Program
Time: May 22-24, 2024
Venue: Grand Prince Hotel Osaka Bay, Osaka, Japan
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Registration Time: 09:00-21:00, May 21, 2024 (Tuesday); Place: Public Space, 5F, Grand Prince Hotel Osaka Bay |
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Opening Ceremony Time: 09:00-09:10, May 22, 2024 (Wednesday); Place: Crystal & Ruby, 2F, Grand Prince Hotel Osaka Bay |
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Keynote Forum Time: 09:10-11:45, May 22, 2024 (Wednesday); Place: Crystal & Ruby, 2F, Grand Prince Hotel Osaka Bay |
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Moderator |
Dr. Matthias von Herrath, Scientific Director of the Diabetes Research Institute, University of Miami School of Medicine; Vice President, Novo Nordisk, USA |
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09:10-09:15 |
Moderator's Introduction |
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09:15-09:40 |
Title: New Era of Discovery Chemistry Dr. Muneto Mogi, Global Head, Global Discovery Chemistry, Novartis Institutes for BioMedical Research (NIBR), USA |
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09:40-10:05 |
Title: Innovative Chemistry for Pharmaceutical Development Dr. Jeff Song, Vice President, Boehringer Ingelheim Pharmaceuticals, Inc, USA |
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10:05-10:30 |
Title: Pathology of T1D and New Treatment Options Dr. Matthias von Herrath, Vice President and Senior Medical Officer, Novo Nordisk, USA |
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10:30-10:55 |
Title: Continuous Manufacturing of Complex Parenterals such as mRNA Vaccines and Liposomes Dr. Diane J. Burgess, Distinguished Professor and Pfizer Distinguished Chair of Pharmaceutical Technology, University of Connecticut, USA |
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10:55-11:20 |
Title: Pharmacological Profile of Deucrictibant, A Small-molecule Bradykinin B2 Receptor Antagonist in Clinical Development for Hereditary Angioedema Dr. Anne S.J. Lesage, Chief Early Development Officer, Pharvaris GmbH, Switzerland |
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11:20-11:45 |
Title: Eisai’s Quantitative Systems Pharmacology (QSP) Alzheimer’s Disease (AD) Platform: A Tool for Gaining Mechanistic Insight and Generating Testable Hypotheses Dr. Antonio Cabal, Sr. Director, Biology Based Modeling & Simulation, Eisai Inc., USA |
The 20th Annual Congress of International Drug Discovery Science & Technology (IDDST-2024)
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IDDST 01: Novel Analytical & Breakthrough Technology in Drug Discovery Time: 13:30-16:45, May 22, 2024 (Wednesday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Kiyoshi Nokihara, Founder and CEO/CSO, HiPep Laboratories, Japan |
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13:30-13:35 |
Chair's Introduction |
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13:35-14:00 |
Session Keynote Speech Title: Motile and Deformable RNA Nanoparticles Enable both Spontaneous Tumor Targeting with Undetectable Toxicity Dr. Peixuan Guo, Endowed Chair and Director, The Ohio State University, USA |
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14:00-14:25 |
Title: High-Throughput Sequence Determination of On-Bead Cyclic Peptide Libraries for Discovery of Medicinal Molecules Dr. Kiyoshi Nokihara, Founder and CEO/CSO, HiPep Laboratories, Japan |
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14:25-14:50 |
Title: Illuminating Drug Discovery with Bioluminescent Assays Dr. Frank Fan, Head of Biology, Promega Corporation, USA |
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14:50-15:15 |
Title: Selective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models Dr. Guang Zhu, Professor, Hong Kong University of Science and Technology, Hong Kong, China |
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15:15-15:30 |
Coffee Break |
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15:30-15:55 |
Title: Photodynamic Antimicrobial Function of Carbon Dots Dr. Liju Yang, Professor, North Carolina Central University, USA |
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15:55-16:20 |
Title: Biosensors Integrated in Biological Models for Drug Discovery and Early Diagnosis Dr. Monica Mir, Senior Researcher, Institute for Bioengineering of Catalonia, Spain |
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Title: Microphysiological Systems: In Vitro Tools for Safety, Efficacy and Precision Medicine Dr. Danilo A. Tagle, Director, National Institutes of Health, USA |
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IDDST 02: Breaking Preclinical Research Time: 13:30-17:10, May 22, 2024 (Wednesday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. John Renger, Chief Scientific Officer, Cerevel Therapeutics, USA |
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13:30-13:35 |
Chair's Introduction |
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13:35-14:00 |
Title: Pre-clinical Development of a CD8 Selective T Cell Engager for Autoimmune Disease and Cacer Dr. Xiaoqiang Yan, Founder, Chairman & CEO, ITabMed Ltd., China |
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14:00-14:25 |
Title: A Novel Humanized Anti-Secreted Glycoprotein YKL-40 Antibody: Potential for Cancer Therapy Dr. Rong Shao, Professor, Department of Pharmacology, Shanghai Jiao Tong University School of Medicine, China |
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14:25-14:50 |
Title: Identification of TMEM175 Small Molecule Activators as Candidate Disease-Modification Therapeutics for Parkinson Disease Dr. John Renger, Chief Scientific Officer, Cerevel Therapeutics, USA |
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14:50-15:15 |
Title: Uncovering New Avenues to Triumph Over Chemoresistance in Solid Tumors Dr. Xiaonan Zhang, Associate Professor, Uppsala University, Sweden |
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15:15-15:30 |
Coffee Break |
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15:30-15:55 |
Title: Onco-target SET/Taf1β Precisely Fine-tunes Chromosome Segregation in the Inner Centromere Dr. Yuichiro Asai, Assistant Manager, KONICA MINOLTA, INC., Japan |
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15:55-16:20 |
Title: Allosteric Ubiquitin E3-ligase Inhibitor for the Treatment of PAH, Autism and Other Diseases Dr. Gali Prag, Professor, Tel Aviv University, Israel |
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16:20-16:45 |
Title: Targeting Human MrgprX1 for the Treatment of Neuropathic Pain Dr. Takashi Tsukamoto, Professor of Neurology, Johns Hopkins School of Medicine, USA |
| 16:45-17:10 |
Title: Exploring the Takeout Food Preferences and Interactions with Demographic Characteristics in China: A Discrete Choice Experiment in Chinese Adults Dr. Shanquan Chen, Assistant Professor, Chinese University of Hong Kong, Shenzhen, China |
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IDDST 03: Clinical Trials, Pharmacovigilance, Drug Safety and Risk Management Time: 13:30-16:45, May 22, 2024 (Wednesday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Lin Zhang, Professor of Neurology, UCDavis School of Medicine, USA |
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13:30-13:35 |
Chair's Introduction |
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13:35-14:00 |
Title: A Novel Compound Chimeric Antigen Receptor for Treatment of Autoimmune Diseases Dr. Nabil Hagag, Director of Cellular Therapies, Stony Brook Medicine, USA |
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14:00-14:25 |
Title: Early Diagnosis of Neurodegenerative Disorders with Biomarkers Dr. Lin Zhang, Professor of Neurology, UCDavis School of Medicine, USA |
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14:25-14:50 |
Title: Radiation-Enhancement of Breast Tumours Through Ultrasound Stimulated Microbubble Treatment - Phase 1 Clinical Trial Results Dr. Gregory J. Czarnota, Professor, University of Toronto, Canada |
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14:50-15:15 |
Title: Established Safety of Human Serum Albumin in Aesthetic Botulinum Toxin Formulations Dr. Andrew Curry, Associate Global Medical Director, Global Medical Affairs, Merz Aesthetics, USA |
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15:15-15:30 |
Coffee Break |
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15:30-15:55 |
Title: Effects of Rosa Canina L Subspecies (Lito) on Joint Pain, Daily Activities and the Consumption of Rescue Medication in Osteoarthritis with Some References to Weight Loss Dr. Kaj Winther, Professor, University of Copenhagen, Denmark |
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15:55-16:20 |
Title: Medication Review 2.0, A New Approach to Reduce Medication-related Harm in a Clinical Setting Dr. Michiel A. van Agtmael, Professor, VU University Medical Center, the Netherlands |
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16:20-16:45 |
Title: Ensuring Perioperative and PACU Drug Safety Dr. Amballur David John, Assistant Professor of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, USA |
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IDDST 04: Cancers/Tumors Time: 13:30-17:10, May 22, 2024 (Wednesday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Ella L. Kim, Laboratory Director, Johannes Gutenberg University Medical Centre Mainz, Germany |
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13:30-13:35 |
Chair's Introduction |
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13:35-13:55 |
Title: Unlocking the Epigenetic Code in Cancer for Novel Therapeutics Dr. Yali Dou, Professor of Medicine, Marion and Harry Keiper Chair in Cancer Research, University of Southern California, USA |
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13:55-14:15 |
Title: Homologous and Heterologous Fusion of Cancer Stem Cells: A Potential Hallmark of Cancer? Dr. Ella L. Kim, Laboratory Director, Johannes Gutenberg University Medical Centre Mainz, Germany |
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14:15-14:35 |
Title: Melanoma: Mohs Micrographic Surgery and New Therapetics Utilized at Mayo Clinic Dr. Elliott Campbell, Dermatologist, Mohs Micrographic Surgery and Dermatologic Oncology, Mayo Clinic, USA |
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14:35-14:55 |
Title: Iron-quercetin Complex-precondition Mesenchymal Stem Cell (MSC)-derived Extracellular Vesicle Exhibit Immunomodulation and Wound Healing Properties Dr. Nathupakorn Dechsupa, Assistant Professor, Chiang Mai University, Thailand |
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14:55-15:15 |
Title: VX-680 Compound Inhibits PC3 Cells Proliferation, Invasion, And Induces Apoptosis Through Caspase 3 Dependent Pathway Dr. Ahmad Al-Azayzih, Associate Professor, University of Sharjah, UAE |
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15:15-15:30 |
Coffee Break |
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15:30-15:50 |
Title: ROR1 Inhibitor (KAN0441571C) Induces Significant Apoptosis in Hematological Malignancies Dr. Ali Moshfegh, Senior Researcher, Karolinska Institute, Sweden |
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15:50-16:10 |
Title: Metastasis to the Penis from a Bladder Carcinoma Invading only the Lamina Propria: Case Report Dr. Marius Stanimir, Urologist, CHU Saint-Pierre, Belgium |
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16:10-16:30 |
Title: Delivery of Cancer Diagnoses by Gastroenterologists: Room to Grow Dr. Abdelwahab Ahmed, Resident Physician, Northwestern Memorial Hospital Department of Internal Medicine, USA |
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16:30-16:50 |
Title: Iron-quercetin Complex-induced Alters the Peripheral Blood Mononuclear Cell Transcriptome Profile Linked to Improved Biological Functioning Dr. Jiraporn Kantapan, Assistant Professor, Chiang Mai University, Thailand |
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16:50-17:10 |
Title: Novel Mechanism of Liver Oncogenesis: A Potential Therapeutic Target for Hepatocellular Carcinoma Dr. Feng Hong, Assistant Professor, The Ohio State University, USA |
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IDDST 05: Precision Medicine, Immunotherapy, Cell Therapy and Gene Therapy Time: 13:30-16:50, May 22, 2024 (Wednesday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Farzin Farzaneh, Chief Scientific Officer, Virocell Biologics Limited; Professor of Molecular Medicine, King’s College London, UK |
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13:30-13:35 |
Chair's Introduction |
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13:35-13:55 |
Title: Sulindac Modulates the Response of Proficient MMR Colorectal Cancer to Anti-PD-L1 Immunotherapy Dr. Yaguang Xi, Professor and Department Head, University of Georgia, USA |
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13:55-14:15 |
Title: Clinical Outcomes of Chimeric Antigen Receptor T-Cells and Bispecific Antibodies in Acute Leukemias Dr. William Hogan, Associate Professor of Medicine, Mayo Clinic, USA |
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14:15-14:35 |
Title: Bone Marrow-derived Microglia May Have a Clinical Value for Treatment of Alzheimer’s Disease Dr. Beka Solomon, Professor, Tel-Aviv University, Israel |
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14:35-14:55 |
Title: Engineering CAR Tregs to Eradicate Solid Tumors Dr. Alexander T. Sougiannis, Physician Scientist, Medical University of South Carolina, USA |
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14:55-15:15 |
Title: Transformational New Applications of Gene Therapy Dr. Farzin Farzaneh, Chief Scientific Officer, Virocell Biologics Limited; Professor of Molecular Medicine, King’s College London, UK |
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15:15-15:30 |
Coffee Break |
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15:30-15:50 |
Title: Human iPSC-derived VSMCs Exhibit Aging and Original Phenotypes: A Novel Humanized Model for Drug Discovery Dr. Hongyu Qiu, Professor, University of Arizona, USA |
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15:50-16:10 |
Title: Is Immunotherapy the Cure for Hepatocellular Carcinoma Patients Defined by Dysregulated Glucose Metabolic Pathways? Dr. Xiaoli Zhang, Associate Professor, The Ohio State University, USA |
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16:10-16:30 |
Title: Immunodynamics of Lung Cancer: From Single-Cell Bioinformatics to AI-guided Drug Discovery Dr. Patrick Ming-Kuen Tang, Assistant Professor, The Chinese University of Hong Kong, Hong Kong, China |
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16:30-16:50 |
Title: Translating BAFF-R CAR-T Treatment to CLL: Bridging Bench to Bedside Dr. Yan Luo, Assistant Professor, Mayo Clinic, USA |
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IDDST 06: Artificial Intelligence in Drug Discovery Time: 08:30-12:10, May 23, 2024 (Thursday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. James J. Cai, Professor, Texas A&M University, USA |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: Data-centric Approaches in Biology and Computational Chemistry Dr. Frederick Abraham, President and CEO, Simulo Inc, USA |
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09:00-09:25 |
Title: Exploring Advanced Frontiers in Single-Cell Bioinformatics: Moving Beyond Differential Expression Analysis Dr. James J. Cai, Professor, Texas A&M University, USA |
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09:25-09:50 |
Title: AI to Predict Drug-drug Interactions and Pharmacogenetics of Drug Metabolizing Enzymes Dr. Maria A. Miteva, Research Director at Inserm, Inserm U1268, UMR 8038 CNRS - University Paris Cité, France |
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09:50-10:15 |
Title: A Multimodal Deep Learning Approach to Prediction of Cognitive Decline and Its Potential Application in Clinical Trial for Alzheimer’s Disease Dr. Yuanzhong Li, Senior Research Manager, Imaging Technology Center, FUJIFILM Corporation, Japan |
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10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: AI Based Integrated Genomics for Genetic Subtyping and Drug Repositioning in Alzheimer’s Disease Dr. Gyungah Jun, Associate Professor, Boston University, USA |
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10:55-11:20 |
Title: Drug Design Using Quantum Mechanics and Machine Learning Dr. Wenjin Zhou, Assistant Professor, Richard A. Miner School of Computer and Information Sciences, Kennedy College of Sciences, University of Massachusetts - Lowell, USA |
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11:20-11:45 |
Title: A Tale of Two Approaches: Physics-based vs. Data-driven Models in Drug Discovery Dr. Niu Huang, Principle Investigator, National Institute of Biological Sciences, China |
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11:45-12:10 |
Title: Integrating Artificial Intelligence/Machine Learning for Revolutionizing Molecular Recognition and Therapeutic Dr. Abdulmohsen H. Alrohaimi, Dean, Shaqra University, Saudi Arabia |
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IDDST 07: Frontiers in Pharmacology and Toxicology, Drug Metabolism and Pharmacokinetics Time: 08:30-11:45, May 23, 2024 (Thursday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. George Udeani, Clinical Professor, Texas A&M University, USA |
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Co-Chair |
Dr. Raphael Serreau, EPSM GEORGES DAUMEZON, CNRS UPR 4301, France |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: USA National Institute of Health Countermeasures Against Chemical Threats Research on Acetylcholinesterase Oximes Reactivators Dr. David Jett, Director, Division of Translational Research, NIH, USA |
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09:00-09:25 |
Title: Mechanistic Static Models for the Prediction of Drug-drug Interactions Dr. Sheila Annie Peters, Executive Director, Boehringer Ingelheim, Germany |
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09:25-09:50 |
Title: Leveraging Pharmacogenomics in Preclinical Pharmacokinetics and Pharmacodynamics Dr. George Udeani, Clinical Professor, Texas A&M University, USA |
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09:50-10:15 |
Title: Integration of In Vitro Transporter Inhibition and Regulation to Improve Prediction of Cholestatic Hepatotoxicity: The C-DILI™ Assay Dr. Kenneth R. Brouwer, Vice President - Technology, ADMETOX, BioIVT, USA |
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10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: Polycystic Ovarian Syndrome and Risk of Cardiovascular Events Dr. Salma Iftikhar, Assistant Professor, Mayo Clinic, USA |
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10:55-11:20 |
Title: Psychedelic: Severe Alcohol Dependency: New Therapeutics Possibilities from Psychedelic Drugs Dr. Raphael Serreau, EPSM GEORGES DAUMEZON, CNRS UPR 4301, France |
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11:20-11:45 |
Title: Oral Clonidine in the Management of Resistant Cancer Pain- A Case Report Ms. Olfat Zekry, Pharmacology Unit Coordinator, University of Sydney, Australia |
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IDDST 08: Glia Cells and Neurological Disorders & CNS Diseases Time: 08:30-11:20, May 23, 2024 (Thursday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Eduard Korkotian, Professor, Department of Neurobiology, The Weizmann Institute of Science, Israel |
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Co-Chair |
Dr. Michele Papa, Professor, University of Campania “Luigi Vanvitelli”, Italy |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: The Effect of Apigenin on the Function of Human α7-Nicotinic Acetylcholine Receptors Dr. KeunHang Susan Yang, Professor, Chapman University, USA |
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09:00-09:25 |
Title: Interaction of Astrocytic and Neuronal Mitochondria in Normal and Neurodegeneration Dr. Eduard Korkotian, Professor, The Weizmann Institute of Science, Israel |
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09:25-09:50 |
Title: Glia-based Maladaptive Plasticity in CNS: Neuron-glia Interplay and Beyond Dr. Michele Papa, Professor, University of Campania “Luigi Vanvitelli”, Italy Dr. Giovanni Cirillo, Assistant Professor, University of Campania “Luigi Vanvitelli”, Italy |
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09:50-10:15 |
Title: Harnessing the Power of Placebo in Clinical Neurology: Conditioning of the Immune Response and the Paradigm of the Dose Extension Model Dr. Aziz Shaibani, Clinical Professor of Medicine, Baylor College of Medicine, USA |
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10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: Pharmacological Treatment of Paraphilic and Compulsive Sexual Behavior Disorders Drs. Richard Krueger & Meg Kaplan, Clinical Professors of Psychiatry and Psychology in Psychiatry, Columbia University Medical Center Department of Psychiatry, USA |
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10:55-11:20 |
Title: Protein Disulfide Isomerase as Therapeutic Target for Heat Hyperalgesia in Chronic Pain Dr. Xiaona Du, Professor, Hebei Medical University, China |
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IDDST 09: Infectious Diseases Time: 13:30-16:20, May 23, 2024 (Thursday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Jonathan Ross, Professor of Sexual Health and HIV, University of Birmingham, UK |
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13:30-13:35 |
Chair's Introduction |
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13:35-14:00 |
Title: Early Drug Development for Anti-Infectives: The Role of Radiolabeled Microtracer Studies for Drug Distribution, Compartmental Quantitation and Metabolism Dr. Bradly D. Keck, Director of Radiopharmaceutics, Pharmaron Clinical Pharmacology Center, USA |
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14:00-14:25 |
Title: Beyond Cephalosporins - What are the Options for Managing N. gonorrhoeae? Dr. Jonathan Ross, Professor of Sexual Health and HIV, University of Birmingham, UK |
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14:25-14:50 |
Title: Candida Infections in Immunocomptomised Patients: An Overview from Kuwait Dr. Eiman Mokaddas, Professor, Kuwait University, Kuwait |
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14:50-15:15 |
Title: Modern Approaches and Techniques for Microbiological Diagnosis of Bloodstream Infections Dr. Michael M. Petrov, Associate Professor, Medical University of Plovdiv, Bulgaria |
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15:15-15:30 |
Coffee Break |
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15:30-15:55 |
Title: A Type VII Secretion System in Virulence and Potential as Biomarkers Dr. Yi Xu, Associate Professor, Texas A&M Health Science Center, USA |
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15:55-16:20 |
Title: The Landscape of Antibiotic-resistance in Breast Infections in Malaysia Dr. Crystale Siew Ying Lim, Associate Professor & Dean, Faculty of Applied Sciences, UCSI University, Malaysia |
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IDDST 10: Inflammation and Immunological Diseases Time: 13:30-17:10, May 23, 2024 (Thursday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Johan Lund, Chief Scientific Officer, Aqilion AB, Sweden |
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13:30-13:35 |
Chair's Introduction |
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13:35-14:00 |
Title: Guillain-Barre Syndrome in Bangladesh: A Translation from Cross-sectional Research to Phase III Clinical Trial Dr. Zhahirul Islam, Senior Scientist and Head, Laboratory of Gut-Brain Axis, International Centre for Diarrhoeal Disease Research, Bangladesh |
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14:00-14:25 |
Title: GPCR19 Agonist Ameliorates Atopic Dermatitis by Suppressing Inflammasome Dr. Seung-Yong Seong, Professor, Seoul National University College of Medicine, South Korea |
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14:25-14:50 |
Title: Development of AQ280 and AQ312 for the Treatment of Inflammatory GI Disorders Dr. Johan Lund, Chief Scientific Officer, Aqilion AB, Sweden |
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14:50-15:15 |
Title: Severe Complications of Acute Appendicitis with the Laparoscopic Approach Dr. Jesus Alberto Bahena Aponte, Professor, Hospital Medica Sur, Mexico |
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15:15-15:30 |
Coffee Break |
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15:30-15:55 |
Title: An Opportunity for the Treatment of Inflammatory Diseases: Fraxinus Species Dr. Burcu Sen, Associate Professor, Istanbul University, Turkey |
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15:55-16:20 |
Title: Multi-omics Approaches to Investigating the Interaction between Obesity and Autoimmune Diseases Dr. Heekyong Rachel Bae, Visiting Faculty, Kyungpook National University, South Korea |
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16:20-16:45 |
Title: Relationship between Multiple Autoimmune Diseases: Rare Cases from Saudi Arabia Dr. Faris Q. Alenzi, Consultant and Professor of Immunology, Prince Sattam bin Abdulaziz University, Saudi Arabia |
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16:45-17:10 |
Title: Purulent Meningitis and Secondary Epilepsy Caused by Mycobacterium Iranicum Infection Dr. Xinyu Zhou, Deputy Chief Physician, Department of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, China Dr. Yong Sun, Professor, Department of Neurosurgery, The Affiliated Lianyungang Hospital of Xuzhou Medical University, China |
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IDDST 11: Cardiovascular & Metabolic Disorders& Other Diseases Time: 13:30-17:10, May 23, 2024 (Thursday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Shu Ye, Professor, National University of Singapore, Singapore |
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Co-chair |
Dr. Wen-Jun Shen, Senior Research Scientist, Stanford University School of Medicine, USA |
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13:30-13:35 |
Chair's Introduction |
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13:35-13:55 |
Title: Liver Transplantation for Portopulmonary Hypertension Dr. James Runo, Professor of Medicine, University of Wisconsin School of Medicine and Public Health, USA |
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13:55-14:15 |
Title: Investigation into Causal Genes and Potential Therapeutic Targets of Coronary Heart Disease Dr. Shu Ye, Professor, National University of Singapore, Singapore |
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14:15-14:35 |
Title: Trends of Innovative Machine Learning and Deep Learning-based Diagnosis and Prediction Systems for the Occurrences of Major Adverse Cardiovascular Events Dr. Jong Yun Lee, Professor, Chungbuk National University, South Korea |
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14:35-14:55 |
Title: Activity-balanced GLP-1/GDF15 Dual Agonist ZT007 Reduces Body Weight and Metabolic Disorder in Mice and Non-human Primates Dr. Yuanyuan Zhang, Co-Founder and Vice President, Beijing QL Biopharmaceutical Co., Ltd., China |
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14:55-15:15 |
Title: The Impact of the Inflammatory Ratios Neutrophil-to-lymphocyte Ratio (NLR), Monocyte-to-lymphocyte Ratio (MLR), Platelet-to-lymphocyte Ratio (PLR) on Abdominal Aortic Aneurysm Growth Dr. Marina Stevanov, Vascular Surgery Resident and Assistant, Graz Medical University, Austria |
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15:15-15:30 |
Coffee Break |
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15:30-15:50 |
Title: Advances in Insulin Therapy Dr. Margo S. Hudson, Assistant Professor, Harvard Medical School, USA |
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15:50-16:10 |
Title: Therapeutic Potential of Nordihydroguaiaretic Acid (NDGA) in the Management of Metabolic Syndrome and Associated Complications Dr. Wen-Jun Shen, Senior Research Scientist, Stanford University School of Medicine, USA |
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16:10-16:30 |
Title: The Role ofIonomycin in the Improvement of in vitro Fertilization and Increasing the Rate of Bovine Embryo Development Dr. Mohammed Aleissa, Professor of Developmental Biology and Embryology, Al-Imam Muhammad Ibn Saud Islamic University, Saudi Arabia |
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16:30-16:50 |
Title: Dental and Genetic Management of Syndromic Patient with Hypodontia and Microdontia: 17 Year-long Follow-up Dr. Isabelle Bailleul-Forestier, Professor, Toulouse University, France |
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16:50-17:10 |
Title: Diagnosis and Surgical Management of Female Urethral Diverticula in Contemporary Era and Its Repercussions on Sexuality Dr. Marcelo Di Gregorio, Associate Head of Clinic, UCL Namur University Hospital, Belgium |
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IDDST 12: Natural Product Discovery Time: 08:30-11:30, May 24, 2024 (Friday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Dulcie A. Mulholland, Professor, University of Surrey, UK |
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08:30-08:35 |
Chair's Introduction |
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08:35-08:55 |
Title: Striking Features and Complex Regulation of Polyketide Antibiotic Auricin from Streptomyces Lavendulae Subsp. Lavendulae CCM 3239 Dr. Jan Kormanec, Head of the Department of Genomics and Biotechnology, Institute of Molecular Biology, Slovak Academy of Sciences, Slovakia |
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08:55-09:15 |
Title: The Potential of Naturally-occurring and Synthetic Homoisoflavonoids for the Treatment of Retinopathy Dr. Dulcie A. Mulholland, Professor, University of Surrey, UK |
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09:15-09:35 |
Title: A Versatile Evaluation on the Potential of Valeriana Species Against Insomnia Dr. Burcu Sen, Associate Professor, Istanbul University, Turkey |
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09:35-09:55 |
Title: Invasiveness Inhibition and Actin Disintegration of Epithelial Cancer Cells by Cucurbitacin B Dr. Cheng-Chen Huang, Professor, University of Wisconsin-River Falls, USA |
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09:55-10:15 |
Title: Drug Discovery of Anticancer with Nitrogen-carrying Constituents, Privileged Derivatives Which Originated from Pentacyclic Triterpenoids Dr. Sithenkosi Mlala, Lecturer, University of Fort Hare, South Africa |
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10:15-10:30 |
Coffee Break |
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10:30-10:50 |
Title: Anthocyanin-accumulated Bioengineered Tomatoes for Colorectal Cancer Prevention in Animal Models Dr. Weiqun Wang, Professor & Director, Kansas State University, USA |
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10:50-11:10 |
Title: Phytochemical Screening and GC-MS Chemical Profiling of an Innovative Anti-cancer Herbal Formula (PHF6) Dr. Mohammed Mousa Al-Zharani, Associate Professor, Imam Mohammad Ibn Saud Islamic University, Saudi Arabia |
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11:10-11:30 |
Title: To Treat Psoriasis, Chinese Herbal Medicine Cannot be Absent Dr. Sheng-Jie Yu, Associate Fellow / Assistant Professor, Taichung Veterans General Hospital / NCHU, Taiwan |
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IDDST 13: Biotherapy & Oncology Research Time: 08:30-11:20, May 24, 2024 (Friday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Qing Chen, Associate Scientific Director, Amgen Inc., USA |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Session Keynote Speech Title: Peptide Nanocarriers Co-delivering an Antisense Oligonucleotide and Photosensitizer Elicit Synergistic Cytotoxicity Dr. Cornelia G. Palivan, Professor, University of Basel, Switzerland |
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09:00-09:25 |
Title: Integral Membrane Proteins as Drug Targets: Challenges and Applications Dr. Qing Chen, Associate Scientific Director, Amgen Inc., USA |
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09:25-09:50 |
Title: Human Heavy Chain Only Transgenic, Source of Single Domain Antibodies Building Blocks for Diagnostic and Therapeutic Application Dr. Dubravka Drabek, Senior Scientist & Principal Investigator, Cell Biology Department Erasmus MC/Harbour Biomed, the Netherlands |
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09:50-10:15 |
Title: Precancerous and Cancerous Lesions of Aral Cavity: Prevention and New Therapeutic Solutions Dr. Paolo Brunamonti Binello, Professor, University of Genoa, Italy |
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10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: Lessons Learned from Donor Cell-derived Myeloid Neoplasms after Allogenic Hematopoietic Cell Transplantation Dr. Katalin Kelemen, Professor, Mayo Clinic, USA |
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10:55-11:20 |
Title: The Influence of the Microbiome on Immunotherapy for Gastroesophageal Cancer Dr. Moses S. Raj, Senior Attending, Allegheny Health Network Cancer Institute, USA |
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IDDST 14: Drug Bioprocessing & Manufacturing and Integrative Services Time: 08:30-10:15, May 24, 2024 (Friday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Mr. Richard Denk, Senior Consultant, SKAN AG, Switzerland |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: QbD in Biopharmaceutical Manufacturing and Biosimilar Development Dr. Christina Vessely, Senior Consultant, Biologics Consulting Group, Inc., USA |
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09:00-09:25 |
Title: Points to Consider for the Commercial Manufacturing of Cell & Gene Therapies Mr. Richard Denk, Senior Consultant, SKAN AG, Switzerland |
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09:25-09:50 |
Title: Pricing and Reimbursement of Regenerative Medicine Products in Japan Ms. Na Wei, Partner, Simon-Kucher & Partners, Japan |
| 09:50-10:15 |
Title: Pertuzumab and Trastuzumab for Early and Metastatic Breast Cancer (Video) Dr. Leonor Abreu Ribeiro, Medical Oncology Consultant, University Hospital of Lisbon, Portugal |
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IDDST 15: Young Scientist' Forum Time: 10:30-11:55, May 24, 2024 (Friday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Mr. Richard Denk, Senior Consultant, SKAN AG, Switzerland |
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10:30-10:35 |
Chair's Introduction |
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10:35-10:55 |
Title: The Decline in Cellular Iron Content is a Crucial Element for the Execution of the Differentiation Program in Cultured Keratinocytes Mr. Junya Abe, Student, Kwansei Gakuin University, Japan |
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10:55-11:15 |
Title: DP-independent E2F Activity as a Target of Cancer Specific Therapeutics Ms. Rinka Nakajima, Graduate Student, Kwansei Gakuin University, Japan |
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11:15-11:35 |
Title: Acute Toxicity and Biodistribution of Iron-quercetin Complex, A New MRI Contrast Agent Ms. Phattarawadee Innuan, Master Student, Chiang Mai University, Thailand |
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11:35-11:55 |
Title: TP53 Status is a Potential Predictive Marker for Efficacy of Glioblastoma Stem Cells Radiosensitisation by Chloroquine Mr. Andreas Muller, PhD Student, Laboratory of Experimental Neurooncology, Clinic for Neurosurgery, Johannes Gutenberg Medical University Mainz, Germany |
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IDDST 16: Video Forum |
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1 |
Title: Artificial Intelligence (AI) and Alternative Variables (AV) in Drug Discovery: A Promising Alliance Dr. Celerino Abad-Zapatero, Research Professor, Institute for Tuberculosis Research, University of Illinois Chicago, USA |
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2 |
Title: Nutrition and Healthy Dr. Rong Liu, Professor, China Agricultural University, China |
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3 |
Title: Modeling of the Composition of Polymer Films, Production, And Quality Assessment Dr. Modestas Zilius, Researcher, Lithuanian University of Health Sciences, Lithuania |
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4 |
Title: New Thinking in Clinical Trials: The Estimand Journey Dr. Christine Fletcher, Vice President Biostatistics, GSK, UK |
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5 |
Title: Biomarkers of Brain Network Function in Drug Development: AI-informed Heuristic and Target Predictions Using EEG Tomography in Nonhuman Primates and Humans Dr. Monica Metea, Founder/Consultant, Preclinical Electrophysiology Consulting, LLC, USA |
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6 |
Title: Reclaiming African Indigenous Medicine and its Associated Value Dr. Mandla S Makhanya, Professor, University of South Africa, South Africa |
The 11th Annual International Symposium of Drug Delivery Systems (SDDS-2024)
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SDDS 01: Novel Drug Delivery Technologies & Advanced Carriers Materials Time: 08:30-12:10, May 23, 2024 (Thursday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Dan Myers, Vice President, Product Research & Development, Alexza Ferrer, USA |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: Targeted Drug Delivery Is the Main Challenge in Nanomedicine Dr. Sandor G. Vari, Director, Cedars-Sinai Medical Center, USA |
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09:00-09:25 |
Title: Liposomal Delivery for Potentiated STING Activation Dr. Chalet Tan, Professor, The University of Tennessee Health Science Center, USA |
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09:25-09:50 |
Title: The Staccato™ System: A Novel Approach for Treatment of Acute Conditions Dr. Dan Myers, Vice President, Product Research & Development, Alexza Ferrer, USA |
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09:50-10:15 |
Title: Transethosome-Encapsulated Bouea macrophylla Seed Extract for Anti-Acne Application: Response Surface Methodology, Antibacterial Efficacy, and Safety Assessment Dr. Worrapan Poomanee, Assistant Professor, Chiang Mai University, Thailand |
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10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: Applications of Calcium Ion-induced Quercetin Nanoemulsion Gel-Forming Eye Drops for Delaying Degeneration of Eye Lens Dr. Rathapon Asasutjarit, Associate Professor, Thammasat University, Thailand |
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10:55-11:20 |
Title: Use of Selective Laser Sintering for 3D Printing of Oral Dosage Forms Dr. Jonas Lindh, Associate Professor, Uppsala University, Sweden |
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11:20-11:45 |
Title: PharmaJet - Leading a Transformation on How Medicines Harness the Full Power of the Immune System Mr. Chris Cappello, President & CEO, PharmaJet Inc., USA |
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11:45-12:10 |
Title: The Effect of Centella Asiatica on Wound Healing and Immune System Dr. Elena Arribas-Lopez, Lecturer/Researcher, University of Greenwich, UK |
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SDDS 02: Targeted Drug Delivery & Drug Formulation Time: 13:30-16:10, May 23, 2024 (Thursday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Miriam Kidron, Chief Scientific Officer and Director, Oramed Pharmaceuticals, Israel |
|
13:30-13:35 |
Chair's Introduction |
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13:35-13:55 |
Title: Inhaled Chemotherapies as Potential New Locoregional Modality to Increase the Immune Therapy Response in Lung Cancer Treatment Dr. Nathalie Wauthoz, Professor, Université Libre de Bruxelles, Belgium |
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13:55-14:15 |
Title: Pathway for Formulation Development from Discovery to Phase I Clinical Formulation Dr. Elizabeth Kwong, Consultant, Kwong Eureka Solutions, Canada |
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14:15-14:35 |
Title: Ad Hoc Analysis to Optimize Eligibility of Patients with Type 2 Diabetes Mellitus for Oral Insulin Treatment Dr. Miriam Kidron, CSO, Oramed Pharmaceuticals, Israel |
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14:35-14:55 |
Title: Interaction Effects Assessment Between Siloxanes and Human Stratum Corneum and Impact on Skin Barrier Dr. Krystyna Mojsiewicz-Pienkowska, Assistant Professor, Medical University of Gdansk, Poland |
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14:55-15:15 |
Title: Advancing Lipid-Based Formulations and Softgels in Drug Development. Dr. Masataka Katsuma, Director, Product Development, Catalent Japan Co., Ltd., Japan |
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15:15-15:30 |
Coffee Break |
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15:30-15:50 |
Title: The Opportunity for Dry Powder Intranasal Drug Delivery: Formulation and Device Considerations Mr. Lucas Silva, Senior Specialist for OINDP Analytical Development, Nanopharm, An Aptar Pharma Company, UK |
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15:50-16:10 |
Title: Targeted Delivery of TGFβ mRNA to Lung Parenchyma Using One-component Ionizable Amphiphilic Janus Dendrimers Dr. Elena Atochina-Vasserman, Research Assistant Professor, University of Pennsylvania, USA |
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SDDS 03: Biotherapeutic Drug Delivery & Drug Delivery Systems for Major Diseases Time: 08:30-11:45, May 24, 2024 (Friday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Yuhua Li, Co-founder and SVP of R&D, Foresee Pharmaceuticals Co., Ltd., USA |
|
08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: Small Molecule-Based Therapies for Enhancing Bone Repair and Regeneration Dr. Wai Hong (Kevin) Lo, Associate Professor, University of Connecticut Health Center, USA |
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09:00-09:25 |
Title: Stable Injectable Formulation for Sustained Release Delivery of Leuprolide for the Treatment of Advanced Prostate Cancer Dr. Yuhua Li, Co-founder and SVP of R&D, Foresee Pharmaceuticals Co., Ltd., USA |
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09:25-09:50 |
Title: Use of Nucleoside-modified mRNA Encoding Regenerative Factors Encapsulated in Lipid Nanoparticles to Alleviate Acute and Chronic Murine Liver Diseases Dr. Valerie Gouon-Evans, Associate Professor, Boston University School of Medicine, Boston Medical Center, USA |
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09:50-10:15 |
Title: Glymphatic System in Drug Delivery Dr. Quan Jiang, Senior Scientist and Professor, Henry Ford Health & Michigan State University, USA |
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10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: Development of Novel Phosphodiesterase 5 Inhibitors for the Therapy of Alzheimer's Disease Dr. Ottavio Arancio, Professor, Columbia University, USA |
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10:55-11:20 |
Title: Enhancing PRIMA-1-mediated Restoration of Mutant p53 in Prostate Cancer Cells via CD24 Suppression Dr. Runa Liu, Professor, University of Alabama, Birmingham, USA |
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11:20-11:45 |
Title: Targeted Reactivation of X-linked Endogenous Genes in Human Female Breast Cancer Cells Dr. Lizhong Wang, Professor, UAB School of Medicine, USA |
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SDDS 04: Video Forum |
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1 |
Title: Flexible IL-27 Based Immunotherapy Approaches for Bone Metastases Dr. Marxa L. Figueiredo, Associate Professor, Basic Medical Sciences, Purdue University, USA |
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2 |
Title: Application of Freeze Drying Technology in the Production of Fast Melt Films containing Quetiapine Fumarate Dr. Liew Kai Bin, Associate Professor, University of Cyberjaya, Malaysia |
The 2nd World Chemistry Congress 2024 (IWCC-2024)
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IWCC 01: Biochemistry, Organic and Medicinal Chemistry Time: 08:30-12:10, May 23, 2024 (Thursday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Abul K Fazlur Rahman, Professor and Chair, The University of Oklahoma, USA |
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Co-Chair |
Dr. Joanna Dulinska-Litewka, Chair, Jagiellonian University Medical College, Poland |
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08:30-08:35 |
Chair's Introduction |
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08:35-09:00 |
Title: The Intriguing Story of Carbocation and its Hyper-Valency Dr. Abul K Fazlur Rahman, Professor and Chair, The University of Oklahoma, USA |
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09:00-09:25 |
Title: AI-Enhanced Capabilities in Research from Target to Drug Discovery: Challenges and Opportunities. Dr. Jean Philippe Stephan, Senior Director, Institut de Recherches SERVIER, France |
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09:25-09:50 |
Title: Unique Nitric Oxide Synthesis Activities from Bacterial Nitric Oxide Synthases |
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09:50-10:15 |
Title: Modified Nanoparticles for Cancer Therapy |
|
10:15-10:30 |
Coffee Break |
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10:30-10:55 |
Title: Affinity-Directed Site-Specific Protein Labeling and Its Application to Antibody-Drug Conjugates |
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10:55-11:20 |
Title: Structure-Cytotoxicity Relationship Study of Renieramycins Against Non-Small Cell Lung Cancer Cell Lines |
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11:20-11:45 |
Title: Advancements in Non-spherical Nanoparticle Synthesis through Initiated Chemical Vapor Deposition Dr. Di Zhang, Postdoctoral Associate, Cornell University, USA |
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11:45-12:10 |
Title: A FRET-Based Respirasome Assembly Screen Identifies Spleen Tyrosine Kinase as A Target to Improve Muscle Mitochondrial Respiration and Exercise Performance in Mice |
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IWCC 02: Analytical, Inorganic & Physical Chemistry Time: 13:30-17:50, May 23, 2024 (Thursday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Lili Zhang, Senior Scientist & Division Director, A*STAR, Singapore |
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Co-Chair |
Dr. Waleed Saeed, Lead Geologist, Saudi Arabian Oil Company, Saudi Arabia. |
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13:30-13:35 |
Chair's Introduction |
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13:35-13:55 |
Session Keynote Speech Title: Design, Optimization, and Construction of High-Performance Potassium-Ion Battery Electrodes Dr. Hsing-Yu Tuan, Professor, NTHU, Taiwan |
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13:55-14:15 |
Title: Engineering Multifunctional Inorganic Materials for Sustainable Catalysis |
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14:15-14:35 |
Title: Surface Modifications and Coatings in Chromatography Dr. Kazuo Watanabe, SilcoTek Corporation, Japan |
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14:35-14:55 |
Title: Systematic Evaluation of the Application of Wireless Devices for Water Analysis in a Campus Storm Water Management Program Dr. Wai Man (Karno) Ng, Associate Professor, California State University San Marcos, USA |
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14:55-15:15 |
Title: Hydroformylation: a Synergy of Academic and Industrial Chemistry Dr. Baoxin Zhang, Research Scientist, Leibniz Institute for Catalysis, Germany |
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15:15-15:30 |
Coffee Break |
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15:30-15:55 |
Title: Laboratory Experiments to Evaluate the Effectiveness of Persulfate to Oxidize BTEX in Saline Environment and at Elevated Temperature Using Stable Isotopes Dr. Waleed Saeed, Lead Geologist, Saudi Arabian Oil Company, Saudi Arabia |
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15:55-16:20 |
Title: The Development of Chemical Methods for Quality Control of Ziziphi Spinosae Semen |
|
16:20-16:45 |
Title: Using Artificial Intelligence (AI) to Combine Visible Near Infrared (Vis-NIR) Spectroscopy with Lab-Based Techniques for Predicting Nitrogen Levels in Leaves to Enhance Fertilizer Application in Bananas |
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16:45-17:10 |
Title: Monolithic Materials in Glycoprotein Analysis Dr. Allan Jonson Alla, Senior Lecturer, University of Technology and Applied Sciences (UTAS) - Muscat, Oman |
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17:10-17:30 |
Title: Competitive or Sequential Reaction of an Electrophilic Terminal Phosphinidene Metal(0) Complex with Allyl Halides? [2+1]-Cycloaddition vs C-X Bond Insertion Dr. Arif Ali Khan, Assistant Professor, Guru Gobind Singh Indraprastha University, India |
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17:30-17:50 |
Title: Advanced Thermal Management Materials for Electronic Packaging |
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IWCC 03: Industrial and Green Chemistry Time: 08:30-12:20, May 24, 2024 (Friday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay |
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Chair |
Dr. Harold Boone, Research Director, The Dow Chemical, USA |
|
Co-Chair |
Dr. Nouf Al Jabri, King Abdullah University of Science and Technology, Saudi Arabia |
|
08:30-08:35 |
Chair's Introduction |
|
08:35-08:55 |
Title: Liquid Phase Nanostructuring and 2D Patterning of Metal Oxide Thin Films - TiO2, ZnO, Fe3O4, Ta2O5, SnO2 - |
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08:55-09:15 |
Title: Decarbonize and Grow Challenges in Achieving Carbon Neutrality By 2050 |
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09:15-09:35 |
Title: BioSensors for Sustainable Agriculture & the Environment |
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09:35-09:55 |
Title: Innovative biomass based sustainable aviation fuel production process – A techno-economic and sustainability assessment Dr. Ralph-Uwe Dietrich, R&D Manager, German Aerospace Center, Germany |
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09:55-10:15 |
Title: Lignin Vlarization Through Its Chemical Modification. Dr. Byung-Dae Park, Professor, Kyungpook National University, South Korea |
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10:15-10:30 |
Coffee Break |
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10:30-10:50 |
Title: Electrocatalysis Using Main-Group-Element-based Molecular Catalysts |
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10:50-11:20 |
Title: The Discovery of Bioactive Antioxidants in Wheat Brans for Retarding Skin- and Health-ageing |
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11:20-11:40 |
Title: Tracers’ Development Journey to Iluminate Reservoirs: Case Studies and Futuristic Directions |
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11:40-12:00 |
Title: Preliminary Topic of His Speech – Palladium Containing Catalysts in Chemical Synthesis Technologies Dr. Dmitry Korolev, Lead manager, MMC Norilsk Nickel., Russia |
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12:00-12:20 |
Title: The Research of Assumption Principles of Deposition Potentials of Uranium and Uranium Alloys Formed with Fe/Co/Ni In Licl-Kcl At 773 K |
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IWCC 04: Video Forum |
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Title: Breakthrough Zero-CO2 Distributed Power Source Dr. Randell Mills, Brilliant Light Power, Inc., USA |
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Posters & Papers |
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IDDST 01 |
Title: Antimicrobial Resistance among Bloodstream Pathogens, Antibiotic Consumption, and the Financial Burden and Impact on the Biggest Hospital in Bulgaria Dr. Gergana Lengerova, Assistant Professor, Medical University of Plovdiv, Bulgaria |
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IDDST 02 |
Title: Biologically Synthesized Silver Nanoparticles as Potent Antibacterial Effective Against Multidrug-resistant Pseudomonas Aeruginosa Dr. Ana Maria Fernandez-Presas, Principal Investigator, National Autonomous University of Mexico, Mexico |
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IDDST 03 |
Title: Antimicrobial and Anti-inflammatory Activity of Cystatin C on Human Gingival Fibroblast Incubated with Porphyromonas Gingivalis Dr. Ana Maria Fernandez-Presas, Principal Investigator, National Autonomous University of Mexico, Mexico |
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