BIT's 15th Annual Congress of International Drug Discovery Science and Technology - Japan 2017 (IDDST-Japan 2017)
★ Scientific Program

BIT's 15th Annual Congress of

International Drug Discovery Science and Technology - Japan 2017

Theme: Dedicated to Accelerating Drug Innovation

Time: July 25-27, 2017

Venue: Osaka, Japan

 

Keynote Forum Scientific Program
Section 1 Section 2 Section 3 Section 4 Section 5 Section 6 Young Scientist Forum

 

Section 6: From Disease Basic Science to Drug Development and Application
Session 601: Cancers/Tumors (Part I) - Basic Sciences
Day 1: Afternoon, Tuesday, July 25, 2017
13:00-17:30
Place: Yamato-A, 5F, Guest Room Tower, HRO
Chair: Dr. Shyng-Shiou F. Yuan, Professor and Director, Kaohsiung Medical University Hospital, Taiwan
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13:00-13:05 Chair's Introduction
13:05-13:30 Title: Epidemiology of Adult Acute Myeloid Leukemia: Impact of Exposures on Clinical Phenotypes and Outcomes after Therapy
Dr. Lisa Sproat,
Consultant and Assistant Professor of Medicine, Mayo Clinic Arizona, USA
13:30-13:55 Title: Complete Clinical Response of a Patient with Advanced Alpha-fetoprotein Producing Gastric Cancer Treated with Chemotherapy and Trastuzumab
Dr. Swei H. Tsung,
Chairman, Department of Patholgy, St Mary’s Hospital, Loudong, Yilan, Taiwan
13:55-14:20 Title: Alkaloids Mixture Increases Necrois and Tumor Regression in Pancreatic Ductal Adenocarcinoma (PDAC) in vitro and in vivo
Dr. Niccola Funel,
Principal Investigator, University of Pisa, Italy
14:20-14:45
Title: Sarcomatous Recurrence in Inflammatory Myofibroblastic Tumor
Dr. Yoen Young Chuah,
Attending Physician, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Ping Tung Christian Hospital, Taiwan
14:45-15:10 Title: The Synthetic β-nitrostyrene Derivative CYT-Rx20 Induces Breast Cancer Cell Death and Autophagy via ROS-mediated MEK/ERK Pathway
Dr. Shyng-Shiou F. Yuan,
Professor and Director, Kaohsiung Medical University Hospital, Taiwan
15:10-15:25 Coffee Break
15:25-15:50 Title: Biology of Cell-free Nucleic Acids and Its Role in Cancer Initiation and Metastasis
Dr. Indraneel Mittra,
Professor, Tata Memorial Centre, India
15:50-16:15 Title: The Role of Centrosome Over-duplication in Liver Cancer
Dr. Yick Pang Ching,
Associate Professor, The University of Hong Kong, Hong Kong, China
16:15-16:40 Title: Aryl hydrocarbon Receptor/MicroRNA Axis in Breast Cancer: Implications and Therapeutic Potential
Dr. Hamza Hanieh,
Associate Professor, King Faisal University, Saudi Arabia
16:40-17:05 Title: Mechanistic Studies of Intracellular Delivery of Molecules by Cell Penetrating Peptides in Human Lung Carcinoma A549 Cells
Dr. Betty R. Liu,
Assistant Professor, Laboratory Medicine and Biotechnology, Tzu Chi University, Taiwan
17:05-17:30   Title: Association of Single Nucleotide Polymorphism-2548 G/A (rs12112075) of Leptin Gene with Endometrial Cancer and Uterine Leiomyomas
Dr. Jan Bienkiewicz,
Resident in Obstetrics & Gynecology, Department of Surgical, Endoscopic Gynecology and Gynecologic Oncology, Polish Mothers' Memorial Hospital-Research Institute, Poland

 

Session 601: Cancers/Tumors (Part II) - Detection and Treatments
Day 2: Morning, Wednesday, July 26, 2017
08:30-12:35
Place: Yamato-A, 5F, Guest Room Tower, HRO
Chair: Dr. Y. Lynn Wang, Professor, The University of Chicago, USA
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08:30-08:35 Chair's Introduction
08:35-09:00 Title: Innovative Targeted Radiation Technology and Chemotherapy as a Means to Improve Cure Rate without Surgery for Patients with Rectal Cancer
Dr. Te Vuong,
Director, McGill University, Jewish General Hospital, Canada
09:00-09:25 Title: Ibrutinib Resistance and Exploration of Alternative Therapies Using a Personalized CLL Rx Model
Dr. Y. Lynn Wang,
Professor, The University of Chicago, USA
09:25-09:50
Title: Whole Liver Palliative Radiotherapy for Patients with Massive Liver Metastases
Dr. Edyta Wolny-Rokicka,
Head, Radiotherapy Department, Provincial Multidisciplinary Hospital in Gorzow Wielkopolski, Poland
09:50-10:15 Title: Evaluation of Cell Damaging Mechanisms Induced by Irradiated Zinc-Phthalocyanine-Gold Dendrimeric Particles Hybrid in a Breast Cancer Cell Line
Dr. Heidi Abrahamse,
Professor and Director, Laser Research Centre, University of Johannesburg, South Africa
10:15-10:30 Coffee Break
10:30-10:55 Title: Surgical Procedure of Neuroendocrine Carcinoma of the Bladder
Dr. Nikola Radovic,
Director, Urology Department, University Hospital Centre Zagreb, Croatia
10:55-11:20 Title: Pathogenetic Background of Hormonal Therapy for Malignant Ovarian Tumors
Dr. Iuliia G. Tkalia,
Oncogynecologist, National Cancer Institute, Ukraine
11:20-11:45 Title: Liquid Biopsy for EGFR Mutation-positive Lung Cancer
Dr. Kikuya Kato,
Professor, Nara Institute of Science and Technology, Japan
11:45-12:10 Title: Fluorescent L-glucose (fLG) as a Potential Contrast Agent for Cancer Detection
Dr. Katsuya Yamada,
Associate Professor, Hirosaki University, Japan
12:10-12:35   Title: Quantitative Ultrasound for Predicting and Monitoring Breast Cancer Chemotherapy
Dr. Gregory J. Czarnota,
Senior Scientist, Sunnybrook Research Institute, Canada
 

 

Session 601: Cancers/Tumors (Part III) - Cancer Immunotherapy
Day 2: Afternoon, Wednesday, July 26, 2017
13:00-16:40
Place: Yamato-A, 5F, Guest Room Tower, HRO
Chair: Dr. Jean-Francois Mirjolet, Technology Director, Oncodesign, France
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13:00-13:05 Chair's Introduction
13:05-13:30 Title: Advances in Biotherapeutics for Oncology
Dr. Shu-Hui Liu,
Director, Pfizer Inc., USA
13:30-13:55

Title: Preclinical Modeling in the Context of Precision Medicine in Oncology: Humanized Mouse Models
Dr. Jean-Francois Mirjolet,
Technology Director, Oncodesign, France

13:55-14:20 Title: Cancer Immunotherapy with Sequential Administration of Trabectedin and Nivolumab in Advanced Soft Tissue Sarcoma
Dr. Erlinda M. Gordon,
Director, Biological and Immunological Therapies, Sarcoma Oncology Center/Cancer Center of Southern California, USA
14:20-14:45 Title: Functional Roles of Cereblon (CRBN) and Argonaute 2 (AGO2) in Immunomodulatory Drug (IMiD) Induced Apoptosis
Dr. Xiu-bao Chang,
Consultant, Mayo Clinic Arizona, USA
14:45-15:10 Title: Antineoplastic Drug NSC631570 Changes Metabolic Profile of Tumor-Associated Microglia in Rats with C6 Glioma
Dr. Larysa Skivka,
Professor, Taras Shevchenko National University of Kyiv, Ukraine
15:10-15:25 Coffee Break
15:25-15:50 Title: Expression of MAGE-A and NY-ESO-1 Cancer/Testis Antigens in Tumors
Dr. Antonio Juretic,
Professor, Zagreb University Hospital Center, Croatia
15:50-16:15 Title: Rational Design and Validation of Immune Checkpoints Small Molecule Inhibitors: The PD-1 Example
Dr. Khaled Barakat,
Assistant Professor, University of Alberta, Canada
16:15-16:40 Title: Cytokines in the Tumor Pathophysiology. Therapeutic Intervention
Dr. Eva Kovacs-Benke,
Independent Researcher, Cancer Immunology Research, Switzerland

 

Session 601: Cancers/Tumors (Part IV) - Biologic Therapy
Day 3: Morning, Thursday, July 27, 2017
08:30-11:20
Place: Yamato-A, 5F, Guest Room Tower, HRO
Chair: Dr. Xiaoyan Jiang, Distinguished Scientist and Professor, BC Cancer Research Centre, Canada
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08:30-08:35 Chair's Introduction
08:35-09:00 Title: An Innovative Treatment Approach to Selectively Target Drug-resistant Leukemic Stem Cells
Dr. Xiaoyan Jiang,
Distinguished Scientist and Professor, BC Cancer Research Centre, Canada
09:00-09:25 Title: Targeting Cancer Stems Cells and Lung Metastasis
Dr. Yon Rojanasakul,
Distinguished Professor, West Virginia University, USA
09:25-09:50 Title: Vitamin D Receptor as a Potential Gene Therapy Target in Barrett's Esophagus and Esophageal Adenocarcinoma
Dr. Lydie Izakovicova Holla,
Professor, Masaryk University, Czech Republic
09:50-10:15 Title: EZH2-mediated Epigenetic Regulation of ROS1 Targets CXCL1 and GLI1 to Promote Invasiveness of Oral Cancer
Dr. Linyi Chen,
Professor, National Tsing Hua University, Taiwan
10:15-10:30 Coffee Break
10:30-10:55 Title: Oncolytic Virotherapy with Rigvir
Dr. Peteris Alberts,
Associate Professor, International Virotherapy Center, Latvia
10:55-11:20
Title: Coated Ferrite and Co-ferrite Nanoparticles for Combined Gene and Radiation Therapy
Dr. Stefanie Klein,
Postdoc, Friedrich-Alexander University Erlangen-Nuremberg, Germany

 

Session 601: Cancers/Tumors (Part V) - Anti-cancer Drugs
Day 3: Afternoon, Thursday, July 27, 2017
13:00-15:10
Place: Yamato-A, 5F, Guest Room Tower, HRO
Chair: Dr. Andrew D. Westwell, Professor, School of Pharmacy and Pharmaceutical Sciences, Cardiff University, UK
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13:00-13:05 Chair's Introduction
13:05-13:30 Title: Integrated Drug Discovery and Development Approach to Target Cancer
Dr. Bianca M. Liederer,
Senior Scientist, Genentech, Inc., USA
13:30-13:55 Title: The Discovery and Pre-clinical Development of a New Anti-metastatic Bcl3 Inhibitor
Dr. Andrew D. Westwell,
Professor, School of Pharmacy and Pharmaceutical Sciences, Cardiff University, UK
13:55-14:20 Title: The Proton Preparation NSC631570: The  Selective and Immunomodulating Effect of the  Anti-Cancer Preparation on Basis of Greater Celandine Alkaloids NSC631570
Dr. Wassil Nowicky,
Director, Nowicky Pharma; President of the Ukrainian Anti-Cancer Institute, Austria
14:20-14:45 Title: IGF-II and NSC-631570 Compounds Affect PMP22 Gene Expression in Pancreatic Ductal Adenocarcinoma. Could be the New Target for Both Chemo-resistance and Neuronal Invasion?
Dr. Niccola Funel,
Principal Investigator, University of Pisa, Italy
14:45-15:10 Title: Enhanced Antitumor Effects of Novel Intracellular Delivery of an Active Form of Menaquinone-4, Menahydroquinone-4, into Hepatocellular Carcinoma
Dr. Kazuhisa Matsunaga,
Associate Professor, Fukuoka University, Japan
15:10-15:25 Coffee Break

 

Session 602: CNS Diseases
Day 1: Afternoon, Tuesday, July 25, 2017
13:00-17:55
Place: Yamato-B, 5F, Guest Room Tower, HRO
Chair: Dr. Gayathri Ramaswamy, Lab Head and Senior Principal Scientist, Internal Medicine Research Unit, Pfizer Inc., USA
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13:00-13:05 Chair's Introduction
13:05-13:30 Title: A Novel Mechanism for Increasing Brain Apolipoprotein E Levels
Dr. Gayathri Ramaswamy,
Lab Head and Senior Principal Scientist, Internal Medicine Research Unit, Pfizer Inc., USA
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13:30-13:55 Title: Genetically Encoded Light-sensitive Amino Acids Uncover Allosteric Regulation in Neuronal Receptors
Dr. Shixin Ye-Lehmann,
Principle Investigator, Laboratory of Computational and Quantitative Biology, University of Pierre Marie Curie, France
13:55-14:20 Title: Novel Long Acting Injectable Medications: A Challenge to Drug Discovery and the Recovery Model in Psychiatry
Dr. Peter Norrie,
Director of Clinical Services, Justice Health and Alcohol & Drug Services, ACT Health, Australia
14:20-14:45 Title: Effects of Glycine and D-cycloserine on in vivo Neuronal Activity in Normal and Schizophrenia Model Mice
Dr. Qiang Zhou,
Professor and Associate Dean, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, China
14:45-15:10 Title: Pharmacological Approach to Neurodevelopment Disorders in a Mouse Model of Autism
Dr. Maurizio Memo,
Professor, University of Brescia, Italy
15:10-15:25 Coffee Break
15:25-15:50 Title: Alteration in Protein Synthesis Machinery Contributes to Overexpression of APP Full Length is the Hippocampus of Tg2576 Mice and Sporadic Alzheimer Patients
Dr. Martine Ammassari-Teule,
Research Director, CNR-National Research Council, Italy
15:50-16:15 Title: PTEN as a Molecular Target for Alleviating Cognitive Defects in a Mouse Model of Alzheimer’s Disease
Dr. Andrew M. Chan,
Professor and Chief, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
16:15-16:40 Title: Multifunctional Liposomes for Treatment and Prevention of Alzheimer Disease: An All-in-one Nanomedicine
Dr. Massimo Masserini,
Director, Nanomedicine Center, University Milano Bicocca, Italy
16:40-17:05 Title: Pulse Blood Pressure Correlates with Late Outcome in Acute Ischemic Stroke without Significant Culprit Artery Stenosis
Dr. Po-Lin Chen,
Director of Stroke Center, Taichung Veterans General Hospital, Taiwan
17:05-17:30 Title: Platelets Regulate Neuroinflammation and Neuronal Functions during Brain Injury
Dr. Eugene D. Ponomarev,
Assistant Professor, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
17:30-17:55 Title: Recovery of an Immunocompetent Adult Patient from a Possible Cytomegalovirus Meningoencephalitis-induced Brain Stem Death
Dr. Theresia Monica Rahardjo,
Anesthesiologist, Maranatha Christian University, Indonesia

 

Session 603: Circulatory System and Respiratory System Diseases
Day 2: Morning, Wednesday, July 26, 2017
08:30-12:35  
Place: Yamato-B, 5F, Guest Room Tower, HRO
Chair: Dr. Aouatef Bellamine, Senior Scientific Manager, Lonza Inc., USA
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08:30-08:35 Chair's Introduction
08:35-09:00 Title: L-Carnitine Intake and High Trimethylamine N-oxide Plasma Levels Correlate with Low Aortic Lesions in Apoe-/-Transgenic Mice Expressing CETP
Dr. Aouatef Bellamine,
Senior Scientific Manager, Lonza Inc., USA
09:00-09:25 Title: End-organ Protection in Hypertension and Diabetes by the Novel and Selective Rho-kinase Inhibitor, SAR407899
Dr. Matthias Loehn,
Senior Scientist, Sanofi R&D, Germany
09:25-09:50 Title: Signaling in the Mechanically-loaded Cardiomyocyte: Implications for Drug Discovery
Dr. Leighton T. Izu,
Associate Professor, University of California, Davis, USA
 
09:50-10:15 Title: Comparison of Transtracheal Pressure in Children Wearing Speaking Valve While Awake and Asleep
Dr. Melodi Pirzada,
Clinical Associate Professor, NYU Winthrop Hospital, USA
10:15-10:30 Coffee Break
10:30-10:55 Title: Neointimal Hyperplasia in Dialysis Vascular Accesses
Dr. Moro O. Salifu,
Chair, Department of Medicine, State University of New York Downstate Medical Center, USA
10:55-11:20 Title: The Chemosensory Impact of Bitter Tastants on the Autonomic and Cardiovascular Systems
Dr. Michael K McMullen,
Owner, MCMULLEN AB, Sweden
11:20-11:45 Title: Prominent Hyperplasia of Renin-producing Juxtaglomerular Apparatus after Chronic and Complete Blockade of the Renin Angiotensin System in Adult IgA Nephropathy
Dr. Michiaki Abe, Associate Professor, Tohoku University Hospital, Japan
11:45-12:10 Title: Is High High-density Lipoprotein Cholesterol Beneficial for Premature Coronary Heart Disease? A Meta-analysis
Dr. Runlu Sun,
Physician, Cardiovascular Department, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China
12:10-12:35 Title: Interstitial Lung Disease (ILD) in India: Prospective Registry of 1084 Patients 2012-2016
Dr. Rajesh Swarnakar,
Director, Getwell Hospital & Research Institute, India

 

Session 604: Metabolic Disorders (Part I) - Basic Sciences and Epidemiology of Diabetes
Day 2: Morning, Wednesday, July 26, 2017
08:30-11:45  
Place: Yoshino, 5F, Guest Room Tower, HRO
Chair: Dr. Shaodong Guo, Associate Professor, Texas A&M University, USA
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08:30-08:35 Chair's Introduction
08:35-09:00 Title: Diabetes Mellitus: Disorder of Cellular Dysfunction Due to Lack of Entry into Cell of Glucose; The Most Efficient Fuel for Cellular Function
Dr. Udaya M. Kabadi,
Adjunct Professor, University of Iowa, USA
09:00-09:25 Title: Insulin Receptor Substrate Signaling Controls Cardiac Energy Metabolism and Heart Failure
Dr. Shaodong Guo,
Associate Professor, Texas A&M University, USA
09:25-09:50 Title: Ratio of Dietary ω-3 and ω-6 Fatty Acids-independent Determinants of Muscle Mass-in Hemdialysis Patients with Diabetes
Dr. Shwu-Huey Sherry Yang,
Associate Professor, Taipei Medical University, Taiwan
09:50-10:15 Title: HLA-DR, HLA-DQ Haplotypes and Diabetic Autoantibodies in Nondiabetic Siblings of Type I Diabetes
Dr. Sitelbanat Awadalla,
Associate Professor, King Saud Bin Abdelaziz University, Saudi Arabia
10:15-10:30 Coffee Break
10:30-10:55 Title: Managing Complex and Disengaged Patients in Primary Care. What Can Pharmaceutical Companies Learn from New Delivery of Care?
Dr. Waqar Malik,
Consultant Diabetologist, Birmingham Community Healthcare Trust / Birmingham Heartland Hospital, UK
10:55-11:20 Title: Diabetes Mellitus in Myanmar: Socio-cultural Challenges and Strength
Dr. Than Than Aye,
President, Myanmar Society of Endocrinolgy and Metabolism, Myanmar
11:20-11:45 Title: Obesity and Diabetes in Asian Women: Cultural Caveats
Dr. Hana Al-Bannay,
Instrutor, New York University Abu Dhabi, United Arab Emirates

 

Session 604: Metabolic Disorders (Part II) - Diabetes Treatments and Drugs
Day 2: Afternoon, Wednesday, July 26, 2017
13:00-15:35  
Place: Yoshino, 5F, Guest Room Tower, HRO
Chair: Dr. Moon K. Song, Principal Investigator, VA Greater Los Angeles Healthcare System, USA
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13:00-13:05 Chair's Introduction
13:05-13:30 Title: Adaptive Artificial Pancreas Improves Night Glucose Control in Free-living Conditions in Subjects with Type 1 Diabetes
Dr. Lalo Magni,
Dean of Engineering Faculty, University of Pavia, Italy
13:30-13:55 Title: Telemedicine Compared with Standard Care in Type 2 Diabetes Mellitus: A Randomized Trial in an Outpatient Clinic
Dr. Ole Winther Rasmussen,
Associate Professor, Medical Department, Kolding Hospital, Denmark
13:55-14:20 Title: Modeling Heterogeneity on the Effect of Statins in Patients at Risk of Developing Diabetes
Dr. Pedro J. Caraballo,
Associate Professor, Mayo Clinic, USA
14:20-14:45 Title: Improvement of Insulin Sensitivity by the Treatment with Cyclo (his-pro) Plus Zinc in Humans
Dr. Moon K. Song,
Principal Investigator, VA Greater Los Angeles Healthcare System, USA
14:45-15:10 Title: TYK2 Promoter Variant and Diabetes Mellitus in the Japanese-susceptibility Gene Study in Virus-induced Diabetes will Lead to the Development of Anti-daibetogenic Virus Vaccine
Dr. Seiho Nagafuchi,
Professor Emeritus, Kyushu University, Japan
15:10-15:35 Title: Can Liraglutide be the First-line Therapy for Japanese Patients with Type 2 Diabetes?
Dr. Yoshifumi Saisho,
Assistant Professor, Department of Internal Medicine, Keio University School of Medicine, Japan

 

Session 604: Metabolic Disorders (Part III) - Obesity
Day 3: Morning, Thursday, July 27, 2017
10:50-12:35  
Place: Tatsuta, 5F, Guest Room Tower, HRO
Chair: Dr. Edy Soffer, Professor and Director, University of Southern California, USA
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10:50-10:55 Chair's Introduction
10:55-11:20 Title: Gastric Electrical Stimulation for Obesity
Dr. Edy Soffer,
Professor and Director, University of Southern California, USA
11:20-11:45

Title: Current Pharmacotherapy of Obesity Management. How Can We Educate the Trainees?
Dr. Mukta Panda,
Professor and Assistant Dean, University of Tennessee, USA
Dr. Jennifer Dooley, Clinical Assistant Professor and Program Director, University of Tennessee, USA

11:45-12:10 Title: The Obesity and Central Pressure in  Aspect of Preventive Examinations of Student's Youth
Dr. Maria Evsevyeva,
Professor, Stavropol State Medical University, Russia
12:10-12:35 Title: Leptin Replacement Therapy in Lipodystrophy
Dr. Vinaya Simha,
Assistant Professor, Department of Endocrinology, Mayo Clinic, USA
 

  

Session 604: Metabolic Disorders (Part IV) - Other Metabolic Disorders
Day 3: Afternoon, Thursday, July 27, 2017
13:00-16:15  
Place: Yoshino, 5F, Guest Room Tower, HRO
Chair: Dr. Chaodong Wu, Associate Professor, Texas A&M University, USA
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13:00-13:05 Chair's Introduction
13:05-13:30 Tilte: The Intestinal Microbiome, Metabolic Diseases and Probiotics
Dr. Luis Vitetta,
Director of Medical Research, Medlab Clinical Pty Ltd., Australia
13:30-13:55 Title: Involvement of AMPK in the Beneficial Effects of Metformin
Dr. Chaodong Wu,
Associate Professor, Texas A&M University, USA
13:55-14:20 Title: Development of Sodium Pyruvate Therapy for Lactic Acidosis Associated with Mitochondrial Disorders
Dr. Yasutoshi Koga,
President, Japanese Society of Mitochondrial Research and Medicine; Professor, Kurume University Graduate School of Medicine, Japan
14:20-14:45 Title: Recent Understanding on Non-alcoholic Fatty Liver Disease
Dr. Kaori Minehira,
Project Manager, University of Lausanne, Switzerland
14:45-15:10 Title: Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co-morbidities Linked to Polycystic Ovary Syndrome (PCOS)
Dr. Jennifer Phy,
Associate Professor, Texas Tech University Health Sciences Center, USA
15:10-15:25 Coffee Break
15:25-15:50 Title: Diagnosis and Management of Growth Disorders in Gulf Cooperation Council (GCC) Countries: Current Procedures and Key Recommendations for Best Practice
Dr. Abdullah Al Herbish,
Vice President, Physician Affairs, Dr. Sulaiman Al Habib Medical Group, Saudi Arabia
15:50-16:15 Title: Cardiovascular Protection by Ezetimibe and Influence on Oxidative Stress in Mice Exposed to Intermittent Hypoxia
Dr. Ryuji Kato,
Lecturer, Laboratory of Cardiovascular Pharmacotherapy and Toxicology, Osaka University of Pharmaceutical Sciences, Japan

 

Session 605: Infectious Diseases and Infections (Part I) - Basic Sciences and Epidemiology
Day 2: Morning, Wednesday, July 26, 2017
08:30-12:35   
Place: Mai, 2F, Banquet Tower, HRO 
Chair: Dr. Lisa A. George, Clinical Director and Lead Clinician, Crossroads to Health and Recovery Clinic, Community Alliance; Faculty, College of Nursing Doctoral Program, Creighton University, USA
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08:30-08:35 Chair's Introduction
08:35-09:00 Title: New Tools in Preclinical Drug Development for Tuberculosis
Dr. Anne J. Lenaerts,
Professor, Colorado State University, USA
09:00-09:25 Title: Management of Skin and Soft Tissue Infections in a County Correctional Center: A Quality Improvement Project
Dr. Lisa A. George,
Clinical Director and Lead Clinician, Crossroads to Health and Recovery Clinic, Community Alliance; Creighton University, USA
09:25-09:50

Title: Autopsy Findings in 15 Children Who Died Following Klebsiella Pneumoniae Bloodstream Infection at Red Cross War Memorial Children’s Hospital, Cape Town: 2006-2011
Dr. Heloise Buys,
Head of Clinical Unit, University of Cape Town, South Africa

 
09:50-10:15

Title: Current Hepatitis B Virus Infection Situation in Indonesia, An Endemic Country
Dr. Maria Inge Lusida,
Director, Institute of Tropical Disease, Airlangga University, Indonesia

10:15-10:30 Coffee Break
10:30-10:55

 

Title: The Role of Healthcare Providers in Translational Research among Academician, Industry, Government, and Community. A Case of Rotavirus Vaccine Development
Dr. Yati Soenarto,
Professor of Pediatrics, Gadjah Mada University, Indonesia

 

10:55-11:20 http://www.dnaday.com/images/psp/no.jpg Title: MicroRNAs are Potential Therapeutic Targets and Biomarkers for Alveolar Bone Loss in Periodontal Disease
Dr. Tadayoshi Kagiya,
Assistant Professor, Iwate Medical University, Japan
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11:20-11:45 Title: Successful Unrelated Cord Blood Stem Cell Transplantation in an X-linked Chronic Granulomatous Disease Patient with Disseminated BCG-induced Infection
Dr. Chao-Jen Lin,
Attending Physician, Changhua Christian Children’s Hospital, Taiwan
11:45-12:10 Title: Resiniferatoxin Lowers TNF-α, NO and PGE2 in the Intestinal Phase and the Parasite Burden in the Muscular Phase of T. Spiralis Infection
Dr. Jose Luis Munoz-Carrillo,
Researcher, Laboratory of Cell Biology and Microbiology, Academic Unit of Biological Sciences, Autonomous University of Zacatecas, Mexico
12:10-12:35 Title: Diffusion Exponent in Virus Infection Pathway: Fluctuations and Deviation
Dr. Yuichi Itto,
Lecturer, Aichi Institute of Technology, Japan

 

Session 605: Infectious Diseases and Infections (Part II) - Diagnosis and Secondary Diseases
Day 2: Afternoon, Wednesday, July 26, 2017
15:45-17:55   
Place: Yoshino, 5F, Guest Room Tower, HRO 
Chair: Dr. Gerhard Jahn, Medical Director, Institute for Medical Virology and Epidemiology of Viral Disease, University Hospital of Tubingen, Germany
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15:45-15:50 Chair's Introduction
15:50-16:15 Title: Comprehensive Molecular Tests in Bioprocessing
Dr. Roger Hodkinson,
Director, MultiGEN Diagnostics, USA
16:15-16:40 Title: The Importance of Establishing a Differential Diagnosis in Vesicular Diseases (HSV Infections, Dyshidrosis, Impetigo)
Dr. Hana Zelenkova,
Founder, Private Clinic of  Dermatovenerology - DOST Svidnik, Slovakia
16:40-17:05 Title: The Impact of Primary vs. Secondary Infection of HCMV in Pregnancy for the Outcome of the Newborn
Dr. Gerhard Jahn,
Medical Director, Institute for Medical Virology and Epidemiology of Viral Disease, University Hospital of Tubingen, Germany
17:05-17:30

Title: Clinically Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion Caused by Infection
Dr. Tsuneaki Kenzaka,
Professor, Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Japan
Dr. Koki Kosami, Chief Physician, Department of Internal Medicine, Asago Medical Center, Japan

17:30-17:55

Tilte: Analysis of Correlation between Inflammatory Parameters and Severity of Sepsis Caused by Bacterial Bloodstream Infection in Septic Patients
Dr. Lei Zhao,
Attending Doctor, Beijing Shijitan Hospital, China

 

 

Session 605: Infectious Diseases and Infections (Part III) - Antibacterial Drug
Day 3: Morning, Thursday, July 27, 2017
08:30-11:45   
Place: Yoshino, 5F, Guest Room Tower, HRO
Chair: Dr. Christian van Delden, Professor, Geneva University Hospital, Switzerland
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08:30-08:35 Chair's Introduction
08:35-09:00

Title: Discovery and Clinical Development of Cefidercol, A Novel Siderophore Cephalosporin, for the Treatment of the Infection Caused by Multi-drug Resistant Gram-negative Bacteria
Dr. Yoshinori Yamano,
Chief Scientific Officer for Infectious Diseases, Shionogi & Co., Ltd., Japan

09:00-09:25 Title: Comparative Activity of an Advanced Generation Fluoroquinolone, Acorafloxacin, Versus Commercial Ophthalmic Fluoroquinolones against Susceptible and Resistant Ocular Pathogens
Dr. Terrence P. O’Brien,
Professor of Ophthalmology and Charlotte Breyer Rodgers Distinguished Chair, University of Miami, USA
09:25-09:50 Title: New Therapeutic Approches against Pseudomonas Aeruginosa
Dr. Christian van Delden,
Director, Transplant Infectious Diseases Unit, University Hospitals Geneva, Switzerland
09:50-10:15 Title: Development of Probiotics Expressing Antimicrobial Immunomodulatory Peptides: A New Strategy in the Development of Enteral Nutritional Therapies
Dr. Octavio Luiz Franco,
Professor, Dom Bosco Catholic University, Brazil
10:15-10:30 Coffee Break
10:30-10:55 Title: Mode of Action of Novel Antimicrobial Peptides
Dr. Surajit Bhattacharyya,
Associate Professor, Nanyang Technological University, Singapore
10:55-11:20 Title: To Differentiate Significant Infection or Colonization: Essential for Preauthorisation and Prospective Audit to Optimize Treatment and Assist Antimicrobials Stewardship Programs (ASWPs)
Dr. Khine Swe Swe Han,
Pathologist, University of KawaZulu Natal (UKZN) and National Health Laboratory Service (NHLS), South Africa
11:20-11:45 Title: Probiotics at a Lower Dose in Very Low Birth Weight Infants - Are They Safe and Still Effective?
Dr. Zlatka Kanic,
Pediatric Intensivecare Specialist, Intensivecare Unit, Division of Paediatrics, University Medical Centre Maribor, Slovenia

 

Session 605: Infectious Diseases and Infections (Part IV) - Antiviral and Antiparasite Drug
Day 3: Afternoon, Thursday, July 27, 2017
15:25-17: 35   
Place: Yamato-A, 5F, Guest Room Tower, HRO
Chair: Dr. Mark Broenstrup, Professor, Helmholtz Centre for Infection Research, Germany
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15:25-15:30 Chair's Introduction
15:30-15:55 Title: Chemical Biology Directed to Anti-infective Drug Discovery
Dr. Mark Broenstrup,
Professor, Helmholtz Centre for Infection Research, Germany
15:55-16:20

Title: Role of Artificial miRNAs against Viral Genes in Inhibition of HSV-1 Productive and Latent Infections
Dr. Grace Zhou,
President, Shenzhen International Institute for Biomedical Research, China

16:20-16:45 Title: Influensa Drug Discovery and Synthesis as the Neuraminidase Inhibitor
Dr. Tomoko Mineno,
Associate Professor, Takasaki University of Health and Welfare, Japan
16:45-17:10 Title: Accelerating Anti-malaria Drug Discovery Using Novel Phenotypic Screening Platforms: From Bench to Industry
Dr. Kevin S. W. Tan,
Associate Professor, National University of Singapore, Singapore
17:10-17:35

 

Title: New β-Carbolines as Potential Antiprotozoal Agents for Treatment of Leishmaniasis and Chagas Disease
Dr. Celso Vataru Nakamura,
Associate Professor, State University of Maringa, Brazil

 

Session 606: Digestive System Diseases (Part I) - Gastrointestinal Diseases
Day 3: Morning, Thursday, July 27, 2017
08:30-11:45   
Place: Yamato-B, 5F, Guest Room Tower, HRO
Chair: Ms. Leticia Delgado-Herrera, Executive Director, Astellas Pharma Global Development, USA
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08:30-08:35 Chair's Introduction
08:35-09:00 Title: Development of a Patient - Reported Outcome Measure of Diarrhea-predominant Irritable Bowel Syndrome (IBS-D) Symptoms
Ms. Leticia Delgado-Herrera,
Executive Director, Astellas Pharma Global Development, USA
09:00-09:25 Title: The Dietary Fiber Supplementation in the Management of Irritable Bowel Syndrome
Dr. Magdy El-Salhy,
Professor, University of Bergen, Norway
09:25-09:50 Title: Haemorhoidectomy: Avoiding Tamponade Leads to Pain Reduction in Clinical Randomised Trial
Dr. Mike Ralf Langenbach,
Clinical Director, Helios St. Elisabeth Hospital in Oberhausen, Germany
09:50-10:15 Title: Ethnic/Racial Differences in Helicobacter Pylori Infection: Relationship with Gastrointestinal Symptoms, Anxiety, Stress, and Personal Behaviors
Dr. Maria-Raquel Huerta-Franco,
Professor, University of Guanajuato, Mexico; University of Missouri in Kansas, USA

10:15-10:30 Coffee Break
10:30-10:55 Title: An Association between Unrecognized Gastroesophageal Reflux Disease and Excessive Daytime Sleepiness in Taiwanese Subjects Suspected to Have Liver Disease: A Pilot Study
Dr. Jing-Hong Hu,
Director, Department of Internal Medicine, Yunlin Chang-Gung Memorial Hospital, Taiwan
10:55-11:20 Title: Validation of a New Method for the Endoscopic Measurement of Post-bariatric Gastric Outlet Using a Standard Guidewire: An Observer Agreement Study
Dr. Roberto Luiz Kaiser Junior,
Director, Kaiser Clinic & Day Hospital, Brazil
11:20-11:45 Title: Ebstein-Barr Virus Infection Associated Gastrointestinal Manifestations
Dr. Wendy Jie-Ying Wu, 
Visiting Staff, Taipei Medical University Shuang-Ho Hospital, Taiwan

 

Session 606: Digestive System Diseases (Part II) - Hepatobiliary and Pancreatic Diseases
Day 3: Afternoon, Thursday, July 27, 2017
13:00-16:15   
Place: Yamato-B, 5F, Guest Room Tower, HRO
Chair: Dr. Naoki Hashimoto, Professor, Department of Surgery, Kindai University, Japan
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13:00-13:05 Chair's Introduction
13:05-13:30 Title: Rabeprazole is Effective for Bile Reflux Esophagitis after Total Gastrectomy in a Rat Model
Dr. Naoki Hashimoto,
Professor, Department of Surgery, Kindai University, Japan
13:30-13:55 Title: Hepcidin Protects against Lipopolysaccharide-induced Liver Injury in a Mouse Model of Obstructive Jaundice
Dr. Ying-Hsien Huang,
Associate Professor, Kaohsiung Chang Gung Memorial Hospital, Taiwan

13:55-14:20

Title: Diagnostic Challenges of Biliary Atresia: Back to Missed Basic Science
Dr. Ahmad Sira,
Associate Professor, National Liver Institute, Menofiya University, Egypt

14:20-14:45 Title: Decellularized Cattle Placentome as a Natural Three-dimensional Scaffold for Creating Functional Hepatic-like Tissue in vivo
Dr. Zurab Kakabadze,
Head, Department of Clinical Anatomy, Tbilisi State Medical University, Georgia
14:45-15:10 Title: Creating Three-dimensional Bone Scaffold, Seeding It with Freeze-dried Bone Marrow Stem Cells
Dr. David Chakhunashvili,
Assistant Professor, Department of Clinical Anatomy, Tbilisi State Medical University, Georgia
15:10-15:25 Coffee Break
15:25-15:50 Title: Portal Vein Thrombosis in Liver Graft Ten Years After Liver Transplantation Due to Budd-Chiari Syndrome
Dr. Azra Husic-Selimovic,
Associate Professor, University of Sarajevo, Bosnia and Herzegovina
15:50-16:15 Title: Clinical Trial Proposing a New Combination for Treatment in NAFLD/NASH Involving Intestinal Microbiota in the Pathophysiology of Liver Inflammation and Bile Acids Metabolism
Dr. Adriana Popescu,
Assistant Professor, Clinical Institute Fundeni, Romania

 

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