IDDST-2024 (Europe)
Scientific Program

Day 1 | Day 2 | Day 3

 

IDDST 04: Cancers/Tumors

Time: 08:30-11:45, June 18, 2024 (Tuesday); Place: Juliet, 1F, Radisson Blu Beke Hotel

 

Chair

Dr. Eyal Talor, Chief Scientific Officer, CEL-SCI Corporation, USA; Johns Hopkins, Medical Institutions, USA

Co-Chair

Dr. Elizabeth Tran, Professor, Purdue University, USA

 

08:30-08:35

Chair’s Introduction

08:35-09:00

Title: Functions of DHEA in Relation to Breast Cancer

Dr. Robert T. Chatterton, Professor, Northwestern University, USA

09:00-09:25

Title: Neoadjuvant Immunotherapy for Head and Neck Cancer: Low Tumor PD-L1 Expression - IT-MATTERS – RCT

Dr. Eyal Talor, Chief Scientific Officer, CEL-SCI Corporation, USA; Johns Hopkins, Medical Institutions, USA

09:25-09:50

Title: Treatment of Advanced Carcinomas with Targeted Osmotic Lysis: A Clinical Perspective

Dr. Dennis Paul, Professor, LSU Health Sciences Center New Orleans, USA

09:50-10:15

Title: Duodenal Gastrinoma Associated with Multiple Endocrine Neoplasia Type 1 (MEN1) Detected by Esophagogastroduodenoscopy (EGD), which was Buried under Ulcer

Dr. Kenji Sasaki, Gastroenterologist, Midtown Medicare Clinic, Japan

10:15-10:30

Coffee Break

10:30-10:55

Title: Supinoxin blocks Small Cell Lung Cancer Progression by Inhibiting Mitochondrial Respiration through the RNA Helicase DDX5

Dr. Elizabeth Tran, Professor, Purdue University, USA

10:55-11:20

Title: TGF-β Induces miR-100 and miR-125b During Pancreatic Ductal Adenocarcinoma Progression

Dr. Leandro Castellano, Head, Department of Biochemistry and Biomedicine, University of Sussex, UK

11:20-11:45

Title: Cancer Decision Making in the Rural Sector

  A/Prof. Susan Pendlebury, Director of Radiation Oncology, North West Cancer Centre, Australia

 

IDDST 05: CNS and Neurodegenerative Drug Targets and Diseases

Time: 08:30-12:10, June 18, 2024 (Tuesday); Place: Romeo, 1F, Radisson Blu Beke Hotel

 

Chair

Dr. Wilfried Schupp, Senior Lecturer, Friedrich Alexander University, Germany

Co-Chair

Dr. Jie Zheng, Professor and Chair, Department of Chemical, Biomolecular, and Corrosion Engineering, University of Akron, USA (TBD)

 

08:30-08:35

Chair’s Introduction

08:35-09:00

Title: Pharmacotherapy for Obstructive Sleep Apnea

Dr. Nanduri R. Prabhakar, Professor, University of Chicago, USA

09:00-09:25

Title: Medication and Non-drug Therapies in Neurorehabilitation to Improve or Relearn Motor Functions and Movements

Dr. Wilfried Schupp, Senior Lecturer, Friedrich Alexander University Erlangen-Nuremberg, Germany

09:25-09:50

Title: Preclinical and Clinical Development of KM-819, the Proapoptotic Protein FAF1, as a Disease-Modifying Drug for Parkinson’s Disease and Multiple System Atrophy

Dr. Jae Moon Lee, President, Kainos Medicine Inc., South Korea; President, FAScinate Therapeutics, Inc., USA

09:50-10:15

Title: On the Enhancement of Antidepressant Effects of Hallucinogenic Drugs by mGlu2/3 Glutamate Receptors Antagonists

Dr. Andrzej Pilc, Professor, Institute of Pharmacology, Polish Academy of Sciences, Poland

10:15-10:30

Coffee Break

10:30-10:55

Title: Molecular Understanding and Evidences of Amyloid Cross-seeding

Dr. Jie Zheng, Professor and Chair, Department of Chemical, Biomolecular, and Corrosion Engineering, University of Akron, USA

10:55-11:20

Title: Lutein and Its Metabolites Modulate Inflammation, Oxidative Stress, and Lipid Peroxidation at Glutamate-induced Neurotoxicity

Dr. Ramóna Pap, Senior lecturer, University of Pécs, Hungary

11:20-11:45

Title: Challenge to Target Chameleon Proteins Hallmarking Parkinson’s Disease

Dr. Judit Oláh, Senior Scientist, HUN-REN Research Centre for Natural Sciences, Hungary

11:45-12:10

Title: Mechanistic Modeling of the Human Central Nervous System Pharmacokinetics to Inform Brain Cancer Drug Development and Therapy

Dr. Jing Li, Professor, Karmanos Cancer Institute, Wayne State University, USA

 

IDDST 06: Infectious Diseases

Time: 08:30-11:45, June 18, 2024 (Tuesday); Place: Venice, 1F, Radisson Blu Beke Hotel

 

Chair

Dr. Petr Maly, Head of Laboratory of Ligand Engineering, Institute of Biotechnology of Czech Academy of Sciences, Czech Republic

Co-Chair

Dr. Ravi V. Durvasula, Chair, Division of Infectious Diseases, Mayo Clinic, USA

 

08:30-08:35

Chair’s Introduction

08:35-09:00

Title: New Monoclonal Antibodies for Therapy of Malaria
Prof. Dr. Dr. Rolf G. Werner, Honorary Senator and Professor Industrial Biotechnology, Eberhard Karls University Tübingen, Germany; Pharma Consulting, Suzhou Industrial Park, China

09:00-09:25

Title: Development of Non-cognate Ligands of Broadly Neutralizing Antibody Paratopes as Potential Vaccine Antigens inducing Prevention Against Hepatitis C virus Infection

Dr. Petr Maly, Head, Laboratory of Ligand Engineering, Institute of Biotechnology of Czech Academy of Science, Czech Republic

09:25-09:50

Title: Hepatitis E Virus Infection: Circulation, Molecular Epidemiology, and Impact on Global Health

Mr. James Wai Kuo Shih, Senior Advisor, Xiamen Innovax Biotech Co., Ltd., China

09:50-10:20

Title: Global Impact of Leishmania Infections and New Approaches to Control

Dr. Ravi V. Durvasula, Chair, Division of Infectious Diseases, Mayo Clinic, USA

10:20-10:30

Coffee Break

10:30-10:55

Title: How to Conrol Epstein-Bar Virus in Long COVID Syndrome, and Other Diseases in Which it ist Involved

Dr. Gilbert Glady, President, EBMA France, France      

10:55-11:20

Title: Phage Therapy in Germany – An Overview
Dr. Justus Gross, Head of Vascular Surgery, Rostock University Medical Center, Germany

11:20-11:45

Title: Using Metabolomics for Improved Disease Characterization, Diagnostics and Treatment Strategies / New Drug Development Against Tuberculosis
Dr. Du Toit Loots, Professor, North-West University, South Africa

 

IDDST 07: Current Drug Discovery Technologies

Time: 13:30-16:45, June 18, 2024 (Tuesday); Place: Juliet, 1F, Radisson Blu Beke Hotel

 

Chair

Dr. Mark S. B McAlister, Director of Biophysics, AstraZeneca, UK

Co-Chair

Dr. Rebeca Ruiz, Principal Scientist, Pion Inc., UK

 

13:30-13:35

Chair’s Introduction

13:35-14:00

Title: Artificial Intelligence for Compound Pharmacokinetics Prediction

Dr. Olga Obrezanova, Director, Imaging and Data Analytics Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, UK

14:00-14:25

Title: Electrophile-first Covalent Drug Discovery for Intractable Targets

Dr. Mark S. B McAlister, Director of Biophysics, AstraZeneca, UK

14:25-14:50

Title: Protein-based Tools in Drug Screening. Case Studies from TargetEx Multi-Year Experience

Dr. Istvan Hajdu, Senior Scientist, TargetEx Biosciences Ltd., Hungary

14:50-15:15

Title: Qualified Hits for Challenging Targets: Identification and Characterization of Pocket-Specific Fragment Hits

Dr. Lars Neumann, Director Discovery Solutions, Proteros Biostructures GmbH, Germany

15:15-15:30

Coffee Break

15:30-15:55

Title: Strategies to Improve Solubility and Dissolution of Pharmaceutical Drugs in GI-media

Dr. Rebeca Ruiz, Principal Scientist, Pion Inc., UK

15:55-16:20

Title: Determination of Critical Quality Attributes and More of LNP with AF4 MALS

Ms. Sarka Bacovska, Field Application Scientist, Waters, Wyatt Technology, Czech Republic

16:20-16:45

Title: High Content Imaging to Enable Biologics Drug Discovery

Dr. James Dodgson, Associate Principal Scientist, AstraZeneca, UK

 

IDDST 08: Targeted Drug Delivery & Advanced Carriers Materials

Time: 13:30-17:00, June 18, 2024 (Tuesday); Place: Romeo, 1F, Radisson Blu Beke Hotel

 

Chair

Dr. Dongling Ma, Professor, Canada Research Chair (Tier 1) in Advanced Functional Nanocomposites, National Institute of Scientific Research, Canada

 

13:30-13:35

Chair’s Introduction

13:35-14:05

Title: Constructing Multifunctional Nanoplatforms for Biomedical Applications

Dr. Dongling Ma, Professor, Canada Research Chair (Tier 1) in Advanced Functional Nanocomposites, National Institute of Scientific Research, Canada

14:05-14:35

Title: Tumor Specific Delivery of Therapeutic Payloads Using a pH-Sensitive Nanoparticle Platform

Dr. Ruolan Han, Vice President, Nonclinical and Translational Research, OncoNano Medicine, Inc., USA

14:35-15:05

Title: Nasal Drug Delivery: How to Overcome Chemical, Physical, and Physiological Challenges

Mr. Hubert Pellikaan, Director / Pharmaceutical Product Development, Nextstep Pharma BV, The Netherlands

15:05-15:30 Coffee Break
15:30-16:00

Title: Poly(lactic-co-glycolic) Acid Nanoparticles as a Delivery System for Fish Oil: Characterization and Application for Cutaneous Wound Healing

Dr. Tomas Komprda, Professor, Mendel University in Brno, Czech Republic

16:00-16:30

Title: Fully Biocompatible Drug Carriers for Targeted Cancer Therapy

Dr. Markus Klapper, Head, Polymer Synthesis Group, Max-Planck Institute for Polymer Research, Germany

16:30-17:00

Title: Oral Absorption Assessment of Formulation-Enabled Etravirine Tablets: Deconvolution-Based Examination of Roles of Dissolution and Intestinal Permeation

Dr. Ayse Nur Oktay, Assistant Professor, University of Health Sciences, Turkey; Assistant Professor, University of Maryland, USA

 

IDDST 09: Digestive System Diseases

Time: 13:30-15:10, June 18, 2024 (Tuesday); Place: Venice, 1F, Radisson Blu Beke Hotel

 

Chair

Dr. Sandor Szabo, Founding Dean & Professor, School of Medicine, American University of Health Sciences, USA; External Member of the Hungarian Academy of Science

Co-Chair

Dr. Klara Gyires, Professor, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Hungary

 

13:30-13:35

Chair’s Introduction

13:35-14:00

Title: New Drugs & New Class of Steroids for the Upper & Lover Gi Tract

Dr. Sandor Szabo, Founding Dean & Professor, School of Medicine, American University of Health Sciences, USA

14:00-14:25

Title: Role of Phospholipids in Reducing the GI Toxicity and Increase the Bioiavailability of NSAIDs and Related Drugs

Dr. Lenard Lichtenberger, Professor of Emeritus, The University of Texas Health Science Center at Houston; Scientific Co-Founder, PLx Pharma Inc., USA

14:25-14:50

Title: The Somatostatin 4 Receptor Mediates Gastrointestinal Mucosal Protection

Dr. Zsuzsanna Helyes, Full Professor, Department of Pharmacology and Pharmacotherapy, University of Pécs, Medical School & Hungarian Research Network, Chronic Pain Research Group, Hungary

14:50-15:15

Title: Searching for New Targets for Treatment of NSAID Enteropathy

Dr. Zoltan S. Zadori, Associate Professor, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Hungary

15:15-15:30

Coffee Break

 

 



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