| BIT's 16th Annual Congress of International Drug Discovery Science and Technology-2018 | ||||
| Theme: Rethinking the Next Big Things in Pharma Innovations | ||||
| Time: August 16-19, 2018 Place: Boston Marriott Cambridge, USA |
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| Scientific Program | ||||
| Stream 1 | Stream 2 | Stream 3 | Stream 4 | Stream 5 |
| Stream 2: Drug Discovery X-Hubs -New Vision on Drug Discovery Science and Technology |
Substream 2-1: Dynamic Bio X-Hub |
| Substream 2-2: Enabled Technologies for Drug Discovery |
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Session 2201: Novel Analytical Technology for Drug Discovery Day 1: Afternoon, Thursday, August 16, 2018 Place: Enterprise Room, 3rd Floor 13:30-17:10 |
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| Chair: Dr. Kerstin Walke, Head of Pharmaceutical Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Germany | |||
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Co-Chair: Dr. Robert G. Lowery, President & CEO, BellBrook Labs, USA |
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| Time | FaceOn | Speeches and Speakers | |
| 13:30-13:35 | Chair's Introduction | ||
| 13:35-13:55 |  |
Title: World's First Fully (Hybrid) Integrated and Waferscale Manufacturable Photonic Interferometric Biosensor-array Chip-module with Unparalleled Sensitivity and Reproducibility, Applicable in Both Drug Screening/Optimization and Companion Diagnostics Dr. Henk Leeuwis, Senior Vice President, Strategy and Innovation, LioniX International BV, The Netherlands |
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| 13:55-14:15 |  |
Title: Formulation of NBE: The Polysorbat Discussion Current Overview Relates Issues Degradation Pathways and Potential Solutions Challenges in Analytics Dr. Kerstin Walke, Head of Pharmaceutical Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Germany |
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| 14:15-14:35 |  |
Title: Advances in Capillary Zone Electrophoresis for Charge Heterogeneity Testing of Monoclonal Antibodies Dr. Mark Lies, Senior Manager, CE & BioPharma, SCIEX, USA |
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| 14:35-14:55 |  |
Title: Advances in NGS Library Prep QC : Automated Pulsed-field Capillary Electrophoresis with Femtogram Level Detection Dr. Kit-Sum Wong, Director, Advanced Analytical Technologies Inc., USA |
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| 14:55-15:15 |  |
Title: Solutions for Automation of GMP Assays by Catalent Biologics Mr. Christopher Hepler, Group Leader, Biologics Analytical Services, Catalent Biologicss, USA |
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| 15:15-15:30 | Coffee Break | ||
| 15:30-15:50 |  |
Title: Appliction of Multiple Configurations of a Photonic Based Microscale Calorimeter in the Drug Discovery Process
Dr. Gregory Kowalski, Associate Professor, Department of Mechanical and Industrial Engineering, Northeastern University, USA |
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| 15:50-16:10 |  |
Title: Measuring Drug Residence Times in an HTS Format with the Transcreener® ADP2 Kinase Assay Dr. Robert G. Lowery, President & CEO, BellBrook Labs, USA |
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| 16:10-16:30 |  |
Title: Drugging the Undruggable: Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Inhibitor of Cadherin Homophilic Interaction Dr. Emilio Parisini, Group Leader, Istituto Italiano di Tecnologia, Italy |
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| 16:30-16:50 |  |
Title: Microfluidic Impedance Cytometry for Prediction of Patient Response to Targeted Cancer Therapy: A Data-driven Approach Dr. Mehdi Javanmard, Assistant Professor, Rutgers University, USA |
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| 16:50-17:10 |  |
Title: Following Fluorinated Drugs by Molecular Absorption Spectrometry – From Cancer Cells to Body Fluids Mr. Carlos Abad Andrade, Research Associate, Federal Institute for Materials Research and Testing -BAM, Germany |
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| 18:00-20:00 | Welcome Banquet & Art Performance | ||
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Session 2202: Other Enabled Technologies for Drug Discovery Day 2: Afternoon, Friday, August 17, 2018 Place: Discovery Room, 3rd Floor 13:30-17:10 |
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| Chair: Dr. Chengcang C. Wu, CEO & Founder, Intact Genomics, Inc., USA | |||
| Co-Chair: Mr. Lekhram Changoer, CTO/Director, AXIM Biotechnologies, USA/The Netherlands | |||
| Time | FaceOn | Speeches and Speakers | |
| 13:30-13:35 | Chair's Introduction | ||
| 13:35-13:55 |  |
Title: Chemical Biology Approach for Biologics Drug Discovery and the Identification of Antibody-drug Conjugate T-CE-040
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| 13:55-14:15 |  |
Title: Retrosynthetic Software for Practicing Chemists: Novel and Efficient in Silico Pathway Design Validated at the Bench Dr. Lindsey Hess Rickershauser, Technical Application Scientist, Cheminformatics Technologies, MilliporeSigma (a Business of Merck KGaA, Germany), USA |
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| 14:15-14:35 |  |
Title: Revive Large-scale Natural Product and Drug Discovery from Microbes and Soil Metagenomes Dr. Chengcang C. Wu, CEO & Founder, Intact Genomics, Inc., USA |
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| 14:35-14:55 |  |
Title: Novel Natural Product-based Macrocyclic Platform: MacroEvoLution Dr. Dietmar Wolf, Executive Vice President, AnalytiCon Discovery, LCC, Germany |
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| 14:55-15:15 |  |
Title: Metabolic Detection of Bruton’s Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells Dr. Seung-Cheol Lee, Research Assistant Professor,Department of Radiology, University of Pennsylvania, USA |
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| 15:15-15:30 | Coffee Break | ||
| 15:30-15:50 |  |
Title: Novel cGMP Technologies for Extraction, Purification and Conversion of Cannabinoids for the Pharmaceutical Industry Mr. Lekhram Changoer, CTO/Director, AXIM Biotechnologies, USA/The Netherlands
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| 15:50-16:10 |  |
Title: Heterogeneous Catalysis for Drug Synthesis Dr. Antonio Leyva-Perez, Distinguished Researcher, Universidad Politécnica de Valencia-Consejo Superior de Investigaciones Científicas, Spain |
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| 16:10-16:30 |  |
Title: Organolithium Chemistry Using Flow Microreactors Dr. Aiichiro Nagaki, Associate Professor, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Japan |
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| 16:30-16:50 |  |
Title: Hollow Fiber Model - in vivo Screening in Cancer Drug Discovery Dr. Bettina Stahnke, Business Development Manager, ProQinase GmbH, Germany |
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| 16:50-17:10 |  |
Title: Responsive Molecular Imaging Biosensors for Precise Therapeutic Solutions in Regenerative Medicine Dr. Ethel J. Ngen, Research Faculty, Johns Hopkins University School of Medicine, USA |
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