacoepidemiology Studies about Drugs and Herbal Medicine during Breastfeeding, How to Protect Neonate and Infant from Harmful Compounds during Breastfeeding
Dr. Raphael Serreau, Physician Specialist, Necker Hospital in Paris, France

Title: In Vitro Anti-tumor Activity of Novel Nucleoside Analogs with an Optically Active Bicyclo Heptane Sugar Moiety
Dr. Tanase Constantin, Professor, National Institute for Chemical-Pharmaceutical Research & Development, Romania

Panel Discussion

18:30-20:30

Session Chair:

Keynote Speech
Title: Pharmaceutical Applications of Cyclotides: Macrocyclic Knotted Plant Proteins
Dr. David Craik, Professor, Institute for Molecular Bioscience, University of Queensland, Australia

Session Chair:

Title: Compounds that Affect the Activity of Hemichannels and or Gap Junction Channels as New Tolls to Modulate the Strength of Immune Responses
Dr. Juan C. Saez, Full Professor, Department of Physiological Sciences, Catholic University of Chile, Chile

Title: Advancements in Obesity Management: Adipocytokine-Based Drug Discovery
Dr. Nasser M. Al-Daghri, Assistant Professor, College of Science, Biochemistry Department, King Saud University, Kingdom of Saudi Arabia

Panel Discussion

Session Chair:

Co-Chair:

Keynote Speech
Title: The Use of Human Tissues for Biomarkers and Drug Discovery Research: Practical, Regulatory, and Ethical Concerns
Dr. Charles F. Saller, President & CEO, ABS, Inc., USA

Title: The Glycosphingolipid, Globotriaosyl Ceramide Provides New Therapeutic Approaches to Both Cancer Treatment and HIV Therapy
Dr. Clifford A. Lingwood, Hospital for Sick Children, Toronto, Canada

Title: Lysophosphatidic Acid Induces Ovarian Cancer Cell Migration via Activation of AMP-
Activated Protein Kinase
Dr. Pann-Ghill Suh, Professor, Department of Life Science, Postech, Korea

Title: A Human Tumor Genome Project: From Sequence to Structure, Function and Possibly Drug Targets
Dr. Peter W. Gunning, Head, Oncology Research Unit; Conjoint Professor, University of Sydney, Australia

Title: Integrating Biomarkers for Accelerated Drug Development--A Case Study of Dasatinib
Dr. Fei Huang, Associate Director, Oncology Clinical Biomarker, Bristol-Myers Squibb, USA

Title: PAK1 Interacts with* ?catenin and is Required for the Regulation of the ?catenin Signalling Pathway by Gastrins
Dr. Hong He, Senior Research Fellow, Department of Surgery University of Melbourne, Australia

Title: Novel Human Proteins-Future Drug Candidates for Controlling Human Immunodeficiency Virus (HIV)
Dr. Nitin Saksena, Head, Retroviral Genetics Division, Westmead Millennium Institute, Australia

Title: Transcription Factor Nrf2 as A Molecular Target for the Cytoprotection Against Oxidative Damage
Dr. Mi-Kyoung Kwak, Assistant Professor, School of Pharmacy, Lab of Pharmacology, Yeungnam University, South Korea

Session Chair:

Title: Drug Development to Cure Sleeping Sickness in Africa
Dr. Michael Duszenko, Professor, Department of Biochemistry University of Tuebingen, Germany

Title: Electrophoretic Separation of Hydrophobic Membrane Proteins Using Iso-electric Focusing
Dr. Kashino Yasuhiro, Assistant Professor, Graduate School of Life Science, University of Hyogo, Japan

Title: Physical Biotechnology Development and Its Biomedical Applications
Dr. Chunghsuan (Winston) Chen, Distinguished Research Fellow & Director, The Genomics Research Center, Taiwan

Session Chair:

Keynote Speech
Title: NF-kB Modulators in Osteolytic Bone Diseases
Dr. Jiake Xu, Associate Professor and Head, Molecular Orthopedic Lab, School of Surgery and Pathology, the University of Western Australia, Australia

Title:Estrogen Receptor Beta May be a Novel Target for the Beneficial Effects of Naturally-occurring Steroids, Therapeutics, and Selective Estrogen Receptor Modulators
Dr. Alicia A. Walf, Graduate Research Associate, University at Albany, USA

Title: Androgen Receptor and Its Coactivators in Prostate Cancer: Novel Targets for Androgen-independent Disease
Dr. Peng Lee, Assistant Professor of Pathology, NYU Langone Medical Center and VA New York Harbor Healthcare System, USA

Title: Progesterone and Its Metabolites as Therapeutic Targets
Dr. Cheryl A. Frye, Professor of Psychology, University at Albany, USA

Panel Discussion

Session Chair:

Title: Defining Organelle Proteomes
Dr. Rohan Teasdale, Group Leader, Institute for Molecular Bioscience, The University of Queensland, Australia

Title: Anticancer Drug Discovery Based on Zinc- dependent Metalloproteinase as Target
Dr. Wen-Fang Xu, Professor, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, China

Title: Protein Kinase D Signaling in Health and Disease
Dr. Johan Van Lint, Professor of Medical Biochemistry, Department of Molecular Cell Biology, Faculty of Medicine, Katholieke University Leuven, Belgium

Coffee Break

Session Chair:

Co-Chair:

Title: CU-0101, a Potent, Small Molecule, Multi-targeted Inhibitor of HDAC, EGFR and Her-2, Has Potent Antitumor Activity in vivo Xenograft Models
Dr. Cheng-Jung Lai, Director, Molecular and Cellular Oncology, Curis, Inc., MA, USA

Title: Treatment of Acute Pancreatitis: Targeting Inositol Trisphosphate Receptors
Dr. Ole H. Petersen, Professor, MRC Secretory Control Research Group, The Physiological Laboratory, University of Liverpool, UK

Title: Biomarker and Drug Discovery with High Density Functional Protein Microarrays
Dr. Timothy Wong, Regional Business Manager, Discovery Sciences & Proteomics, Asia Pacific Invitrogen Corporation, Hongkong, China

Panel Discussion

Session Chair:

Co-Chair:

Keynote Speech
Title: Hit Validation and Functional Selectivity Profiling Using ChemiscreenTM GPCR Cell Lines
Dr. Blaine N. Armbruster, Product Manager - GPCR Drug Discovery, Millipore Corp, USA

Title: In Silico and In Vitro Chemical Genomics Screens for GPCR Drug Discovery
Dr. Xiang-Qun (Sean) Xie,Professor, Dept of Pharmaceutical Sciences, School of Pharmacy; Drug Discovery Institute; Dept of Computational Biology and Structural Biology, University of Pittsburgh, USA

Title: Modern Molecular Modeling and Simulations to Explore Activation Pathways of G-Protein Coupled Receptors
Dr. Marta Filizola, Assistant Professor, Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, USA

Coffee Break

Title: A Confocal Fluorescence Imaging Method for High Throughput Drug Screening
Dr. Zhuan Zhou, Professor and Senior Investigator, Laboratory of Cellular Biophysics, Institute of Molecular Medicine, Peking University, China

Title: Exploring Adipocyte Expressed GPCRs as Potential Novel Therapeutics For Treating
Metabolic Diseases
Dr. Yang Li, Principal Scientist, Amgen Inc., USA

Title: Universal Structural Principles Applicable in Molecular Modeling of Integral Membrane Proteins
Dr. Siavoush Dastmalchi, Associate Professor, School of Pharmacy and Biotechnology Research
Center, Tabriz University of Medical Sciences, Iran

Session Chair:

Keynote Speech
Title: Optimize Your Clinical Data Management Using SAS Solutions
Mr. Jeff Sun, Sr. Technical Consultant, Global Health & Life Sciences, SAS Institute Inc., USA

Title: China Preclinical Services Outsourcing: Crouching Tiger Hidden Dragon
Dr. R. Stephen Porter, CSO, Medicilon/MPI Preclinical Research-Shanghai, USA

Title: Reporting Randomized Controlled Trials in Journal and Conference Abstracts
Dr. Giovanni Dondi dall'orologio, Associate Professor, Division of Conservative Dentistry
Department of Dental Sciences, University of Bologna, Italy

Title: Venturepharm a Full-Service Provider to World Pharmaceutical Life Science Industry
Dr. Song Xuemei, President of Venture Pharma Service (VPS) CRO Group, China

Coffee Break

Session Chair:

Title: A Novel Approach for the Screening of Psychotropic Drugs under Simulated Clinical Conditions
Dr. Natalia N. Kudryavtseva (Kudriavtseva), Head of Neurogenetics of Social Behavior Sector
in the Institute of Cytology and Genetics SD RAS, Russia

19:00-20:00

Session Chair:

Dr. Gert Storm, Professor, Utrecht University, The Netherlands

Co-Chair:

Dr. Kenichi Yoshikawa, Professor, Department of Physics, Kyoto University, Kyoto, Japan