IDDST 04: Cancers/Tumors Time: 08:30-11:45, June 18, 2024 (Tuesday); Place: Juliet, 1F, Radisson Blu Beke Hotel |
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Chair |
Dr. Eyal Talor, Chief Scientific Officer, CEL-SCI Corporation, USA; Johns Hopkins, Medical Institutions, USA |
Co-Chair |
Dr. Elizabeth Tran, Professor, Purdue University, USA |
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08:30-08:35 |
Chair’s Introduction |
08:35-09:00 |
Title: Functions of DHEA in Relation to Breast Cancer Dr. Robert T. Chatterton, Professor, Northwestern University, USA |
09:00-09:25 |
Title: Neoadjuvant Immunotherapy for Head and Neck Cancer: Low Tumor PD-L1 Expression - IT-MATTERS – RCT Dr. Eyal Talor, Chief Scientific Officer, CEL-SCI Corporation, USA; Johns Hopkins, Medical Institutions, USA |
09:25-09:50 |
Title: Treatment of Advanced Carcinomas with Targeted Osmotic Lysis: A Clinical Perspective Dr. Dennis Paul, Professor, LSU Health Sciences Center New Orleans, USA |
09:50-10:15 |
Title: Duodenal Gastrinoma Associated with Multiple Endocrine Neoplasia Type 1 (MEN1) Detected by Esophagogastroduodenoscopy (EGD), which was Buried under Ulcer Dr. Kenji Sasaki, Gastroenterologist, Midtown Medicare Clinic, Japan |
10:15-10:30 |
Coffee Break |
10:30-10:55 |
Title: Supinoxin blocks Small Cell Lung Cancer Progression by Inhibiting Mitochondrial Respiration through the RNA Helicase DDX5 Dr. Elizabeth Tran, Professor, Purdue University, USA |
10:55-11:20 |
Title: TGF-β Induces miR-100 and miR-125b During Pancreatic Ductal Adenocarcinoma Progression Dr. Leandro Castellano, Head, Department of Biochemistry and Biomedicine, University of Sussex, UK |
11:20-11:45 |
Title: Cancer Decision Making in the Rural Sector A/Prof. Susan Pendlebury, Director of Radiation Oncology, North West Cancer Centre, Australia |
IDDST 05: CNS and Neurodegenerative Drug Targets and Diseases Time: 08:30-12:10, June 18, 2024 (Tuesday); Place: Romeo, 1F, Radisson Blu Beke Hotel |
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Chair |
Dr. Wilfried Schupp, Senior Lecturer, Friedrich Alexander University, Germany |
Co-Chair |
Dr. Jie Zheng, Professor and Chair, Department of Chemical, Biomolecular, and Corrosion Engineering, University of Akron, USA (TBD) |
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08:30-08:35 |
Chair’s Introduction |
08:35-09:00 |
Title: Pharmacotherapy for Obstructive Sleep Apnea Dr. Nanduri R. Prabhakar, Professor, University of Chicago, USA |
09:00-09:25 |
Title: Medication and Non-drug Therapies in Neurorehabilitation to Improve or Relearn Motor Functions and Movements Dr. Wilfried Schupp, Senior Lecturer, Friedrich Alexander University Erlangen-Nuremberg, Germany |
09:25-09:50 |
Title: Preclinical and Clinical Development of KM-819, the Proapoptotic Protein FAF1, as a Disease-Modifying Drug for Parkinson’s Disease and Multiple System Atrophy Dr. Jae Moon Lee, President, Kainos Medicine Inc., South Korea; President, FAScinate Therapeutics, Inc., USA |
09:50-10:15 |
Title: On the Enhancement of Antidepressant Effects of Hallucinogenic Drugs by mGlu2/3 Glutamate Receptors Antagonists Dr. Andrzej Pilc, Professor, Institute of Pharmacology, Polish Academy of Sciences, Poland |
10:15-10:30 |
Coffee Break |
10:30-10:55 |
Title: Molecular Understanding and Evidences of Amyloid Cross-seeding Dr. Jie Zheng, Professor and Chair, Department of Chemical, Biomolecular, and Corrosion Engineering, University of Akron, USA |
10:55-11:20 |
Title: Lutein and Its Metabolites Modulate Inflammation, Oxidative Stress, and Lipid Peroxidation at Glutamate-induced Neurotoxicity Dr. Ramóna Pap, Senior lecturer, University of Pécs, Hungary |
11:20-11:45 |
Title: Challenge to Target Chameleon Proteins Hallmarking Parkinson’s Disease Dr. Judit Oláh, Senior Scientist, HUN-REN Research Centre for Natural Sciences, Hungary |
11:45-12:10 |
Title: Mechanistic Modeling of the Human Central Nervous System Pharmacokinetics to Inform Brain Cancer Drug Development and Therapy Dr. Jing Li, Professor, Karmanos Cancer Institute, Wayne State University, USA |
IDDST 06: Infectious Diseases Time: 08:30-11:45, June 18, 2024 (Tuesday); Place: Venice, 1F, Radisson Blu Beke Hotel |
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Chair |
Dr. Petr Maly, Head of Laboratory of Ligand Engineering, Institute of Biotechnology of Czech Academy of Sciences, Czech Republic |
Co-Chair |
Dr. Ravi V. Durvasula, Chair, Division of Infectious Diseases, Mayo Clinic, USA |
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08:30-08:35 |
Chair’s Introduction |
08:35-09:00 |
Title: New Monoclonal Antibodies for Therapy of Malaria |
09:00-09:25 |
Title: Development of Non-cognate Ligands of Broadly Neutralizing Antibody Paratopes as Potential Vaccine Antigens inducing Prevention Against Hepatitis C virus Infection Dr. Petr Maly, Head, Laboratory of Ligand Engineering, Institute of Biotechnology of Czech Academy of Science, Czech Republic |
09:25-09:50 |
Title: Hepatitis E Virus Infection: Circulation, Molecular Epidemiology, and Impact on Global Health Mr. James Wai Kuo Shih, Senior Advisor, Xiamen Innovax Biotech Co., Ltd., China |
09:50-10:20 |
Title: Global Impact of Leishmania Infections and New Approaches to Control Dr. Ravi V. Durvasula, Chair, Division of Infectious Diseases, Mayo Clinic, USA |
10:20-10:30 |
Coffee Break |
10:30-10:55 |
Title: How to Conrol Epstein-Bar Virus in Long COVID Syndrome, and Other Diseases in Which it ist Involved Dr. Gilbert Glady, President, EBMA France, France |
10:55-11:20 |
Title: Phage Therapy in Germany – An Overview |
11:20-11:45 |
Title: Using Metabolomics for Improved Disease Characterization, Diagnostics and Treatment Strategies / New Drug Development Against Tuberculosis |
IDDST 07: Current Drug Discovery Technologies Time: 13:30-16:45, June 18, 2024 (Tuesday); Place: Juliet, 1F, Radisson Blu Beke Hotel |
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Chair |
Dr. Mark S. B McAlister, Director of Biophysics, AstraZeneca, UK |
Co-Chair |
Dr. Rebeca Ruiz, Principal Scientist, Pion Inc., UK |
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13:30-13:35 |
Chair’s Introduction |
13:35-14:00 |
Title: Artificial Intelligence for Compound Pharmacokinetics Prediction Dr. Olga Obrezanova, Director, Imaging and Data Analytics Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, UK |
14:00-14:25 |
Title: Electrophile-first Covalent Drug Discovery for Intractable Targets Dr. Mark S. B McAlister, Director of Biophysics, AstraZeneca, UK |
14:25-14:50 |
Title: Protein-based Tools in Drug Screening. Case Studies from TargetEx Multi-Year Experience Dr. Istvan Hajdu, Senior Scientist, TargetEx Biosciences Ltd., Hungary |
14:50-15:15 |
Title: Qualified Hits for Challenging Targets: Identification and Characterization of Pocket-Specific Fragment Hits Dr. Lars Neumann, Director Discovery Solutions, Proteros Biostructures GmbH, Germany |
15:15-15:30 |
Coffee Break |
15:30-15:55 |
Title: Strategies to Improve Solubility and Dissolution of Pharmaceutical Drugs in GI-media Dr. Rebeca Ruiz, Principal Scientist, Pion Inc., UK |
15:55-16:20 |
Title: Determination of Critical Quality Attributes and More of LNP with AF4 MALS Ms. Sarka Bacovska, Field Application Scientist, Waters, Wyatt Technology, Czech Republic |
16:20-16:45 |
Title: High Content Imaging to Enable Biologics Drug Discovery Dr. James Dodgson, Associate Principal Scientist, AstraZeneca, UK |
IDDST 08: Targeted Drug Delivery & Advanced Carriers Materials Time: 13:30-17:00, June 18, 2024 (Tuesday); Place: Romeo, 1F, Radisson Blu Beke Hotel |
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Chair |
Dr. Dongling Ma, Professor, Canada Research Chair (Tier 1) in Advanced Functional Nanocomposites, National Institute of Scientific Research, Canada |
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13:30-13:35 |
Chair’s Introduction |
13:35-14:05 |
Title: Constructing Multifunctional Nanoplatforms for Biomedical Applications Dr. Dongling Ma, Professor, Canada Research Chair (Tier 1) in Advanced Functional Nanocomposites, National Institute of Scientific Research, Canada |
14:05-14:35 |
Title: Tumor Specific Delivery of Therapeutic Payloads Using a pH-Sensitive Nanoparticle Platform Dr. Ruolan Han, Vice President, Nonclinical and Translational Research, OncoNano Medicine, Inc., USA |
14:35-15:05 |
Title: Nasal Drug Delivery: How to Overcome Chemical, Physical, and Physiological Challenges Mr. Hubert Pellikaan, Director / Pharmaceutical Product Development, Nextstep Pharma BV, The Netherlands |
15:05-15:30 | Coffee Break |
15:30-16:00 |
Title: Poly(lactic-co-glycolic) Acid Nanoparticles as a Delivery System for Fish Oil: Characterization and Application for Cutaneous Wound Healing Dr. Tomas Komprda, Professor, Mendel University in Brno, Czech Republic |
16:00-16:30 |
Title: Fully Biocompatible Drug Carriers for Targeted Cancer Therapy Dr. Markus Klapper, Head, Polymer Synthesis Group, Max-Planck Institute for Polymer Research, Germany |
16:30-17:00 |
Title: Oral Absorption Assessment of Formulation-Enabled Etravirine Tablets: Deconvolution-Based Examination of Roles of Dissolution and Intestinal Permeation Dr. Ayse Nur Oktay, Assistant Professor, University of Health Sciences, Turkey; Assistant Professor, University of Maryland, USA |
IDDST 09: Digestive System Diseases Time: 13:30-15:10, June 18, 2024 (Tuesday); Place: Venice, 1F, Radisson Blu Beke Hotel |
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Chair |
Dr. Sandor Szabo, Founding Dean & Professor, School of Medicine, American University of Health Sciences, USA; External Member of the Hungarian Academy of Science |
Co-Chair |
Dr. Klara Gyires, Professor, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Hungary |
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13:30-13:35 |
Chair’s Introduction |
13:35-14:00 |
Title: New Drugs & New Class of Steroids for the Upper & Lover Gi Tract Dr. Sandor Szabo, Founding Dean & Professor, School of Medicine, American University of Health Sciences, USA |
14:00-14:25 |
Title: Role of Phospholipids in Reducing the GI Toxicity and Increase the Bioiavailability of NSAIDs and Related Drugs Dr. Lenard Lichtenberger, Professor of Emeritus, The University of Texas Health Science Center at Houston; Scientific Co-Founder, PLx Pharma Inc., USA |
14:25-14:50 |
Title: The Somatostatin 4 Receptor Mediates Gastrointestinal Mucosal Protection Dr. Zsuzsanna Helyes, Full Professor, Department of Pharmacology and Pharmacotherapy, University of Pécs, Medical School & Hungarian Research Network, Chronic Pain Research Group, Hungary |
14:50-15:15 |
Title: Searching for New Targets for Treatment of NSAID Enteropathy Dr. Zoltan S. Zadori, Associate Professor, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Hungary |
15:15-15:30 |
Coffee Break |
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