BIT's 18th Annual Congress of International Drug Discovery Science and Technology (IDDST-2020)
Scientific Program

Day 1 | Day 2 | Day 3

 

Session 212: Frontiers in Pharmacology and Toxicology 

Day 2: Morning, July. 16, 2021

Chair

Dr. Roberta Bursi, Vice President Model-Informed Drug Discovery Development, Vice President Acting Head Medical Devices, InsilicoTRIALS, Italy

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Title: InSilicoTrials.com: The Cloud Platform that Accelerates the Uptake of Computer Simulations for Testing Medicines and Medical Devices

Dr. Roberta Bursi, Vice President Model-Informed Drug Discovery Development, Vice President Acting Head Medical Devices, InsilicoTRIALS, Italy

09:00-09:25

Title: Opioid Therapy; When it is Caring and when it is Crippling?

Dr. Olfat Zekry, Pharmacology Unit Coordinator, Pain Education Unit, Pain Management Research Institute, Sydney Medical School, The University of Sydney, Australia

09:25-09:50

Speech Opportunity Available
Abstract and Biography: Submit Here

09:50-10:15

Title: Successful Outcome Following a Loading Dose of N-acetylcysteine to Treat Hepatotoxicity after Repeated Therapeutic Doses of Paracetamol

Dr. Abdullah Altamimi, Children hospital –King Fahad Medical City, Saudi Arabia

10:15-10:30

Coffee Break

10:30-10:55

Speech Opportunity Available
Abstract and Biography: Submit Here

10:55-11:20

Title: Strategically Developing and Utilizing CDX and PDX Models for Supporting Anticancer Drug Development

Dr. Jingqi Huang, Vice President of Pharmacology, Pharmaron, China

11:20-11:45

Title: Pharmacochaperoning of Neurotransmitter Transporters in Health and Disease

Dr. Sonja Sucic, Associate Professor, Medical University of Vienna, Australia

11:45-12:10

Title: Ketamine/Propofol Admixture (“KETOFOL”) for Sedation: The Real Deal or Not?

Dr. Nathan J Smischney, Assistant Professor, Department of Anesthesiology, Mayo Clinic, USA

 

Session 222: Novel Analytical Technology in Drug Discovery   

Day 2: Morning, July. 16, 2021

Chair

Dr. Anthony W. Coleman, Professor, University of Lyon, France

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Title: Electrophoretic Separation of Membrane Proteins in Supported n-bilayers: a Step toward a New Drug Discovery Platform

Dr. Bernard Tinland, Research Director, CINaM - CNRS UMR 7325, France

09:00-09:25

Speech Opportunity Available
Abstract and Biography: Submit Here

09:25-09:50

Title: The use of Multidisciplinary Research to Understand Bio-macromolecule Interactions with APIs

Dr. Anthony W. Coleman, Professor, University of Lyon, France

09:50-10:15

Title: TBD

Dr. Jenny Lin, Chief Operating Officer, CMIC, USA

10:15-10:30

Coffee Break

10:30-10:55

Speech Opportunity Available
Abstract and Biography: Submit Here

10:55-11:20

Title: Characterization of Nanomaterials in Liquid Phase Using Particle Tracking Analysis Method

Dr. Haruhisa Kato, Senior Researcher, National Metrology Institute of Japan (NMIJ),National Institute of Advanced Industrial Scienceand Technology (AIST), Japan

11:20-11:45

Title: TBD

Dr. Beom-Su Jang, Principal Investigator, Korea Atomic Energy Research Institute, South Korea

11:45-12:10

Title: Determination of Dynamic Binding Capacity of Ion Channel Protein with Small Molecules by the Bio-layer Interferometry Assay

Dr. Shangwei Hou, Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, China

 

Session 312: CNS and Neurodegenerative Drug Targets   

Day 2: Morning, July. 16, 2021

Chair

Call for Chair

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Title: Conventional and Advanced Imaging Biomarkers in Multiple Sclerosis Clinical Trials

Dr. Daniel Bradley, Associate Director, Biogen, USA

09:00-09:25

Title: TBD

Dr. Miroslaw Latka, Assistant Professor, Wroclaw University of Science and Technology, Poland

09:25-09:50

Title: TBD

Dr. Hua Xu, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, China

09:50-10:15

Speech Opportunity Available
Abstract and Biography: Submit Here

10:15-10:30

Coffee Break

 

Session 322: Drug Design and Synthesis 

Day 2: Morning, July. 16, 2021

Chair

Dr. Sonali Rudra, Senior Principal Research Scientist, TCG Lifesciences Pvt. Ltd., India

  Co-Chair   Dr. Didier Dubreuil, Professor, University of Nantes, France

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Speech Opportunity Available
Abstract and Biography: Submit Here

09:00-09:25

Title: iNKT Activation by Fluorinated Galactosylceramides

Dr. Didier Dubreuil, Professor, University of Nantes, France

09:25-09:50

Title: Novel Impiridones: Snthesis, Anticancer Activity and Structure-activity Relationships

Dr. Antal Csampai, Professor, Institute of Chemistry, Eotvos Lorand University (ELTE), Hungary

09:50-10:15

Speech Opportunity Available
Abstract and Biography: Submit Here

10:15-10:30

Coffee Break

10:30-10:55

Title: EP4 Antagonists for Treatment against Cancer

Dr. Sonali Rudra, Senior Principal Research Scientist, TCG Lifesciences Pvt. Ltd., India

10:55-11:20

Title: Metabotropic Glutamate Receptor type 2 Positive Allosteric Modulators (mGlu2 receptor PAMs) as a Transformational Epilepsy Treatment

Dr. Jose Maria Cid Nunez, Professor, Janssen Research and Development, Spain

11:20-11:45

Title: TBD

Dr. Salvatore Guccione, Professor, Central Drug Research Institute, Italy

11:45-12:10

Title: TBD

Dr. Nick Zhang, Chairman & CEO, MEDCDx (SuZhou) Translational Medicine Co. Ltd, China

 

Session 412: CNS Diseases   

Day 2: Morning, July. 16, 2021

Chair

Dr. Paolo Milia, Neurologist, University of Perugia, Italy

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Title: TBD 

Dr. Joan Fallon, CEO, Curemark, USA

09:00-09:25

Speech Opportunity Available
Abstract and Biography: Submit Here

09:25-09:50

Title: TBD 

Dr. Paolo Milia, Neurologist, University of Perugia, Italy

09:50-10:15

Title: A Child with Headache Attributed to Intracranial Neoplasm

Dr. Fusun Ferda Erdogan, Professor, Erciyes University, Turkey

10:15-10:30

Coffee Break

  10:30-10:55

Speech Opportunity Available
Abstract and Biography: Submit Here

  10:55-11:20

Title: ‘Early Onset Alzheimer’s Disease from Clinical to Basic Science

Dr. Popuri M. Krishna, Department of Psychiatry, Northern Ontario School of Medicine Psychiatry Department, Canada

  11:20-11:45

Title: Magnetic Navigation of Biodegradable Polymer-encapsulating Nanoparticles and Erythropoietin in Acute Central Nervous System Injury

Dr. Chang Ho Hwang, Affiliated Professor, School of Electrical Engineering, University of Ulsan, South Korea

  11:45-12:10

Speech Opportunity Available
Abstract and Biography: Submit Here

 

Session 422: Therapeutic Antibodies and Vaccines

Day 2: Morning, July. 16, 2021

Chair

Dr. Mahmood Moshiri, President and CEO, Next Pharma Inc., Canada

  Co-Chair   Dr. Thomas Boldicke, Professor, Helmholtz-Centre for Infection Research, Germany

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Title: Aspartyl (Asparaginyl) β-Hydroxylase (Aabh-Based Monitoring of Cancer Remission/Recurrence)

Dr. Mahmood Moshiri, President and CEO, Next Pharma Inc., Canada 

09:00-09:25

Title: Comprehensive Host Cell Protein Analytical Solutions using Immunoassays and Mass Spectrometry

Dr. Andrew Hanneman, Associate Director, Mass Spectrometry, Charles River Laboratories, USA

09:25-09:50

Title: Antibodies directed against Complex Target Molecules

Dr. Annika Schmid, Associate Director and Leader Discovery Programs, Morphosys AG, Germany

09:50-10:15

Title: Development of Intracellular Antibodies Targeting Cancer Antigens

Dr. Thomas Boldicke, Professor, Helmholtz-Centre for Infection Research, Germany

10:15-10:30

Coffee Break

10:30-10:55

Title: Recent Advances in ab initio Design of Antibodies Against Novel Targets

Dr. Monica Berrondo, CEO, Macromoltek - Molecular simulations simplified, USA

10:55-11:20

Title: Development of a Therapeutic Bispecific Antibody VEGF-PD-L1: Process Development and Non-clinical Studies

Dr. Xiang Yang Zhu, CEO, Huabo Biopharm (Shanghai) Co., Ltd., China

11:20-11:45

Title: Techniques for Selection and Verification of Highly Specific Antibodies

Dr. Nileena Velappan, Researcher, Los Alamos National Laboratory, USA

11:45-12:10

 Speech Opportunity Available
Abstract and Biography: Submit Here

 

Session 441: New Challenges in Future Pharma Manufacturing    

Day 2: Morning, July. 16, 2021

Chair

Call for Chair

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Speech Opportunity Available
Abstract and Biography: Submit Here

09:00-09:25

Title: Navigating through the Critical Path for Chemistry, Manufacturing and Controls (CMC)

Dr. Elizabeth Kwong, President, Kwong Eureka Solutions, Canada

09:25-09:50

Title: Selection and Development of Sterilization Processes

Dr. Jeanne Moldenhauer, Vice President, Excellent Pharma Consulting, Excellent Pharma Consulting, USA

09:50-10:15

Title: TBD

Dr. Cornelia Thieme, Director, Global Manufacturing Sciences, Biogen, Switzerland

10:15-10:30

Coffee Break

 

Session 442: Novel Biosimilars   

Day 3: Morning, July. 17, 2021

Chair

Dr. Andreas Seidl, Chief Operating Officer, LEUKOCARE AG, Germany

Time

 

08:30-08:35

Chair's Introduction

08:35-09:00

Speech Opportunity Available
Abstract and Biography: Submit Here

09:00-09:25

Title: Biosimilars in Europe, A Blueprint for Success

Dr. Michael Reilly, Executive Director, Alliance For Safe Biologic Medicines, USA

09:25-09:50

Title: Innovative Formulation Strategies to Differentiate Biosimilars

Dr. Andreas Seidl, Chief Operating Officer, LEUKOCARE AG, Germany

09:50-10:15

Title: TBD

Mr. Andrew Spiegel, Executive Director, Global Colon Cancer Association, USA

10:15-10:30

Coffee Break

  10:30-10:55

Speech Opportunity Available
Abstract and Biography: Submit Here

  10:55-11:20

Title: Biobetters: Using Innovation to Reap IP and Market Advantages over Competing Biosimilars in the U.S

Dr. Robert V. Cerwinski, Partner, Goodwin Procter LLP, USA

  11:20-11:45

Title: TBD

Dr. Leandro Gabriel Mieravilla, Global Manager, Cassara Biotech, Canada

 

Session 213: Drug Metabolism and Interactions

Day 2: Afternoon, July. 16, 2021

Chair

Dr. Gianluca Catucci, University of Torino, Italy

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Title: In-silico Methodology that Outperforms Lab Methods in Predicting Human Clinical ADME/PK

Dr. Urban Fagerholm, CEO, PROSILICO, Sweden

14:00-14:25

Title: The Biochemistry of Human Flavin-containing Monooxygenases: Implications for Drug Metabolism

Dr. Gianluca Catucci, University of Torino, Italy

14:25-14:50

Speech Opportunity Available
Abstract and Biography: Submit Here

14:50-15:15

Title: Impact of Conjugated Flavonoid Metabolites on Drug Transporters and Biotransformation Enzymes

Dr. Agnes Telbisz, Senior Research Fellow, Institute of Enzymology, RCNS-HAS, Hungary

15:15-15:30

Coffee Break

  15:30-15:55

Title: In Vivo/ex Vivo Monitoring of Drug-Drug Interactions in the Physiological Barriers

Dr. Franciska Erd, Senior Scientist, Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Hungary

  15:55-16:20

Title: Modelling Inactivation Parameters From Time-Dependent Inhibition Improves Clinical DDI Prediction Compared to Standard Practice

Dr. Jaydeep Yadav, Scientist, Pharmacokinetics and Drug Metabolism, Amgen, Inc., USA

  16:20-16:45

Title: Radiation Drug Interactions with an Emphasis on the Interactive Toxic and Therapeutic Effects of Radiation Therapy and Tyrosine Kinase Inhibitors

Dr. Gerald Sokol, Associate Professor of Medicine and Clinical Pharmacology, USUHS, USA

  16:45-17:10 Speech Opportunity Available
Abstract and Biography: Submit Here

 

Session 223: Nanotechnology in Drug Discovery

Day 2: Afternoon, July. 16, 2021

Chair

Call for Chair

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Title: TBD

Dr. Philippe Tschopp, Head of Business Development, Glatt Pharmaceutical Services GmbH & Co. KG, Germany

14:00-14:25

Title: TBD

Dr. Imran Y. Saleem, Professor, Liverpool John Moores University, Programme Leader in MSc Cosmetic, UK

14:25-14:50

Title: Folate and Antifolate SERS-active Nanovectors: Quantitative Drug Nanostructuring and Selective Cell Targeting for Effective Theranostics

Dr. Fabio Domenici, Assistant Professor, Department of Chemical Sciences and Technology, University of Rome, Italy

14:50-15:15

Speech Opportunity Available
Abstract and Biography: Submit Here

15:15-15:30

Coffee Break

 

Session 313: Autoimmune and Inflammation Drug Targets

Day 2: Afternoon, July. 16, 2021

Chair

Dr. Joseph Holoshitz, Professor of Internal Medicine, Division of Rheumatology, University of Michigan School of Medicine, USA 

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Keynote Speech

Title: New Technologies using Immune Cells to Inform on Human Disease Status

Dr. John J. Miles, Professor, James Cook University, Australia

14:00-14:25

Title: A New Therapeutically-Targetable Pathway in Rheumatoid Arthritis

Dr. Joseph Holoshitz, Professor of Internal Medicine, Division of Rheumatology, University of Michigan School of Medicine, USA

14:25-14:50

Title: Microglia and Mast Cells Generate Proinflammatory Cytokines in the Brain and Worsen Inflammatory Status

Dr. Stefano Martinotti, Professor, Department of Medical, Oral and Biotechnologic Sciences, Università degli Studi G. d'Annunzio Chieti e Pescara, Italy

14:50-15:15

Title: Influence of Heat Shock Proteins in Individual Sensitivity of Human Neutrophils to Heat Stress

Dr. Victor F. Semenkov, Associate Professor, Department of Immunology, Pirogov Russian National Research Medical University, Russia

15:15-15:30

Coffee Break

15:30-15:55

Title: Role of Heat Shock Protein 90 in Autoimmune Inflammatory Rheumatic Diseases

Dr. Michal Tomcik, Associate Professor, Institute of Rheumatology, Czech Republic

15:55-16:20

Title: TBD

Dr. Petr Maly, Group Leader, Institute of Biotechnology of the Czech Academy of Sciences v.v.i., Czech Republic

16:20-16:45

Title: Immunoproteasome Inhibitors Affect Human Immune Cell Viability

Dr. Katrien Pletinckx, Head of Laboratory, Grünenthal GmbH, Germany

16:45-17:10

Speech Opportunity Available
Abstract and Biography: Submit Here

 

Session 323: Screening and Lead Optimization

Day 2: Afternoon, July. 16, 2021

Chair

Call for Chair

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Speech Opportunity Available
Abstract and Biography: Submit Here

14:00-14:25

Speech Opportunity Available
Abstract and Biography: Submit Here

14:25-14:50

Title: The Discovery and Characterisation of Highly Selective and in Vivo Capable Inhibitors of the Second Bromodomains of the BET Family of Proteins

Mr. Alex Preston, Scientific Leader, GSK, UK

14:50-15:15

Title: TBD

Dr. Zhenwei Su, Senior Scientist, Biomedicine Design, Pfizer, Inc., USA

15:15-15:30

Coffee Break

 

Session 413: Infectious Diseases

Day 2: Afternoon, July. 16, 2021

Chair

  Dr. Michael Ovadia, Professor, Tel Aviv University, Israel

Time

 

13:30-13:35

Chair's Introduction

13:35-13:55

Title: Chagas Disease Drug Discovery: Multiparametric Lead Optimization Through Collaborative Project

Dr. Gilles Courtemanche, Associate Director, Antimicrobials Unit, BIOASTER, France

13:55-14:15

Title: Cinnamon Fraction CEppt Iinhibits Human Influenza H1N1 and Bird Flu H5N1 Leading to Vaccination of the Animals

Dr. Michael Ovadia, Professor, Tel Aviv University, Israel

14:15-14:35

Title: Antibacterial Drug Discovery and Development Programs, Preclinical and Clinical Services at NIAID

Dr. Zuoyu Xu, Program Officer, Bacteriology and Mycology, National Institute of Allergy and Infectious Diseases (NIAID), NIH/DHHS, USA

14:35-14:55

Speech Opportunity Available
Abstract and Biography: 
Submit Here

14:55-15:15

Title: Nanoformulated PI3-Kinase Inhibitors to Prevent Infection – driven Liver Failure

Dr. Michael Bauer, Professor, Center for Sepsis Control and Care, University Hospital Jena, Germany

15:15-15:30

Coffee Break

15:30-15:50

Title: The Role of Wildlife in the Transmission of Parasitic Zoonoses in Peri-urban Areas

Dr. Ute Mackenstedt, Professor, Parasitology Unit, University of Hohenheim, Germany

15:50-16:10

Title: AMR: The Links Between Antibiotic Resistance and Disinfectant Resistance

Dr. Andrew Kemp, AK Medical Ltd, UK

16:10-16:30

Title: MazF toxin: A Magic potion for Bacterial Sleeping  Pan-coronavirus Fusion Inhibitors for Prevention and Treatment of COVID-19

Dr. Adriana Renzoni, Service of Infectious Diseases, University Hospital and Medical School of Geneva, Switzerland

16:30-16:50

Title: Pan-coronavirus Fusion Inhibitors for Prevention and Treatment of COVID-19

Dr. Shibo Jiang, Professor and Director, Institute of Medical Microbiology, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Fudan University, China

  16:50-17:10  Title: mcr-1, mcr-3 , Carbapenemase and CTX-M Genes in Carbapenemase Producing Klebsiella Pneumoniae Isolated from Humans in Thailand

Dr. Worada Samosornsuk, Associate Professor, Department of Medical Technology, Thammasat University, Thailand

17:10-17:30

Speech Opportunity Available
Abstract and Biography: 
Submit Here

 

Session 414: Cardiovascular Diseases      

Day 2: Afternoon, July. 16, 2021

Chair

Dr. Karin Schutze, CSO, CellTool GmbH, Germany

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Title: Quality Assurance for Cell based Therapeutics such as T-cells, Blood Products and 3D Tissues

  Dr. Karin Schutze, CSO, CellTool GmbH, Germany

14:00-14:25

Speech Opportunity Available
Abstract and Biography: 
Submit Here

14:25-14:50

  Speech Opportunity Available
  Abstract and Biography: 
Submit Here

14:50-15:15

Title: TBD 

Dr. Tamas Alexy, Department of Medicine, Division of Cardiology, University of Minnesota, USA

15:15-15:30

Coffee Break

  15:30-15:55

Title: Evidence of NLRP7 Direct Involvement in Gestational Choriocarcinoma Development: Clinical, in vitro and in vivo Investigations

Dr. Nadia Alfaidy, Senior Researcher, Director of research at INSERM, France

  15:55-16:20

Title: Anticoagulant and Antiplatelet Therapies for Children in the 21st Century ---- Their Challenges and Rewards

Dr. Masato Takahashi, Clinical Professor, U. Washington School of Medicine, USA

  16:20-16:45 Title: Trumanshow- A Screening Tool for Early Detection of Aortic Dissections in the Emergency Department 

Dr. Rama Subrahmanyam, Emergency Physician, University Hospitals of Leicester, UK

  16:45-17:10

Speech Opportunity Available
Abstract and Biography: Submit Here

 

Session 415: Diabetes and Other Metabolic Disorders

Day 2: Afternoon, July. 16, 2021

Chair

Dr. Miriam Kidron, CSO, Oramed Pharmaceuticals, Israel

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Title: Therapeutic Approaches for Non-Alcoholic Steatohepatitis (NASH)

Dr. Ralf Glatthar, Director, Novartis Pharma AG, Switzerland

14:00-14:25

Title: Overcoming the Barriers to Oral Insulin Development: A Point in Time Assessment

Dr. Miriam Kidron, CSO, Oramed Pharmaceuticals, Israel

14:25-14:50

Title: Is magnesium an Effective Prophylaxis against Recurrent Calcium Oxalate Nephrolithiasis?

Dr. Michel Normand, Nephrologist, Private Hospital, France

14:50-15:15

Title: Novel Screening Methods for Prediabetes and Type 2 Diabetes

Dr. Serge Bottari, Grenoble-Alps University, France

15:15-15:30

Coffee Break

15:30-15:55

Title: Primary Hyperoxaluria – A New Promising Treatment for a Fatal Disease

Dr. Elisabeth Lindner, President, OxThera, USA

15:55-16:20

Title: Changes in Trends of Epidemiological Data (Incidence, Prevalence, Mortality) among Pharmacologically Treated T2DM-patients in Hungary between 2001-2016

Dr. Peter Kempler, Professor, Department of Medicine, Semmelweis University, Hungary

16:20-16:45

Speech Opportunity Available
Abstract and Biography: Submit Here

16:45-17:10

Title: New Era in Management of Type 2 Diabetes

Dr. Mohsen Khalid, National Institute of Diabetes and Endocrinology, Egypt

   

Session 443: CMO/CRO and Outsourcing Services

Day 3: Afternoon, July. 16, 2021

Chair

Dr. Albin (Jim) Nelson, Senior Principal/Owner, Schwegman Lundberg Woessner P.A., USA

Time

 

13:30-13:35

Chair's Introduction

13:35-14:00

Title: Occupational Medicine and Addiction in Severe Apnea Syndrom Patients: How to Prevent the Vicious Circle?

Dr. Raphael Serreau, Professor, SMP PARADICT-O Orléans Métropole INSERM EA Psycomadd Paris Sud Saclay, France

14:00-14:25

Speech Opportunity Available
Abstract and Biography: Submit Here

14:25-14:50

Title: Top Ten Points for a Researcher to Win a Patent Grant or Why Do I Need a Patent Anyway?

Dr. Albin (Jim) Nelson, Senior Principal/Owner, Schwegman Lundberg Woessner P.A., USA

14:50-15:15

Speech Opportunity Available
Abstract and Biography: Submit Here

15:15-15:30

Coffee Break

15:30-15:55

Title: TBD

Dr. Abhay Deshpande, Director, Global Innovation & Strategy, JRF Global, India

15:55-16:20

Speech Opportunity Available
Abstract and Biography: Submit Here

16:20-16:45

Title: TBD

Ms. Marie Walsh, European Patent Attorney, Hanna Moore + Curley, Ireland

16:45-17:10

Speech Opportunity Available
Abstract and Biography: Submit Here

 

 



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