| Scientific Program | ||||
| Stream 1 | Stream 2 | Stream 3 | Stream 4 | Stream 5 |
| Stream 3: Breaking Preclinical and Clinical Research |
Stream 3-1: Novel Targets Discovery |
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Session 311: Cancer Drug Targets – Part I |
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Day 1: Afternoon, Thursday, July 25, 2019 Place: Room H, 1st Floor |
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Chair: Dr. Dennis Paul, Professor, LSU Health Sciences Center – New Orleans, USA |
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Co-Chair: Dr. Takuma Hayashi, Professor, National Hospital Organization Kyoto Medical Center, Japan |
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| Time | Speeches and Speakers |
| 13:30-13:35 |
Chair’s Introduction |
| 13:35-13:55 |
Title: Bioactivity of Nucleolin-targeting Aptamer AS1411 Hinges on the Function of mTOR Dr. Junsheng Lin, Professor, Huaqiao University, China |
| 13:55-14:15 |
Title: Alox5 Blockade Eradicates JAK2V617F-induced Polycythemia Vera in Mice |
| 14:15-14:35 |
Title: Interleukin-2 Receptor Expression α-chain (CD25) Expression in Acute Myeloid Leukemia Dr. Kazunori Nakase, Director, Cancer Center, Mie University Hospital, Japan |
| 14:35-14:55 |
Title: LMP2/1i as Tumor-suppressor Defines New Targets for Uterine Leiomyosarcoma Therapy |
| 14:55-15:15 | Title: Targeting ncRNAs for Cancer Therapy Dr. Yangchao Chen, Associate Professor, The Chinese University of Hong Kong, Hong Kong, China |
| 15:15-15:30 |
Coffee Break |
| 15:30-15:50 |
Title: Tropomyosin Drugs Synergise with Microtubule Drugs to Improve Their Anti-cancer Activity Dr. Peter Gunning, Professor, UNSW Sydney, Australia |
| 15:50-16:10 |
Title: Targeted Osmotic Lysis of Advanced-stage Carcinomas Using Pulsed Magnetic Fields and Pharmacological Blockade of Sodium Pumps Dr. Dennis Paul, Professor, LSU Health Sciences Center – New Orleans, USA |
| 16:10-16:30 |
Title: Long Noncoding RNA STXBP5 - AS1 Inhibits the Proliferation, Migration, and Invasion via Preventing the PI3K/AKT against STXBP5 Expression in Various Tumors Dr. Jie Yao, Attending Physician, Zhongnan Hospital of Wuhan University; General Manager, Wuhan Bojie Biomedical Science and Technology CO., LTD., China |
| 16:30-16:50 |
Title: Anti-E-selectin Aptamers (ESTA) Prevent Cancer Metastasis and Enhance the Effects of Anticancer Drugs Dr. Yoshihiro Morita, Clinical Fellow, Osaka University, Japan |
| 16:50-17:10 | Title: Griffipavixanthone Exhibits Potent Antitumor Activity against Ovarian Cancer in vitro and in vivo Dr. Xia Liu, Associate Professor, Key Laboratory of Longevity and Ageing-Related Disease of Chinese Ministry of Education, Centre for Translational Medicine and School of Preclinical Medicine, Guangxi Medical University, China |
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Session 312: Cancer Drug Targets – Part II |
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Day 2: Afternoon, Friday, July 26, 2019 Place: Room F, 1st Floor |
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Chair: Dr. Yong Zhu, Associate Professor, Yale University, USA |
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| Co-Chair: Dr. Haiching Ma, CSO, Reaction Biology Corporation, USA | |
| Time | Speeches and Speakers |
| 13:30-13:35 |
Chair’s Introduction |
| 13:35-13:55 |
Title: Differential Drug Effects on Differing Subsets of Cancer Stem Cells Present in Carcinoma Dr. Ian C. Mackenzie, Professor of Stem Cell Science, Blizard Institute, Queen Mary University of London, UK |
| 13:55-14:15 |
Title: Discovery Epigenetic Inhibitors for Epigenetic Modifiers Dr. Haiching Ma, CSO, Reaction Biology Corporation, USA |
| 14:15-14:35 |
Title: opnMe.com: The New Boehringer Ingelheim´s Open Innovation Portal to Foster Innovation Dr. Florian Montel, Head of opnMe.com and CNS Project Leader in Medicinal Chemistry, Boehringer Ingelheim, Germany |
| 14:35-14:55 |
Title: A Novel PiRNA-based Drug Candidate for Cancer Treatment Dr. Yong Zhu, Associate Professor, Yale University, USA |
| 14:55-15:15 |
Title: The NCOR2 Splice Variant as Genomic Biomarker for Breast Cancer Dr. Ui-Soon Khoo, Ada Chan Professor in Oncological Pathology, The University of Hong Kong, Hong Kong, China |
| 15:15-15:30 |
Coffee Break |
| 15:30-15:50 |
Keynote Speech Title: Individualized Approach to Predicting Sensitivity to Targeted Therapeutics in Recurrent Glioblastoma: Past, Present and Future Dr. Ella L. Kim, Director of the Translational and Experimental Neurooncology Lab, Johannes Gutenberg University Medical Centre, Germany |
| 15:50-16:10 |
Title: Dual Roles of SH3BGRL as Either a Tumor Suppressor or a Promoter in Breast Cancer Dr. Haihe Wang, Professor, Sun Yat-Sen University, China |
| 16:10-16:30 | Title: PD-L1 Expression in Human Breast Cancer by Immunohistochemistry
Dr. Lei Huo, Associate Professor, The University of Texas, USA |
| 16:30-16:50 | Title: Specific Target in Osteosarcoma: miR-375 and Its Sponge CircFAT1
Dr. Shuying Shen, Assistant Professor, Zhejiang University, China |
| 16:50-17:10 |
Title: TM4SF1 is a Novel Biomarker in Regulating the Malignancy and Gemcitabine Resistance for Bladder Cancer Dr. Rui Cao, Department of Urology, Beijing Friendship Hospital, Capital Medical University, China |
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