IDDST-2024
Scientific Program

 

Program

Time: May 22-24, 2024

Venue: Grand Prince Hotel Osaka Bay, Osaka, Japan

 

Registration

Time: 09:00-21:00, May 21, 2024 (Tuesday); Place: Lobby, 1F, Grand Prince Hotel Osaka Bay

 

Opening Ceremony

Time: 09:00-09:10, May 22, 2024 (Wednesday); Place: Crystal & Ruby, 2F, Grand Prince Hotel Osaka Bay

 

Keynote Forum

Time: 09:10-11:45, May 22, 2024 (Wednesday); Place: Crystal & Ruby, 2F, Grand Prince Hotel Osaka Bay

Moderator

Dr. Matthias von Herrath, Scientific Director of the Diabetes Research Institute, University of Miami School of Medicine; Vice President, Novo Nordisk, USA

09:10-09:15

Moderator's Introduction

 09:15-09:40

Title: TBD

Dr. Muneto Mogi, Global Head, Global Discovery Chemistry, Novartis Institutes for BioMedical Research (NIBR), USA

09:40-10:05

Title: Innovative Chemistry for Pharmaceutical Development

Dr. Jeff Song, Vice President, Boehringer Ingelheim Pharmaceuticals, Inc, USA

10:05-10:30

Title: Pathology of T1D and New Treatment Options

Dr. Matthias von Herrath, Vice President and Senior Medical Officer, Novo Nordisk, USA

10:30-10:55

Title: Continuous Manufacturing of Complex Parenterals such as mRNA Vaccines and Liposomes

Dr. Diane J. Burgess, Distinguished Professor and Pfizer Distinguished Chair of Pharmaceutical Technology, University of Connecticut, USA

10:55-11:20

Title: Pharmacological Profile of Deucrictibant, A Small-molecule Bradykinin B2 Receptor Antagonist in Clinical Development for Hereditary Angioedema

Dr. Anne S.J. Lesage, Chief Early Development Officer, Pharvaris GmbH, Switzerland

11:20-11:45

Title: Eisai’s Quantitative Systems Pharmacology (QSP) Alzheimer’s Disease (AD) Platform: A Tool for Gaining Mechanistic Insight and Generating Testable Hypotheses

Dr. Antonio Cabal, Sr. Director, Biology Based Modeling & Simulation, Eisai Inc., USA

 

The 20th Annual Congress of International Drug Discovery Science & Technology (IDDST-2024)

 

IDDST 01: Novel Analytical & Breakthrough Technology in Drug Discovery

Time: 13:30-16:20, May 22, 2024 (Wednesday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Kiyoshi Nokihara, Founder and CEO/CSO, HiPep Laboratories, Japan

13:30-13:35

Chair's Introduction

13:35-14:00

Session Keynote Speech

Title: Motile and Deformable RNA Nanoparticles Enable both Spontaneous Tumor Targeting with Undetectable Toxicity

Dr. Peixuan Guo, Endowed Chair and Director, The Ohio State University, USA

14:00-14:25

Title: High-Throughput Sequence Determination of On-Bead Cyclic Peptide Libraries for Discovery of Medicinal Molecules

Dr. Kiyoshi Nokihara, Founder and CEO/CSO, HiPep Laboratories, Japan

14:25-14:50

Title: Illuminating Drug Discovery with Bioluminescent Assays  

Dr. Frank Fan, Head of Biology, Promega Corporation, USA 

14:50-15:15

Title: Selective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models

Dr. Guang Zhu, Professor, Hong Kong University of Science and Technology, Hong Kong, China

15:15-15:30

Coffee Break

15:30-15:55

Title: Photodynamic Antimicrobial Function of Carbon Dots

Dr. Liju Yang, Professor, North Carolina Central University, USA

15:55-16:20

Title: Biosensors Integrated in Biological Models for Drug Discovery and Early Diagnosis

Dr. Monica Mir, Senior Researcher, Institute for Bioengineering of Catalonia, Spain

IDDST 02: Breaking Preclinical Research

Time: 13:30-16:45, May 22, 2024 (Wednesday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. John Renger, Chief Scientific Officer, Cerevel Therapeutics, USA

13:30-13:35

Chair's Introduction

13:35-14:00

Title: Pre-clinical Development of a CD8 Selective T Cell Engager for Autoimmune Disease and Cacer

Dr. Xiaoqiang Yan, Founder, Chairman & CEO, ITabMed Ltd., China

14:00-14:25

Title: A Novel Humanized Anti-Secreted Glycoprotein YKL-40 Antibody: Potential for Cancer Therapy

Dr. Rong Shao, Professor, Department of Pharmacology, Shanghai Jiao Tong University School of Medicine, China

14:25-14:50

Title: Identification of TMEM175 Small Molecule Activators as Candidate Disease-Modification Therapeutics for Parkinson Disease

Dr. John Renger, Chief Scientific Officer, Cerevel Therapeutics, USA

14:50-15:15

Title: Uncovering New Avenues to Triumph Over Chemoresistance in Solid Tumors

Dr. Xiaonan Zhang, Associate Professor, Uppsala University, Sweden

15:15-15:30

Coffee Break

15:30-15:55

Title: Onco-target SET/Taf1β Precisely Fine-tunes Chromosome Segregation in the Inner Centromere

Dr. Yuichiro Asai, Assistant Manager, KONICA MINOLTA, INC., Japan

15:55-16:20

Title: Allosteric Ubiquitin E3-ligase Inhibitor for the Treatment of PAH, Autism and Other Diseases

Dr. Gali Prag, Professor, Tel Aviv University, Israel

16:20-16:45

Title: Targeting Human MrgprX1 for the Treatment of Neuropathic Pain

Dr. Takashi Tsukamoto, Professor of Neurology, Johns Hopkins School of Medicine, USA

IDDST 03: Clinical Trials, Pharmacovigilance, Drug Safety and Risk Management

Time: 13:30-16:45, May 22, 2024 (Wednesday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Lin Zhang, Professor of Neurology, UCDavis School of Medicine, USA

13:30-13:35

Chair's Introduction

13:35-14:00

Title: A Novel Compound Chimeric Antigen Receptor for Treatment of Autoimmune Diseases

Dr. Nabil Hagag, Director of Cellular Therapies, Stony Brook Medicine, USA

14:00-14:25

Title: Early Diagnosis of Neurodegenerative Disorders with Biomarkers

Dr. Lin Zhang, Professor of Neurology, UCDavis School of Medicine, USA

14:25-14:50

Title: Radiation-Enhancement of Breast Tumours Through Ultrasound Stimulated Microbubble Treatment - Phase 1 Clinical Trial Results

Dr. Gregory J. Czarnota, Professor, University of Toronto, Canada

14:50-15:15

Title: Established Safety of Human Serum Albumin in Aesthetic Botulinum Toxin Formulations

Dr. Andrew Curry, Associate Global Medical Director, Global Medical Affairs, Merz Aesthetics, USA

15:15-15:30

Coffee Break

15:30-15:55

Title: Effects of Rosa Canina L Subspecies (Lito) on Joint Pain, Daily Activities and the Consumption of Rescue Medication in Osteoarthritis with Some References to Weight Loss

Dr. Kaj Winther, Professor, University of Copenhagen, Denmark 

15:55-16:20

Title: Medication Review 2.0, A New Approach to Reduce Medication-related Harm in a Clinical Setting

Dr. Michiel A. van Agtmael, Professor, VU University Medical Center, the Netherlands

16:20-16:45

Title: Ensuring Perioperative and PACU Drug Safety

Dr. Amballur David John, Assistant Professor of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, USA

IDDST 04: Cancers/Tumors

Time: 13:30-17:10, May 22, 2024 (Wednesday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Ella L. Kim, Laboratory Director, Johannes Gutenberg University Medical Centre Mainz, Germany

13:30-13:35

Chair's Introduction

13:35-13:55

Title: Unlocking the Epigenetic Code in Cancer for Novel Therapeutics

Dr. Yali Dou, Professor of Medicine, Marion and Harry Keiper Chair in Cancer Research, University of Southern California, USA

13:55-14:15

Title: Homologous and Heterologous Fusion of Cancer Stem Cells: A Potential Hallmark of Cancer?

Dr. Ella L. Kim, Laboratory Director, Johannes Gutenberg University Medical Centre Mainz, Germany

14:15-14:35

Title: Melanoma: Mohs Micrographic Surgery and New Therapetics Utilized at Mayo Clinic

Dr. Elliott Campbell, Dermatologist, Mohs Micrographic Surgery and Dermatologic Oncology, Mayo Clinic, USA

14:35-14:55

Title: Iron-quercetin Complex-precondition Mesenchymal Stem Cell (MSC)-derived Extracellular Vesicle Exhibit Immunomodulation and Wound Healing Properties

Dr. Nathupakorn Dechsupa, Assistant Professor, Chiang Mai University, Thailand

14:55-15:15

Title: VX-680 Compound Inhibits PC3 Cells Proliferation, Invasion, And Induces Apoptosis Through Caspase 3 Dependent Pathway

Dr. Ahmad Al-Azayzih, Associate Professor, University of Sharjah, UAE

15:15-15:30

Coffee Break

15:30-15:50

Title: ROR1 Inhibitor (KAN0441571C) Induces Significant Apoptosis in Hematological Malignancies

Dr. Ali Moshfegh, Senior Researcher, Karolinska Institute, Sweden

15:50-16:10

Title: Metastasis to the Penis from a Bladder Carcinoma Invading only the Lamina Propria: Case Report

Dr. Marius Stanimir, Urologist, CHU Saint-Pierre, Belgium

16:10-16:30

Title: Delivery of Cancer Diagnoses by Gastroenterologists: Room to Grow

Dr. Abdelwahab Ahmed, Resident Physician, Northwestern Memorial Hospital Department of Internal Medicine, USA

16:30-16:50

Title: Iron-quercetin Complex-induced Alters the Peripheral Blood Mononuclear Cell Transcriptome Profile Linked to Improved Biological Functioning

Dr. Jiraporn Kantapan, Assistant Professor, Chiang Mai University, Thailand

16:50-17:10

Title: Novel Mechanism of Liver Oncogenesis: A Potential Therapeutic Target for Hepatocellular Carcinoma

Dr. Feng Hong, Assistant Professor, The Ohio State University, USA

IDDST 05: Precision Medicine & Recent Development in Immunotherapy, Cell Therapy and Gene Therapy

Time: 13:30-16:50, May 22, 2024 (Wednesday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay

 Chair

Dr. Farzin Farzaneh, Chief Scientific Officer, Virocell Biologics Limited; Professor of Molecular Medicine, King’s College London, UK

13:30-13:35

Chair's Introduction

13:35-13:55

Title: Sulindac Modulates the Response of Proficient MMR Colorectal Cancer to Anti-PD-L1 Immunotherapy

Dr. Yaguang Xi, Professor and Department Head, University of Georgia, USA

13:55-14:15

Title: Clinical Outcomes of Chimeric Antigen Receptor T-Cells and Bispecific Antibodies in Acute Leukemias

Dr. William Hogan, Associate Professor of Medicine, Mayo Clinic, USA

14:15-14:35

Title: Bone Marrow-derived Microglia May Have a Clinical Value for Treatment of Alzheimer’s Disease

Dr. Beka Solomon, Professor, Tel-Aviv University, Israel

14:35-14:55

Title: Engineering CAR Tregs to Eradicate Solid Tumors

Dr. Alexander T. Sougiannis, Physician Scientist, Medical University of South Carolina, USA

14:55-15:15

Title: Transformational New Applications of Gene Therapy

Dr. Farzin Farzaneh, Chief Scientific Officer, Virocell Biologics Limited; Professor of Molecular Medicine, King’s College London, UK

15:15-15:30

Coffee Break

15:30-15:50

Title: Human iPSC-derived VSMCs Exhibit Aging and Original Phenotypes: A Novel Humanized Model for Drug Discovery

Dr. Hongyu Qiu, Professor, University of Arizona, USA

15:50-16:10

Title: Is Immunotherapy the Cure for Hepatocellular Carcinoma Patients Defined by Dysregulated Glucose Metabolic Pathways?

Dr. Xiaoli Zhang, Associate Professor, The Ohio State University, USA

16:10-16:30

Title: Immunodynamics of Lung Cancer: From Single-Cell Bioinformatics to AI-guided Drug Discovery

Dr. Patrick Ming-Kuen Tang, Assistant Professor, The Chinese University of Hong Kong, Hong Kong, China

16:30-16:50

Title: Translating BAFF-R CAR-T Treatment to CLL: Bridging Bench to Bedside

Dr. Yan Luo, Assistant Professor, Mayo Clinic, USA

IDDST 06: Artificial Intelligence in Drug Discovery

Time: 08:30-12:10, May 23, 2024 (Thursday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. James J. Cai, Professor, Texas A&M University, USA

08:30-08:35

Chair's Introduction

08:35-09:00

Title: Data-centric Approaches in Biology and Computational Chemistry

Dr. Frederick Abraham, President and CEO, Simulo Inc, USA

09:00-09:25

Title: Exploring Advanced Frontiers in Single-Cell Bioinformatics: Moving Beyond Differential Expression Analysis

Dr. James J. Cai, Professor, Texas A&M University, USA

09:25-09:50

Title: AI to Predict Drug-drug Interactions and Pharmacogenetics of Drug Metabolizing Enzymes

Dr. Maria A. Miteva, Research Director at Inserm, Inserm U1268, UMR 8038 CNRS - University Paris Cité, France

09:50-10:15

Title: A Multimodal Deep Learning Approach to Prediction of Cognitive Decline and Its Potential Application in Clinical Trial for Alzheimer’s Disease

Dr. Yuanzhong Li, Senior Research Manager, Imaging Technology Center, FUJIFILM Corporation, Japan

10:15-10:30

Coffee Break

10:30-10:55

Title: AI Based Integrated Genomics for Genetic Subtyping and Drug Repositioning in Alzheimer’s Disease

Dr. Gyungah Jun, Associate Professor, Boston University, USA

10:55-11:20

Title: Drug Design Using Quantum Mechanics and Machine Learning

Dr. Wenjin Zhou, Assistant Professor, Richard A. Miner School of Computer and Information Sciences, Kennedy College of Sciences, University of Massachusetts - Lowell, USA

11:20-11:45

Title: A Tale of Two Approaches: Physics-based vs. Data-driven Models in Drug Discovery

Dr. Niu Huang, Principle Investigator, National Institute of Biological Sciences, China 

11:45-12:10

Title: Integrating Artificial Intelligence/Machine Learning for Revolutionizing Molecular Recognition and Therapeutic

Dr. Abdulmohsen H. Alrohaimi, Dean, Shaqra University, Saudi Arabia

IDDST 07: Frontiers in Pharmacology and Toxicology, Drug Metabolism and Pharmacokinetics

Time: 08:30-11:45, May 23, 2024 (Thursday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. George Udeani, Clinical Professor, Texas A&M University, USA

Co-Chair

Dr. Raphael Serreau, EPSM GEORGES DAUMEZON, CNRS UPR 4301, France

08:30-08:35

Chair's Introduction

08:35-09:00

Title: USA National Institute of Health Countermeasures Against Chemical Threats Research on Acetylcholinesterase Oximes Reactivators

Dr. David Jett, Director, Division of Translational Research, NIH, USA

09:00-09:25

Title: Mechanistic Static Models for the Prediction of Drug-drug Interactions

Dr. Sheila Annie Peters, Executive Director, Boehringer Ingelheim, Germany

09:25-09:50

Title: Leveraging Pharmacogenomics in Preclinical Pharmacokinetics and Pharmacodynamics

Dr. George Udeani, Clinical Professor, Texas A&M University, USA

09:50-10:15

Title: Integration of In Vitro Transporter Inhibition and Regulation to Improve Prediction of Cholestatic Hepatotoxicity:  The C-DILI™ Assay

Dr. Kenneth R. Brouwer, Vice President - Technology, ADMETOX, BioIVT, USA

10:15-10:30

Coffee Break

10:30-10:55

Title: Polycystic Ovarian Syndrome and Risk of Cardiovascular Events

Dr. Salma Iftikhar, Assistant Professor, Mayo Clinic, USA

10:55-11:20

Title: Psychedelic: Severe Alcohol Dependency: New Therapeutics Possibilities from Psychedelic Drugs

Dr. Raphael Serreau, EPSM GEORGES DAUMEZON, CNRS UPR 4301, France

11:20-11:45

Title: Oral Clonidine in the Management of Resistant Cancer Pain- A Case Report

Ms. Olfat Zekry, Pharmacology Unit Coordinator, University of Sydney, Australia

IDDST 08: Glia Cells and Neurological Disorders & CNS Diseases

Time: 08:30-11:20, May 23, 2024 (Thursday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Eduard Korkotian, Professor, Department of Neurobiology, The Weizmann Institute of Science, Israel

Co-Chair

Dr. Michele Papa, Professor, University of Campania “Luigi Vanvitelli”, Italy

08:30-08:35

Chair's Introduction

08:35-09:00

Title: The Effect of Apigenin on the Function of Human α7-Nicotinic Acetylcholine Receptors

Dr. KeunHang Susan Yang, Professor, Chapman University, USA

09:00-09:25

Title: Interaction of Astrocytic and Neuronal Mitochondria in Normal and Neurodegeneration

Dr. Eduard Korkotian, Professor, The Weizmann Institute of Science, Israel

09:25-09:50

Title: Glia-based Maladaptive Plasticity in CNS: Neuron-glia Interplay and Beyond

Dr. Michele Papa, Professor, University of Campania “Luigi Vanvitelli”, Italy

Dr. Giovanni Cirillo, Assistant Professor, University of Campania “Luigi Vanvitelli”, Italy

09:50-10:15

Title: Harnessing the Power of Placebo in Clinical Neurology: Conditioning of the Immune Response and the Paradigm of the Dose Extension Model

Dr. Aziz Shaibani, Clinical Professor of Medicine, Baylor College of Medicine, USA

10:15-10:30

Coffee Break

10:30-10:55

Title: Pharmacological Treatment of Paraphilic and Compulsive Sexual Behavior Disorders

Drs. Richard Krueger & Meg Kaplan, Clinical Professors of Psychiatry and Psychology in Psychiatry, Columbia University Medical Center Department of Psychiatry, USA

10:55-11:20

Title: Protein Disulfide Isomerase as Therapeutic Target for Heat Hyperalgesia in Chronic Pain

Dr. Xiaona Du, Professor, Hebei Medical University, China

IDDST 09: Infectious Diseases

Time: 13:30-16:20, May 23, 2024 (Thursday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay

 Chair

Dr. Jonathan Ross, Professor of Sexual Health and HIV, University of Birmingham, UK

13:30-13:35

Chair's Introduction

13:35-14:00

Title: Early Drug Development for Anti-Infectives:  The Role of Radiolabeled Microtracer Studies for Drug Distribution, Compartmental Quantitation and Metabolism

Dr. Bradly D. Keck, Director of Radiopharmaceutics, Pharmaron Clinical Pharmacology Center, USA

14:00-14:25

Title: Beyond Cephalosporins - What are the Options for Managing N. gonorrhoeae?

Dr. Jonathan Ross, Professor of Sexual Health and HIV, University of Birmingham, UK

14:25-14:50

Title: Candida Infections in Immunocomptomised Patients: An Overview from Kuwait

Dr. Eiman Mokaddas, Professor, Kuwait University, Kuwait

14:50-15:15

Title: Modern Approaches and Techniques for Microbiological Diagnosis of Bloodstream Infections

Dr. Michael M. Petrov, Associate Professor, Medical University of Plovdiv, Bulgaria

15:15-15:30

Coffee Break

15:30-15:55

Title: A Type VII Secretion System in Virulence and Potential as Biomarkers

Dr. Yi Xu, Associate Professor, Texas A&M Health Science Center, USA

15:55-16:20

Title: TBD

Dr. Crystale Siew Ying Lim, Associate Professor & Dean, Faculty of Applied Sciences, UCSI University, Malaysia

IDDST 10: Inflammation and Immunological Diseases

Time: 13:30-17:10, May 23, 2024 (Thursday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Johan Lund, Chief Scientific Officer, Aqilion AB, Sweden

13:30-13:35

Chair's Introduction

13:35-14:00

Title: Guillain-Barre Syndrome in Bangladesh: A Translation from Cross-sectional Research to Phase III Clinical Trial

Dr. Zhahirul Islam, Senior Scientist and Head, Laboratory of Gut-Brain Axis, International Centre for Diarrhoeal Disease Research, Bangladesh

14:00-14:25

Title: GPCR19 Agonist Ameliorates Atopic Dermatitis by Suppressing Inflammasome

Dr. Seung-Yong Seong, Professor, Seoul National University College of Medicine, South Korea

14:25-14:50

Title: Development of AQ280 and AQ312 for the Treatment of Inflammatory GI Disorders

Dr. Johan Lund, Chief Scientific Officer, Aqilion AB, Sweden

14:50-15:15

Title: Severe Complications of Acute Appendicitis with the Laparoscopic Approach

Dr. Jesus Alberto Bahena Aponte, Professor, Hospital Medica Sur, Mexico

15:15-15:30

Coffee Break

15:30-15:55

Title: An Opportunity for the Treatment of Inflammatory Diseases: Fraxinus Species

Dr. Burcu Sen, Associate Professor, Istanbul University, Turkey

15:55-16:20

Title: Multi-omics Approaches to Investigating the Interaction between Obesity and Autoimmune Diseases

Dr. Heekyong Rachel Bae, Visiting Faculty, Kyungpook National University, South Korea

16:20-16:45

Title: Regulation of NLRP3 Can be a Potential Therapeutic Approach for Psoriasis Treatment

Dr. Chia-Ling Li, Postdoctoral Fellow, Taichung Veterans General Hospital, Taiwan

16:45-17:10

Title: Relationship between Multiple Autoimmune Diseases: Rare Cases from Saudi Arabia

Dr. Faris Q. Alenzi, Consultant and Professor of Immunology, Prince Sattam bin Abdulaziz University, Saudi Arabia

IDDST 11: Cardiovascular & Metabolic Disorders& Other Diseases

Time: 13:30-17:10, May 23, 2024 (Thursday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Shu Ye, Professor, National University of Singapore, Singapore

Co-chair

Dr. Wen-Jun Shen, Senior Research Scientist, Stanford University School of Medicine, USA

13:30-13:35

Chair's Introduction

13:35-13:55

Title: Liver Transplantation for Portopulmonary Hypertension

Dr. James Runo, Professor of Medicine, University of Wisconsin School of Medicine and Public Health, USA

13:55-14:15

Title: Investigation into Causal Genes and Potential Therapeutic Targets of Coronary Heart Disease

Dr. Shu Ye, Professor, National University of Singapore, Singapore

14:15-14:35

Title: Trends of Innovative Machine Learning and Deep Learning-based Diagnosis and Prediction Systems for the Occurrences of Major Adverse Cardiovascular Events

Dr. Jong Yun Lee, Professor, Chungbuk National University, South Korea

14:35-14:55

Title: Activity-balanced GLP-1/GDF15 Dual Agonist ZT007 Reduces Body Weight and Metabolic Disorder in Mice and Non-human Primates

Dr. Yuanyuan Zhang, Co-Founder and Vice President, Beijing QL Biopharmaceutical Co., Ltd., China

14:55-15:15

Title: The Impact of the Inflammatory Ratios Neutrophil-to-lymphocyte Ratio (NLR), Monocyte-to-lymphocyte Ratio (MLR), Platelet-to-lymphocyte Ratio (PLR) on Abdominal Aortic Aneurysm Growth

Dr. Marina Stevanov, Vascular Surgery Resident and Assistant, Graz Medical University, Austria

15:15-15:30

Coffee Break

15:30-15:50

Title: Advances in Insulin Therapy

Dr. Margo S. Hudson, Assistant Professor, Harvard Medical School, USA

15:50-16:10

Title: Therapeutic Potential of Nordihydroguaiaretic Acid (NDGA) in the  Management of Metabolic Syndrome and Associated Complications

Dr. Wen-Jun Shen, Senior Research Scientist, Stanford University School of Medicine, USA

16:10-16:30

Title: The Role ofIonomycin in the Improvement of in vitro Fertilization and Increasing the Rate of Bovine Embryo Development

Dr. Mohammed Aleissa, Professor of Developmental Biology and Embryology, Al-Imam Muhammad Ibn Saud Islamic University, Saudi Arabia

16:30-16:50

Title: Dental and Genetic Management of Syndromic Patient with Hypodontia and Microdontia: 17 Year-long Follow-up

Dr. Isabelle Bailleul-Forestier, Professor, Toulouse University, France

16:50-17:10

Title: Diagnosis and Surgical Management of Female Urethral Diverticula in Contemporary Era and Its Repercussions on Sexuality

Dr. Marcelo Di Gregorio, Associate Head of Clinic, UCL Namur University Hospital, Belgium

IDDST 12: Natural Product Discovery

Time: 08:30-11:50, May 24, 2024 (Friday); Place: Yamato-A, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Dulcie A. Mulholland, Professor, University of Surrey, UK

08:30-08:35

Chair's Introduction

08:35-08:55

Title: Striking Features and Complex Regulation of Polyketide Antibiotic Auricin from Streptomyces Lavendulae Subsp. Lavendulae CCM 3239

Dr. Jan Kormanec, Head of the Department of Genomics and Biotechnology, Institute of Molecular Biology, Slovak Academy of Sciences, Slovakia

08:55-09:15

Title: The Potential of Naturally-occurring and Synthetic Homoisoflavonoids for the Treatment of Retinopathy

Dr. Dulcie A. Mulholland, Professor, University of Surrey, UK

09:15-09:35

Title: A Versatile Evaluation on the Potential of Valeriana Species Against Insomnia

Dr. Burcu Sen, Associate Professor, Istanbul University, Turkey

09:35-09:55

Title: Invasiveness Inhibition and Actin Disintegration of Epithelial Cancer Cells by Cucurbitacin B

Dr. Cheng-Chen Huang, Professor, University of Wisconsin-River Falls, USA

09:55-10:15

Title: Drug Discovery of Anticancer with Nitrogen-carrying Constituents, Privileged Derivatives Which Originated from Pentacyclic Triterpenoids

Dr. Sithenkosi Mlala, Lecturer, University of Fort Hare, South Africa

10:15-10:30

Coffee Break

10:30-10:50

Title: Novel Strategy in Searching for Natural Compounds with Anti-Aging and Rejuvenating Potential

Dr. Andrey Koptyug, Associate Professor, Department of Engineering, Mid Sweden University, Sweden

10:50-11:10

Title: Anthocyanin-accumulated Bioengineered Tomatoes for Colorectal Cancer Prevention in Animal Models

Dr. Weiqun Wang, Professor & Director, Kansas State University, USA

11:10-11:30

Title: Phytochemical Screening and GC-MS Chemical Profiling of an Innovative Anti-cancer Herbal Formula (PHF6)

Dr. Mohammed Mousa Al-Zharani, Associate Professor, Imam Mohammad Ibn Saud Islamic University, Saudi Arabia

11:30-11:50

Title: To Treat Psoriasis, Chinese Herbal Medicine Cannot be Absent 

Dr. Sheng-Jie Yu, Associate Fellow / Assistant Professor, Taichung Veterans General Hospital / National Chung Hsing University, Taiwan

IDDST 13: Biotherapy & Oncology Research

Time: 08:30-11:20, May 24, 2024 (Friday); Place: Yamato-B, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Qing Chen, Associate Scientific Director, Amgen Inc., USA

08:30-08:35

Chair's Introduction

08:35-09:00

Session Keynote Speech

Title: Peptide Nanocarriers Co-delivering an Antisense Oligonucleotide and Photosensitizer Elicit Synergistic Cytotoxicity

Dr. Cornelia G. Palivan, Professor, University of Basel, Switzerland

09:00-09:25

Title: Integral Membrane Proteins as Drug Targets: Challenges and Applications

Dr. Qing Chen, Associate Scientific Director, Amgen Inc., USA

09:25-09:50

Title: Human Heavy Chain Only Transgenic, Source of Single Domain Antibodies Building Blocks for Diagnostic and Therapeutic Application

Dr. Dubravka Drabek, Senior Scientist & Principal Investigator, Cell Biology Department Erasmus MC/Harbour Biomed, the Netherlands

09:50-10:15

Title: Precancerous and Cancerous Lesions of Aral Cavity: Prevention and New Therapeutic Solutions

Dr. Paolo Brunamonti Binello, Professor, University of Genoa, Italy

10:15-10:30

Coffee Break

10:30-10:55

Title: Lessons Learned from Donor Cell-derived Myeloid Neoplasms after Allogenic Hematopoietic Cell Transplantation

Dr. Katalin Kelemen, Professor, Mayo Clinic, USA

10:55-11:20

Title: The Influence of the Microbiome on Immunotherapy for Gastroesophageal Cancer

Dr. Moses S. Raj, Senior Attending, Allegheny Health Network Cancer Institute, USA

IDDST 14: Drug Bioprocessing & Manufacturing and Integrative Services

Time: 08:30-09:50, May 24, 2024 (Friday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay

Chair 

Mr. Richard Denk, Senior Consultant, SKAN AG, Switzerland    

08:30-08:35

Chair's Introduction

08:35-09:00

Title: QbD in Biopharmaceutical Manufacturing and Biosimilar Development

Dr. Christina Vessely, Senior Consultant, Biologics Consulting Group, Inc., USA

09:00-09:25

Title: Points to Consider for the Commercial Manufacturing of Cell & Gene Therapies

Mr. Richard Denk, Senior Consultant, SKAN AG, Switzerland 

09:25-09:50

Title: Pricing and Reimbursement of Regenerative Medicine Products in Japan

Ms. Na Wei, Partner, Simon-Kucher & Partners, Japan

IDDST 15: Young Scientist' Forum

Time: 10:30-11:55, May 24, 2024 (Friday); Place: Yoshino, 5F, Grand Prince Hotel Osaka Bay

Chair

Mr. Richard Denk, Senior Consultant, SKAN AG, Switzerland

10:30-10:35

Chair's Introduction

10:35-10:55

Title: The Decline in Cellular Iron Content is a Crucial Element for the Execution of the Differentiation Program in Cultured Keratinocytes

Mr. Junya Abe, Student, Kwansei Gakuin University, Japan

10:55-11:15

Title: DP-independent E2F Activity as a Target of Cancer Specific Therapeutics

Ms. Rinka Nakajima, Graduate Student, Kwansei Gakuin University, Japan

11:15-11:35

Title: Acute Toxicity and Biodistribution of Iron-quercetin Complex, A New MRI Contrast Agent

Ms. Phattarawadee Innuan, Master Student, Chiang Mai University, Thailand

11:35-11:55

Title: TP53 Status is a Potential Predictive Marker for Efficacy of Glioblastoma Stem Cells Radiosensitisation by Chloroquine

Mr. Andreas Muller, PhD Student, Laboratory of Experimental Neurooncology, Clinic for Neurosurgery, Johannes Gutenberg Medical University Mainz, Germany

IDDST 16: Video Forum

1

Title: Artificial Intelligence (AI) and Alternative Variables (AV) in Drug Discovery: A Promising Alliance

Dr. Celerino Abad-Zapatero, Research Professor, Institute for Tuberculosis Research, University of Illinois Chicago, USA

2

Title: Nutrition and Healthy

Dr. Rong Liu, Professor, Nanjing Agricultural University, China

3

Title: Modeling of the Composition of Polymer Films, Production, And Quality Assessment

Dr. Modestas Zilius, Researcher, Lithuanian University of Health Sciences, Lithuania

4

Title: New Thinking in Clinical Trials: The Estimand Journey

Dr. Christine Fletcher, Vice President Biostatistics, GSK, UK

5

Title: Biomarkers of Brain Network Function in Drug Development:  AI-informed Heuristic and Target Predictions Using EEG Tomography in Nonhuman Primates and Humans

Dr. Monica Metea, Founder/Consultant, Preclinical Electrophysiology Consulting, LLC, USA

6

Title: Reclaiming African Indigenous Medicine and its Associated Value

Dr. Mandla S Makhanya, Professor, University of South Africa, South Africa

 

The 11th Annual International Symposium of Drug Delivery Systems (SDDS-2024)

 

SDDS 01: Novel Drug Delivery Technologies & Advanced Carriers Materials

Time: 08:30-12:10, May 23, 2024 (Thursday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Dan Myers, Vice President, Product Research & Development, Alexza Ferrer, USA

08:30-08:35

Chair's Introduction

08:35-09:00

Title: Targeted Drug Delivery Is the Main Challenge in Nanomedicine

Dr. Sandor G. Vari, Director, Cedars-Sinai Medical Center, USA

09:00-09:25

Title: Liposomal Delivery for Potentiated STING Activation

Dr. Chalet Tan, Professor, The University of Tennessee Health Science Center, USA

09:25-09:50

Title: The Staccato™ System: A Novel Approach for Treatment of Acute Conditions

Dr. Dan Myers, Vice President, Product Research & Development, Alexza Ferrer, USA

09:50-10:15

Title: Transethosome-Encapsulated Bouea macrophylla Seed Extract for Anti-Acne Application: Response Surface Methodology, Antibacterial Efficacy, and Safety Assessment

Dr. Worrapan Poomanee, Assistant Professor, Chiang Mai University, Thailand

10:15-10:30

Coffee Break

10:30-10:55

Title: Applications of Calcium Ion-induced Quercetin Nanoemulsion Gel-Forming Eye Drops for Delaying Degeneration of Eye Lens

Dr. Rathapon Asasutjarit, Associate Professor, Thammasat University, Thailand

10:55-11:20

Title: Use of Selective Laser Sintering for 3D Printing of Oral Dosage Forms

Dr. Jonas Lindh, Associate Professor, Uppsala University, Sweden

11:20-11:45

Title: PharmaJet - Leading a Transformation on How Medicines Harness the Full Power of the Immune System

Mr. Chris Cappello, President & CEO, PharmaJet Inc., USA

11:45-12:10

Title: The Effect of Centella Asiatica on Wound Healing and Immune System

Dr. Elena Arribas-Lopez, Lecturer/Researcher, University of Greenwich, UK

 

SDDS 02: Targeted Drug Delivery & Drug Formulation

Time: 13:30-16:50, May 23, 2024 (Thursday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Miriam Kidron, Chief Scientific Officer and Director, Oramed Pharmaceuticals, Israel

13:30-13:35

Chair's Introduction

13:35-13:55

Title: Inhaled Chemotherapies as Potential New Locoregional Modality to Increase the Immune Therapy Response in Lung Cancer Treatment

Dr. Nathalie Wauthoz, Professor, Université Libre de Bruxelles, Belgium

13:55-14:15

Title: Pathway for Formulation Development from Discovery to Phase I Clinical Formulation

Dr. Elizabeth Kwong, Consultant, Kwong Eureka Solutions, Canada

14:15-14:35

Title: Ad Hoc Analysis to Optimize Eligibility of Patients with Type 2 Diabetes Mellitus for Oral Insulin Treatment

Dr. Miriam Kidron, CSO, Oramed Pharmaceuticals, Israel

14:35-14:55

Title: Interaction Effects Assessment Between Siloxanes and Human Stratum Corneum and Impact on Skin Barrier

Dr. Krystyna Mojsiewicz-Pienkowska, Assistant Professor, Medical University of Gdansk, Poland

14:55-15:15

Title: Advancing Lipid-Based Formulations and Softgels in Drug Development.

Dr. Masataka Katsuma, Director, Product Development, Catalent Japan Co., Ltd., Japan

15:15-15:30

Coffee Break

15:30-15:50

Title: The Opportunity for Dry Powder Intranasal Drug Delivery: Formulation and Device Considerations

Lucas Silva, Senior Specialist for OINDP Analytical Development, Nanopharm, An Aptar Pharma Company, UK

15:50-16:10

Title: Targeted Delivery of TGFβ mRNA to Lung Parenchyma Using One-component Ionizable Amphiphilic Janus Dendrimers

Dr. Elena Atochina-Vasserman, Research Assistant Professor, University of Pennsylvania, USA

16:10-16:30

Title: Microsampling Skin Tissue: Advancements in Drug Measurements for Skin Disease Management, Topical Application, and Enhancement

Dr. Tarl Prow, Professor, Director, Skin Research Centre, Hull York Medical School, University of York, UK

16:30-16:50

Title: Advanced Transdermal Drug Delivery: Innovations in Physical Enhancement and Depth Control with Free-Form Design

Dr. Miko Yamada, Research Fellow, Hull York Medical School, University of York, UK

 

SDDS 03: Biotherapeutic Drug Delivery & Drug Delivery Systems for Major Diseases

Time: 08:30-11:45, May 24, 2024 (Friday); Place: Kamo, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Yuhua Li, Co-founder and SVP of R&D, Foresee Pharmaceuticals Co., Ltd., USA

08:30-08:35

Chair's Introduction

08:35-09:00

Title: Small Molecule-Based Therapies for Enhancing Bone Repair and Regeneration

Dr. Wai Hong (Kevin) Lo, Associate Professor, University of Connecticut Health Center, USA

09:00-09:25

Title: Stable Injectable Formulation for Sustained Release Delivery of Leuprolide for the Treatment of Advanced Prostate Cancer

Dr. Yuhua Li, Co-founder and SVP of R&D, Foresee Pharmaceuticals Co., Ltd., USA

09:25-09:50

Title: Use of Nucleoside-modified mRNA Encoding Regenerative Factors Encapsulated in Lipid Nanoparticles to Alleviate Acute and Chronic Murine Liver Diseases

Dr. Valerie Gouon-Evans, Associate Professor, Boston University School of Medicine, Boston Medical Center, USA

09:50-10:15

Title: Glymphatic System in Drug Delivery

Dr. Quan Jiang, Senior Scientist and Professor, Henry Ford Health & Michigan State University, USA

10:15-10:30

Coffee Break

10:30-10:55

Title: Development of Novel Phosphodiesterase 5 Inhibitors for the Therapy of Alzheimer's Disease

Dr. Ottavio Arancio, Professor, Columbia University, USA

10:55-11:20

Title: Enhancing PRIMA-1-mediated Restoration of Mutant p53 in Prostate Cancer Cells via CD24 Suppression

Dr. Runa Liu, Olivia Turlington Miller Endowed Chair of Cancer Genetics, Professor of Genetics, UAB Heeisink School of Medicine, USA

11:20-11:45

Title: Targeted Reactivation of X-linked Endogenous Genes in Human Female Breast Cancer Cells

Dr. Lizhong Wang, Professor, UAB School of Medicine, USA

 

SDDS 04: Video Forum

1

Title: Flexible IL-27 Based Immunotherapy Approaches for Bone Metastases

Dr. Marxa L. Figueiredo, Associate Professor, Basic Medical Sciences, Purdue University, USA

2

Title: Application of Freeze Drying Technology in the Production of Fast Melt Films containing Quetiapine Fumarate

Dr. Liew Kai Bin, Associate Professor, University of Cyberjaya, Malaysia

 

The 2nd World Chemistry Congress 2024 (IWCC-2024)

 

IWCC 01: Biochemistry, Organic and Medicinal Chemistry

Time: 08:30-12:10, May 23, 2024 (Thursday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Abul K Fazlur Rahman, Professor and Chair, The University of Oklahoma, USA

Co-Chair

Dr. Joanna Dulinska-Litewka, Chair, Jagiellonian University Medical College, Poland

08:30-08:35

Chair's Introduction

08:35-09:00

Title: The Intriguing Story of Carbocation and its Hyper-Valency

Dr. Abul K Fazlur Rahman, Professor and Chair, The University of Oklahoma, USA

09:00-09:25

Title: AI-Enhanced Capabilities in Research from Target to Drug Discovery: Challenges and Opportunities.

Dr. Jean Philippe Stephan, Senior Director, Institut de Recherches SERVIER, France

09:25-09:50

Title: Unique Nitric Oxide Synthesis Activities from Bacterial Nitric Oxide Synthases
Dr. Zhiqiang Molly Wang,
 Professor of Chemistry and Biochemistry Department, Kent State University, USA

09:50-10:15

Title: Modified Nanoparticles for Cancer Therapy
Dr. Joanna Dulinska-Litewka, Chair, Jagiellonian University Medical College, Poland

10:15-10:30

Coffee Break

10:30-10:55

Title: Affinity-Directed Site-Specific Protein Labeling and Its Application to Antibody-Drug Conjugates
Dr. Hyun Soo Lee, Professor, Sogang University, South Korea

10:55-11:20

Title: Structure-Cytotoxicity Relationship Study of Renieramycins Against Non-Small Cell Lung Cancer Cell Lines
Dr. Supakarn Chamni, Associate Professor, Chulalongkorn University, Thailand

11:20-11:45

Title: Advancements in Non-spherical Nanoparticle Synthesis through Initiated Chemical Vapor Deposition

Dr. Di Zhang, Postdoctoral Associate, Cornell University, USA

11:45-12:10

Title: A FRET-Based Respirasome Assembly Screen Identifies Spleen Tyrosine Kinase as A Target to Improve Muscle Mitochondrial Respiration and Exercise Performance in Mice
Dr. Ami Kobayashi, Research Fellow, Brigham & Women's Hospital, Ann Romney Center for Neurologic Diseases, USA

 

IWCC 02: Analytical, Inorganic & Physical Chemistry

Time: 13:30-17:30, May 23, 2024 (Thursday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Lili Zhang, Senior Scientist & Division Director, A*STAR, Singapore

Co-Chair

Dr. Waleed Saeed, Lead Geologist, Saudi Arabian Oil Company, Saudi Arabia.

13:30-13:35

Chair's Introduction

13:35-13:55

Title: Design, Optimization, and Construction of High-Performance Potassium-Ion Battery Electrodes

Dr. Hsing-Yu Tuan, Professor, NTHU, Taiwan--Keynote speech

13:55-14:15

Title: Engineering Multifunctional Inorganic Materials for Sustainable Catalysis
Dr. Lili Zhang, Senior Scientist & Division Director, A*STAR, Singapore

14:15-14:35

Title: Surface Modifications and Coatings in Chromatography

Dr. Kazuo Watanabe, SilcoTek Corporation, Japan

14:35-14:55

Title: Systematic Evaluation of the Application of Wireless Devices for Water Analysis in a Campus Storm Water Management Program

Dr. Wai Man (Karno) Ng, Associate Professor, California State University San Marcos, USA

14:55-15:15

Title: Hydroformylation: a Synergy of Academic and Industrial Chemistry

Dr. Baoxin Zhang, Research Scientist, Leibniz Institute for Catalysis, Germany

15:15-15:30

Coffee Break

15:30-15:55

Title: Laboratory Experiments to Evaluate the Effectiveness of Persulfate to Oxidize BTEX in Saline Environment and at Elevated Temperature Using Stable Isotopes

Dr. Waleed Saeed, Lead Geologist, Saudi Arabian Oil Company, Saudi Arabia

15:55-16:20

Title: The Development of Chemical Methods for Quality Control of Ziziphi Spinosae Semen
Dr. Siu-Po IP, Senior Researcher, The Chinese University of Hong Kong, China

16:20-16:45

Title: Using Artificial Intelligence (AI) to Combine Visible Near Infrared (Vis-NIR) Spectroscopy with Lab-Based Techniques for Predicting Nitrogen Levels in Leaves to Enhance Fertilizer Application in Bananas
Dr. Susan Parks, Remote Sensing Segment Manager, Malvern Panalytical Ltd., USA

16:45-17:10

Title: Monolithic Materials in Glycoprotein Analysis

Dr. Allan Jonson Alla, Senior Lecturer, University of Technology and Applied Sciences (UTAS) - Muscat, Oman

17:10-17:30

Title: Competitive or Sequential Reaction of an Electrophilic Terminal Phosphinidene Metal(0) Complex with Allyl Halides? [2+1]-Cycloaddition vs C-X Bond Insertion

Dr. Arif Ali Khan, Assistant Professor, Guru Gobind Singh Indraprastha University, India

17:30-17:50

Title: Advanced Thermal Management Materials for Electronic Packaging
Dr. Cheng-Te Lin, Professor, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, China

 

IWCC 03: Industrial and Green Chemistry

Time: 08:30-12:20, May 24, 2024 (Friday); Place: Tatsuta, 5F, Grand Prince Hotel Osaka Bay

Chair

Dr. Harold Boone, Research Director, The Dow Chemical, USA

Co-Chair

Dr. Nouf Al Jabri, King Abdullah University of Science and Technology, Saudi Arabia

08:30-08:35

Chair's Introduction

08:35-08:55

TitleLiquid Phase Nanostructuring and 2D Patterning of Metal Oxide Thin Films - TiO2, ZnO, Fe3O4, Ta2O5, SnO2 -
Dr. Yoshitake Masuda, Senior Research Scientist, National Institute of Advanced Industrial Science and Technology (AIST), Japan

08:55-09:15

Title: Decarbonize and Grow Challenges in Achieving Carbon Neutrality By 2050
Dr. Harold Boone,
 R&D Director, Dow Packaging & Specialty Plastics and Hydrocarbons, USA

09:15-09:35

Title: BioSensors for Sustainable Agriculture & the Environment
Dr. Alan O' Riordan, 
Senior Research Fellow, Tyndall National Institute, Ireland

09:35-09:55

Title: Innovative biomass based sustainable aviation fuel production process – A techno-economic and sustainability assessment

Dr. Ralph-Uwe Dietrich, R&D Manager, German Aerospace Center, Germany

09:55-10:15

Title: Lignin Vlarization Through Its Chemical Modification.

Dr. Byung-Dae Park, Professor, Kyungpook National University, South Korea

10:15-10:30

Coffee Break

10:30-10:50

Title: Electrocatalysis Using Main-Group-Element-based Molecular Catalysts
Dr. Jianbing Jiang, 
Associate Professor, University of Cincinnati, USA

10:50-11:20

Title: The Discovery of Bioactive Antioxidants in Wheat Brans for Retarding Skin- and Health-ageing
Dr. Kaori Kobayashi, 
Kansas State University, USA

11:20-11:40

Title: Tracers’ Development Journey to Iluminate Reservoirs: Case Studies and Futuristic Directions
Dr. Nouf Al Jabri,
 Saudi Aramco, Saudi Arabia

11:40-12:00

Title: Preliminary Topic of His Speech – Palladium Containing Catalysts in Chemical Synthesis Technologies

Dr. Dmitry Korolev, Lead manager, MMC Norilsk Nickel., Russia

12:00-12:20

Title: The Research of Assumption Principles of Deposition Potentials of Uranium and Uranium Alloys Formed with Fe/Co/Ni In Licl-Kcl At 773 K
Dr. Kewei Jiang, Associate Researcher, China Research Institute for Radiation Protection, China

 

 

Posters & Papers

IDDST 01  

Title: Antimicrobial Resistance among Bloodstream Pathogens, Antibiotic Consumption, and the Financial Burden and Impact on the Biggest Hospital in Bulgaria

Dr. Gergana Lengerova, Assistant Professor, Medical University of Plovdiv, Bulgaria

IDDST 02

Title: Biologically Synthesized Silver Nanoparticles as Potent Antibacterial Effective Against Multidrug-resistant Pseudomonas Aeruginosa

Dr. Ana Maria Fernandez-Presas, Principal Investigator, National Autonomous University of Mexico, Mexico

IDDST 03

Title: Antimicrobial and Anti-inflammatory Activity of Cystatin C on Human Gingival Fibroblast Incubated with Porphyromonas Gingivalis

Dr. Ana Maria Fernandez-Presas, Principal Investigator, National Autonomous University of Mexico, Mexico

 

 



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